8BJH
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![BU of 8bjh by Molmil](/molmil-images/mine/8bjh) | chimera of the inactive ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, with the double mutation K3528M and K3535I, fused to a proline-Rich-Domain (PRD) and profilin, bound to Latrunculin B-ADP-Mg-actin | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | 著者 | Teixeira-Nunes, M, Renault, L, Retailleau, P. | 登録日 | 2022-11-04 | 公開日 | 2023-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19, 2023
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8BJI
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![BU of 8bji by Molmil](/molmil-images/mine/8bji) | chimera of ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo fused to a proline-Rich-Domain (PRD) and profilin, bound to ADP-Mg-actin and a sulfate ion | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | 著者 | Teixeira-Nunes, M, Renault, L, Retailleau, P. | 登録日 | 2022-11-04 | 公開日 | 2023-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19, 2023
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3UIO
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![BU of 3uio by Molmil](/molmil-images/mine/3uio) | Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II | 分子名称: | E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... | 著者 | Gareau, J.R, Reverter, D, Lima, C.D. | 登録日 | 2011-11-05 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
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8BJJ
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![BU of 8bjj by Molmil](/molmil-images/mine/8bjj) | ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to ATP-Mg-actin, human profilin 1 and a sulfate ion | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | 著者 | Teixeira-Nunes, M, Renault, L, Retailleau, P. | 登録日 | 2022-11-04 | 公開日 | 2023-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | 主引用文献 | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19, 2023
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8BR0
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![BU of 8br0 by Molmil](/molmil-images/mine/8br0) | ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin (residue Q3455 to L3863) in complex with 3'deoxyCTP and two manganese cations bound to Latrunculin-B-ADP-Mn-actin | 分子名称: | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | 著者 | Texeira-Nuns, M, Retailleau, P, Renault, L. | 登録日 | 2022-11-22 | 公開日 | 2023-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.218 Å) | 主引用文献 | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19, 2023
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8BI7
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![BU of 8bi7 by Molmil](/molmil-images/mine/8bi7) | Binary structure of 14-3-3s and PKR phosphopeptide | 分子名称: | 14-3-3 protein sigma, MAGNESIUM ION, PKR phosphopeptide | 著者 | Somsen, B.A, Ottmann, C. | 登録日 | 2022-11-01 | 公開日 | 2023-03-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERR gamma Protein-Protein Interaction as a Molecular Glue Drug Discovery Approach. J.Am.Chem.Soc., 145, 2023
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6SKL
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![BU of 6skl by Molmil](/molmil-images/mine/6skl) | Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1 | 分子名称: | Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA fork, ... | 著者 | Yeeles, J, Baretic, D, Jenkyn-Bedford, M. | 登録日 | 2019-08-16 | 公開日 | 2020-05-06 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork. Mol.Cell, 78, 2020
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1FPN
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![BU of 1fpn by Molmil](/molmil-images/mine/1fpn) | HUMAN RHINOVIRUS SEROTYPE 2 (HRV2) | 分子名称: | COAT PROTEIN VP1, COAT PROTEIN VP2, COAT PROTEIN VP3, ... | 著者 | Verdaguer, N, Blaas, D, Fita, I. | 登録日 | 2000-08-31 | 公開日 | 2000-09-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of human rhinovirus serotype 2 (HRV2). J.Mol.Biol., 300, 2000
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5VP8
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![BU of 5vp8 by Molmil](/molmil-images/mine/5vp8) | I38T mutant of 2009 H1N1 PA Endonuclease | 分子名称: | 1-[(3R,5S,7R)-1,5,7,9-tetrakis(2-oxopyrrolidin-1-yl)nonan-3-yl]-1,3-dihydro-2H-pyrrol-2-one, MANGANESE (II) ION, Polymerase acidic protein, ... | 著者 | Kumar, G, White, S.W. | 登録日 | 2017-05-04 | 公開日 | 2018-04-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors. MBio, 9, 2018
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6R1T
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![BU of 6r1t by Molmil](/molmil-images/mine/6r1t) | Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 1, free nuclesome | 分子名称: | DNA (147-MER), HISTONE H2A, Histone H2A, ... | 著者 | Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. | 登録日 | 2019-03-15 | 公開日 | 2019-04-24 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | 主引用文献 | A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
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6BCA
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![BU of 6bca by Molmil](/molmil-images/mine/6bca) | |
4KN6
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![BU of 4kn6 by Molmil](/molmil-images/mine/4kn6) | Crystal structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with 6-fluoro-3-hydroxy-2-pyrazinecarboxamide (T-705) ribose-5'-monophosphate | 分子名称: | 6-fluoro-3-oxo-4-(5-O-phosphono-beta-D-ribofuranosyl)-3,4-dihydropyrazine-2-carboxamide, Hypoxanthine-guanine phosphoribosyltransferase | 著者 | Naesens, L, Guddat, L, Keough, D, van Kuilenburg, A.B.P, Meijer, J, Vande Voorde, J, Balzarini, J. | 登録日 | 2013-05-08 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.728 Å) | 主引用文献 | Role of human hypoxanthine Guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir). Mol.Pharmacol., 84, 2013
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4MDE
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![BU of 4mde by Molmil](/molmil-images/mine/4mde) | Structure of bacterial polynucleotide kinase product complex bound to GDP and DNA | 分子名称: | DNA (5'-D(P*CP*CP*TP*GP*T)-3'), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Shuman, S, Das, U, Wang, L.K, Smith, P, Jacewicz, A. | 登録日 | 2013-08-22 | 公開日 | 2013-11-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP*Mg2+ and 5'-OH oligonucleotide and a product complex with GDP*Mg2+ and 5'-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition. Nucleic Acids Res., 42, 2014
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5QS6
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![BU of 5qs6 by Molmil](/molmil-images/mine/5qs6) | PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z44592329 | 分子名称: | N-phenyl-N'-pyridin-3-ylurea, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A.E, Sherestha, L, Fernandez-Cid, A, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-06-19 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | PanDDA analysis group deposition To Be Published
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4MDF
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![BU of 4mdf by Molmil](/molmil-images/mine/4mdf) | Structure of bacterial polynucleotide kinase Michaelis complex bound to GTP and DNA | 分子名称: | CITRIC ACID, DNA (5'-D(*CP*CP*TP*GP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Shuman, S, Das, U, Wang, L.K, Smith, P, Jacewicz, A. | 登録日 | 2013-08-22 | 公開日 | 2013-11-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.727 Å) | 主引用文献 | Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP*Mg2+ and 5'-OH oligonucleotide and a product complex with GDP*Mg2+ and 5'-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition. Nucleic Acids Res., 42, 2014
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3UIN
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![BU of 3uin by Molmil](/molmil-images/mine/3uin) | Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2 | 分子名称: | E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... | 著者 | Gareau, J.R, Reverter, D, Lima, C.D. | 登録日 | 2011-11-05 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.597 Å) | 主引用文献 | Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
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3WRY
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![BU of 3wry by Molmil](/molmil-images/mine/3wry) | Crystal structure of helicase complex 2 | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Matsumura, H, Katoh, E. | 登録日 | 2014-02-27 | 公開日 | 2014-08-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for the recognition-evasion arms race between Tomato mosaic virus and the resistance gene Tm-1 Proc.Natl.Acad.Sci.USA, 111, 2014
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3WRX
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![BU of 3wrx by Molmil](/molmil-images/mine/3wrx) | Crystal structure of helicase complex 1 | 分子名称: | CESIUM ION, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Matsumura, H, Katoh, E. | 登録日 | 2014-02-27 | 公開日 | 2014-08-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the recognition-evasion arms race between Tomato mosaic virus and the resistance gene Tm-1 Proc.Natl.Acad.Sci.USA, 111, 2014
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7P0M
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![BU of 7p0m by Molmil](/molmil-images/mine/7p0m) | |
7P09
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![BU of 7p09 by Molmil](/molmil-images/mine/7p09) | |
7P0B
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![BU of 7p0b by Molmil](/molmil-images/mine/7p0b) | |
8T2T
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![BU of 8t2t by Molmil](/molmil-images/mine/8t2t) | Structure of a group II intron ribonucleoprotein in the post-ligation (post-2F) state | 分子名称: | AMMONIUM ION, Group II intron reverse transcriptase/maturase, MAGNESIUM ION, ... | 著者 | Xu, L, Liu, T, Chung, K, Pyle, A.M. | 登録日 | 2023-06-06 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into intron catalysis and dynamics during splicing. Nature, 624, 2023
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8OTZ
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![BU of 8otz by Molmil](/molmil-images/mine/8otz) | 48-nm repeat of the native axonemal doublet microtubule from bovine sperm | 分子名称: | ATP6V1F neighbor, CFAP97 domain containing 1, Chromosome 13 C20orf85 homolog, ... | 著者 | Leung, M.R, Zeng, J, Zhang, R, Zeev-Ben-Mordehai, T. | 登録日 | 2023-04-21 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural specializations of the sperm tail. Cell, 186, 2023
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7K3J
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![BU of 7k3j by Molmil](/molmil-images/mine/7k3j) | |
7K3K
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![BU of 7k3k by Molmil](/molmil-images/mine/7k3k) | |