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2AAO
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Regulatory apparatus of Calcium Dependent protein kinase from Arabidopsis thaliana
分子名称: CALCIUM ION, Calcium-dependent protein kinase, isoform AK1
著者Chandran, V, Stollar, E.J, Lindorff-Larsen, K, Harper, J.F, Chazin, W.J, Dobson, C.M, Luisi, B.F, Christodoulou, J.
登録日2005-07-13
公開日2005-12-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition.
J.Mol.Biol., 357, 2006
5J4C
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BU of 5j4c by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (soaked) and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S.
登録日2016-03-31
公開日2016-04-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome.
Nucleic Acids Res., 44, 2016
5WI0
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BU of 5wi0 by Molmil
Crystal structure of human NAMPT with fragment 2: 2-[(2-fluorophenyl)amino]-6-propylpyrimidin-4(3H)-one
分子名称: 2-[(2-fluorophenyl)amino]-6-propylpyrimidin-4(3H)-one, Nicotinamide phosphoribosyltransferase
著者Longenecker, K.L, Raich, D, Korepanova, A.V.
登録日2017-07-18
公開日2018-01-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Fragment-based discovery of a potent NAMPT inhibitor.
Bioorg. Med. Chem. Lett., 28, 2018
5IYB
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BU of 5iyb by Molmil
Human core-PIC in the open state
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ...
著者He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E.
登録日2016-03-24
公開日2016-05-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
5WKT
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BU of 5wkt by Molmil
3.2-Angstrom In situ Mylar structure of bovine opsin at 100 K
分子名称: Rhodopsin, SULFATE ION, Transducin Galpha peptide, ...
著者Broecker, J, Morizumi, T, Ou, W.-L, Ernst, O.P.
登録日2017-07-25
公開日2017-12-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions.
Nat Protoc, 13, 2018
5IYD
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BU of 5iyd by Molmil
Human core-PIC in the initial transcribing state (no IIS)
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ...
著者He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E.
登録日2016-03-24
公開日2016-05-18
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
298D
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BU of 298d by Molmil
TARGETING THE MINOR GROOVE OF DNA: CRYSTAL STRUCTURES OF TWO COMPLEXES BETWEEN FURAN DERIVATIVES OF BERENIL AND THE DNA DODECAMER D(CGCGAATTCGCG)2
分子名称: 2,5-BIS{[4-(N-ISOPROPYL)DIAMINOMETHYL]PHENYL}FURAN, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
著者Trent, J.O, Clark, G.R, Kumar, A, Wilson, W.D, Boykin, D.W, Hall, J.E, Tidwell, R.R, Blagburn, B.L, Neidle, S.
登録日1996-10-10
公開日1996-12-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Targeting the minor groove of DNA: crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2.
J.Med.Chem., 39, 1996
2HA4
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BU of 2ha4 by Molmil
Crystal structure of mutant S203A of mouse acetylcholinesterase complexed with acetylcholine
分子名称: ACETATE ION, ACETYLCHOLINE, Acetylcholinesterase, ...
著者Bourne, Y, Radic, Z, Sulzenbacher, G, Kim, E, Taylor, P, Marchot, P.
登録日2006-06-12
公開日2006-07-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding
J.Biol.Chem., 281, 2006
5X15
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BU of 5x15 by Molmil
Crystal structure of Streptomyces coelicolor RraAS2, an unusual member of the RNase ES inhibitor RraA protein family
分子名称: Putative transferase
著者Park, N, Jo, I, Ha, N.-C.
登録日2017-01-24
公開日2017-05-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.094 Å)
主引用文献Crystal structure of Streptomyces coelicolor RraAS2, an unusual member of the RNase E inhibitor RraA protein family
J. Microbiol., 55, 2017
2AEH
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BU of 2aeh by Molmil
Focal adhesion kinase 1
分子名称: Focal adhesion kinase 1
著者Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J.
登録日2005-07-22
公開日2005-10-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
2A1I
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BU of 2a1i by Molmil
Crystal Structure of the Central Domain of Human ERCC1
分子名称: DNA excision repair protein ERCC-1, MERCURY (II) ION
著者Tsodikov, O.V, Enzlin, J.H, Scharer, O.D, Ellenberger, T.
登録日2005-06-20
公開日2005-08-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2GJY
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BU of 2gjy by Molmil
NMR Solution Structure of Tensin1 PTB Domain
分子名称: Tensin
著者Leone, M, Pellecchia, M.
登録日2006-03-31
公開日2007-04-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The PTB domain of tensin: NMR solution structure and phosphoinositides binding studies.
Biopolymers, 89, 2007
5WE6
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BU of 5we6 by Molmil
70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Frank, J.
登録日2017-07-07
公開日2018-04-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
2ADA
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BU of 2ada by Molmil
ATOMIC STRUCTURE OF ADENOSINE DEAMINASE COMPLEXED WITH A TRANSITION-STATE ANALOG: UNDERSTANDING CATALYSIS AND IMMUNODEFICIENCY MUTATIONS
分子名称: 6-HYDROXY-7,8-DIHYDRO PURINE NUCLEOSIDE, ADENOSINE DEAMINASE, ZINC ION
著者Wilson, D.K, Quiocho, F.A.
登録日1994-12-02
公開日1995-03-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations.
Science, 252, 1991
5WI1
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BU of 5wi1 by Molmil
Crystal structure of human NAMPT with fragment 5: (3E)-3-[(phenylamino)methylidene]oxan-2-one
分子名称: (3E)-3-[(phenylamino)methylidene]oxan-2-one, Nicotinamide phosphoribosyltransferase, SULFATE ION
著者Longenecker, K.L, Raich, D, Korepanova, A.V.
登録日2017-07-18
公開日2018-01-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Fragment-based discovery of a potent NAMPT inhibitor.
Bioorg. Med. Chem. Lett., 28, 2018
2AJB
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BU of 2ajb by Molmil
Porcine dipeptidyl peptidase IV (CD26) in complex with the tripeptide tert-butyl-Gly-L-Pro-L-Ile (tBu-GPI)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-methyl-L-valyl-L-prolyl-L-isoleucine, ...
著者Engel, M, Hoffmann, T, Manhart, S, Heiser, U, Chambre, S, Huber, R, Demuth, H.U, Bode, W.
登録日2005-08-01
公開日2006-02-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV.
J.Mol.Biol., 355, 2006
5W8S
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BU of 5w8s by Molmil
Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations
分子名称: LITHIUM ION, Lipid-A-disaccharide synthase, SODIUM ION
著者Bohl, T.E, Aihara, H, Shi, K, Lee, J.K.
登録日2017-06-22
公開日2018-01-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of lipid A disaccharide synthase LpxB from Escherichia coli.
Nat Commun, 9, 2018
5WDT
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BU of 5wdt by Molmil
70S ribosome-EF-Tu H84A complex with GppNHp
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Brown, Z, Frank, J.
登録日2017-07-06
公開日2018-04-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WE4
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BU of 5we4 by Molmil
70S ribosome-EF-Tu wt complex with GppNHp
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Brown, Z, Frank, J.
登録日2017-07-07
公開日2018-04-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
7MFR
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BU of 7mfr by Molmil
Crystal Structure of a Fab fragment bound to peptide GGM
分子名称: Antibody fragment - Heavy Chain of fab, Antibody fragment - Light Chain of fab, GLY-GLY-MET, ...
著者Sudhamsu, J.
登録日2021-04-10
公開日2021-06-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.848 Å)
主引用文献Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W.
Nat Commun, 12, 2021
2HA7
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BU of 2ha7 by Molmil
Crystal structure of mutant S203A of mouse acetylcholinesterase complexed with butyrylthiocholine
分子名称: 2-(BUTYRYLSULFANYL)-N,N,N-TRIMETHYLETHANAMINIUM, 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, Acetylcholinesterase, ...
著者Bourne, Y, Radic, Z, Sulzenbacher, G, Kim, E, Taylor, P, Marchot, P.
登録日2006-06-12
公開日2006-07-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding
J.Biol.Chem., 281, 2006
5WST
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BU of 5wst by Molmil
Crystal structure of Myo7a SAH
分子名称: Unconventional myosin-VIIa
著者Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M.
登録日2016-12-08
公開日2017-06-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension
Structure, 25, 2017
7MTB
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BU of 7mtb by Molmil
Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6
分子名称: Fab6 heavy chain, Fab6 light chain, RETINAL, ...
著者Chen, Q, Chen, C.-L, Tesmer, J.J.G.
登録日2021-05-13
公開日2021-07-07
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
7MT8
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Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin
分子名称: RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ...
著者Chen, Q, Chen, C.-L, Tesmer, J.J.G.
登録日2021-05-13
公開日2021-07-07
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
7MIY
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Human N-type voltage-gated calcium channel Cav2.2 at 3.1 Angstrom resolution
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N, Gao, S, Yao, X.
登録日2021-04-18
公開日2021-07-07
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of human Ca v 2.2 channel blocked by the painkiller ziconotide.
Nature, 596, 2021

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