7VSB
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7VSC
| E. coli Ribonuclease HI in complex with one Mg2+ (1) | 分子名称: | MAGNESIUM ION, Ribonuclease HI, SULFATE ION | 著者 | Liao, Z, Oyama, T. | 登録日 | 2021-10-26 | 公開日 | 2022-03-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Pivotal role of a conserved histidine in Escherichia coli ribonuclease HI as proposed by X-ray crystallography. Acta Crystallogr D Struct Biol, 78, 2022
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4NW5
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5WZT
| Crystal structure of human secreted phospholipase A2 group IIE with Compound 14 | 分子名称: | 2-[1-[(3-bromophenyl)methyl]-2-methyl-3-oxamoyl-indol-4-yl]oxyethanoic acid, CALCIUM ION, DIMETHYL SULFOXIDE, ... | 著者 | Hou, S, Xu, J, Xu, T, Liu, J. | 登録日 | 2017-01-18 | 公開日 | 2018-01-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE Sci Rep, 7, 2017
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7VSD
| E. coli Ribonuclease HI in complex with one Mg2+ (2) | 分子名称: | MAGNESIUM ION, Ribonuclease HI, SULFATE ION | 著者 | Liao, Z, Oyama, T. | 登録日 | 2021-10-26 | 公開日 | 2022-03-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Pivotal role of a conserved histidine in Escherichia coli ribonuclease HI as proposed by X-ray crystallography. Acta Crystallogr D Struct Biol, 78, 2022
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5WNL
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6EMH
| Crystal structure of JNK3 in complex with a pyridinylimidazole inhibitor | 分子名称: | 1,2-ETHANEDIOL, 4-(4-methyl-1~{H}-imidazol-5-yl)-~{N}-(4-morpholin-4-ylphenyl)pyridin-2-amine, BETA-MERCAPTOETHANOL, ... | 著者 | Macedo, J.T, Stehle, T, Blaum, B.S. | 登録日 | 2017-10-02 | 公開日 | 2018-08-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structural Optimization of a Pyridinylimidazole Scaffold: Shifting the Selectivity from p38 alpha Mitogen-Activated Protein Kinase to c-Jun N-Terminal Kinase 3. ACS Omega, 3, 2018
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7VSE
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4NUQ
| Crystal structure of mouse N-cadherin EC1-2 W2F | 分子名称: | CALCIUM ION, Cadherin-2 | 著者 | Jin, X. | 登録日 | 2013-12-03 | 公開日 | 2014-09-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.116 Å) | 主引用文献 | Structural and energetic determinants of adhesive binding specificity in type I cadherins. Proc.Natl.Acad.Sci.USA, 111, 2014
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6EQM
| Crystal Structure of Human BACE-1 in Complex with CNP520 | 分子名称: | Beta-secretase 1, ~{N}-[6-[(3~{R},6~{R})-5-azanyl-3,6-dimethyl-6-(trifluoromethyl)-2~{H}-1,4-oxazin-3-yl]-5-fluoranyl-pyridin-2-yl]-3-chloranyl-5-(trifluoromethyl)pyridine-2-carboxamide | 著者 | Rondeau, J.-M, Wirth, E. | 登録日 | 2017-10-13 | 公開日 | 2018-09-19 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease. EMBO Mol Med, 10, 2018
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6JKM
| Crystal structure of BubR1 kinase domain | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. | 登録日 | 2019-03-01 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
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7E6Q
| Crystal structure of influenza A virus neuraminidase N5 complexed with 4'-phenyl-1,2,3-triazolylated oseltamivir carboxylate | 分子名称: | (3R,4R,5S)-4-acetamido-3-pentan-3-yloxy-5-(4-phenyl-1,2,3-triazol-1-yl)cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Wang, P.F, Babayemi, O.O, Li, C.N, Fu, L.F, Zhang, S.S, Qi, J.X, Lv, X, Li, X.B. | 登録日 | 2021-02-23 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-based design of 5'-substituted 1,2,3-triazolylated oseltamivir derivatives as potent influenza neuraminidase inhibitors. Rsc Adv, 11, 2021
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7MP8
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7MP9
| Crystal structure of the cytosolic domain of Tribolium castaneum PINK1 phosphorylated at Ser205 in complex with ADP analog | 分子名称: | AMP PHOSPHORAMIDATE, MAGNESIUM ION, SULFATE ION, ... | 著者 | Rasool, S, Veyron, S, Trempe, J.F. | 登録日 | 2021-05-04 | 公開日 | 2021-12-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex. Mol.Cell, 82, 2022
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7MNH
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6JLB
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7MX3
| Crystal structure of human RIPK3 complexed with GSK'843 | 分子名称: | 1,2-ETHANEDIOL, 3-(1,3-benzothiazol-5-yl)-7-(1,3-dimethyl-1H-pyrazol-5-yl)thieno[3,2-c]pyridin-4-amine, Receptor-interacting serine/threonine-protein kinase 3 | 著者 | Davies, K.A, Czabotar, P.E. | 登録日 | 2021-05-18 | 公開日 | 2021-11-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | 主引用文献 | Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis. Nat Commun, 12, 2021
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5Y1I
| The crystal structure of GfsF | 分子名称: | Cytochrome P450, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Miyanaga, A, Kudo, F, Eguchi, T. | 登録日 | 2017-07-20 | 公開日 | 2017-09-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Substrate Recognition by a Dual-Function P450 Monooxygenase GfsF Involved in FD-891 Biosynthesis Chembiochem, 18, 2017
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6J87
| Crystal structure of HinD with NMFT and NO | 分子名称: | N-[(2S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl]-Nalpha-methyl-L-phenylalaninamide, NITRIC OXIDE, Nocardicin N-oxygenase, ... | 著者 | Fei, H, Mori, T, Abe, I. | 登録日 | 2019-01-18 | 公開日 | 2019-08-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis for the P450-catalyzed C-N bond formation in indolactam biosynthesis. Nat.Chem.Biol., 15, 2019
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5WRA
| Crystal structure of hen egg-white lysozyme | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Sugahara, M, Suzuki, M, Masuda, T, Inoue, S, Nango, E. | 登録日 | 2016-12-01 | 公開日 | 2017-12-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Hydroxyethyl cellulose matrix applied to serial crystallography Sci Rep, 7, 2017
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6EBB
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5Y5F
| Structure of cytochrome P450nor in NO-bound state: damaged by low-dose (0.72 MGy) X-ray | 分子名称: | GLYCEROL, NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, ... | 著者 | Tosha, T, Nomura, T, Nishida, T, Ueno, G, Murakami, H, Yamashita, K, Hirata, K, Yamamoto, M, Ago, H, Sugimoto, H, Shiro, Y, Kubo, M. | 登録日 | 2017-08-09 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate. Nat Commun, 8, 2017
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4Q7Y
| Neutrophil serine protease 4 (PRSS57) apo form 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Serine protease 57, ... | 著者 | Eigenbrot, C, Lin, S.J, Dong, K.C. | 登録日 | 2014-04-25 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structures of neutrophil serine protease 4 reveal an unusual mechanism of substrate recognition by a trypsin-fold protease. Structure, 22, 2014
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5Y4D
| Crystal Structure of AnkB Ankyrin Repeats in Complex with AnkR/AnkB Chimeric Autoinhibition Segment | 分子名称: | Ankyrin-1,Ankyrin-2,Ankyrin-2, SULFATE ION | 著者 | Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M. | 登録日 | 2017-08-03 | 公開日 | 2017-09-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions. Elife, 6, 2017
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7DGN
| The Co-bound dimeric structure of K79H/G80A/H81A myoglobin | 分子名称: | COBALT (II) ION, Myoglobin, OXYGEN ATOM, ... | 著者 | Nagao, S, Idomoto, A, Shibata, N, Higuchi, Y, Hirota, S. | 登録日 | 2020-11-12 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Rational design of metal-binding sites in domain-swapped myoglobin dimers. J.Inorg.Biochem., 217, 2021
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