7MTB

Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6

Summary for 7MTB

• Entry DOI: 10.2210/pdb7mtb/pdb
• EMDB information: 23980
• Descriptor: Rhodopsin kinase GRK1, Fab6 heavy chain, Fab6 light chain, ... (6 entities in total)
• Functional Keywords: gpcr, signal desensitization, kinase, membrane protein, membrane protein-immune system complex, membrane, signaling protein-immune system complex, signaling protein/immune system
• Biological source: Bos taurus (Bovine); More
• Total number of polymer chains: 4
• Total formula weight: 149847.16

Authors

Chen, Q.,Chen, C.-L.,Tesmer, J.J.G. (deposition date: 2021-05-13, release date: 2021-07-07, Last modification date: 2021-08-25)

• Primary citation: Chen, Q.,Plasencia, M.,Li, Z.,Mukherjee, S.,Patra, D.,Chen, C.L.,Klose, T.,Yao, X.Q.,Kossiakoff, A.A.,Chang, L.,Andrews, P.C.,Tesmer, J.J.G.; Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.; Nature, 595:600-605, 2021; PubMed: 34262173; DOI: 10.1038/s41586-021-03721-x

Experimental method

ELECTRON MICROSCOPY (4 Å)