PDB: 694 件ウェブページステータス検索Chemie searchBIRD

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8F0O	cryo-EM structure of homomeric kainate receptor GluK2 in resting (apo) state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... 著者 Bogdanovic, N, Tajima, N. 登録日 2022-11-03 公開日 2023-11-08 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (2.99 Å) 主引用文献 Partial agonism in kainate receptors To Be Published
8FPC	Conformation 1 of the ligand binding domain (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-04 公開日 2024-02-28 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (2.78 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FP4	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610) 分子名称: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit 著者 Nakagawa, T. 登録日 2023-01-04 公開日 2024-02-28 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPH	Conformation 2 of the ligand binding domain (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-04 公開日 2024-02-28 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FP9	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg) 分子名称: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ... 著者 Nakagawa, T. 登録日 2023-01-04 公開日 2024-02-28 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (2.44 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPS	GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K) 分子名称: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-02-28 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.38 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPL	LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg) 分子名称: 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione, CYCLOTHIAZIDE, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-04 公開日 2024-02-28 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.81 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQF	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260) 分子名称: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit 著者 Nakagawa, T. 登録日 2023-01-06 公開日 2024-02-28 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.29 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPK	LBD conformation 1 of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg) 分子名称: 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione, CYCLOTHIAZIDE, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-04 公開日 2024-02-28 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ6	LBD of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-02-28 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FR0	LBD conformation 3 (LBDconf3) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-06 公開日 2024-02-28 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ3	LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-02-28 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.17 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQG	LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-06 公開日 2024-02-28 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPG	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg) 分子名称: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit 著者 Nakagawa, T. 登録日 2023-01-04 公開日 2024-02-28 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (2.32 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ2	LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-02-28 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ1	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150) 分子名称: CALCIUM ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-02-28 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (5.59 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ5	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110) 分子名称: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-02-28 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (2.34 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQD	LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-06 公開日 2024-02-28 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQB	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10) 分子名称: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ... 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-02-28 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.36 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQH	LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 150mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na260) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-06 公開日 2024-02-28 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ8	LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-02-28 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.11 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQE	LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-06 公開日 2024-02-28 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPV	LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-03-06 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPY	LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-03-06 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPZ	LBD conformation 3 (LBDconf3) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610) 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 著者 Nakagawa, T. 登録日 2023-01-05 公開日 2024-03-06 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024

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