Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1

This is a large structure.

Summary for 6SKL

EMDB information10227
DescriptorDNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ... (19 entities in total)
Functional Keywordsprotein-dna complex, replisome, aaa+ helicase, cmg, gins, fork dna, mcm, fork protection complex, cip-box, replication
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Total number of polymer chains18
Total molecular weight1326612.85
Yeeles, J.,Baretic, D.,Jenkyn-Bedford, M. (deposition date: 2019-08-16, release date: 2020-05-06, Last modification date: 2020-05-20)
Primary citation
Baretic, D.,Jenkyn-Bedford, M.,Aria, V.,Cannone, G.,Skehel, M.,Yeeles, J.T.P.
Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork.
Mol.Cell, 2020
PubMed: 32369734 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2020.04.012
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers00 0.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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