2ADA
ATOMIC STRUCTURE OF ADENOSINE DEAMINASE COMPLEXED WITH A TRANSITION-STATE ANALOG: UNDERSTANDING CATALYSIS AND IMMUNODEFICIENCY MUTATIONS
Replaces: 1ADASummary for 2ADA
Entry DOI | 10.2210/pdb2ada/pdb |
Descriptor | ADENOSINE DEAMINASE, ZINC ION, 6-HYDROXY-7,8-DIHYDRO PURINE NUCLEOSIDE, ... (4 entities in total) |
Functional Keywords | hydrolase, amino, zinc cofactor, beta/alpha barrel, transition-state inhibitor |
Biological source | Mus musculus (house mouse) |
Cellular location | Cell membrane; Peripheral membrane protein; Extracellular side (By similarity): P03958 |
Total number of polymer chains | 1 |
Total formula weight | 40381.24 |
Authors | Wilson, D.K.,Quiocho, F.A. (deposition date: 1994-12-02, release date: 1995-03-31, Last modification date: 2024-02-14) |
Primary citation | Wilson, D.K.,Rudolph, F.B.,Quiocho, F.A. Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations. Science, 252:1278-1284, 1991 Cited by PubMed: 1925539PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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