7MTB
Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | Rhodopsin kinase GRK1 | polymer | 543 | 61542.0 | 1 | UniProt (P28327) Pfam (PF00615) Pfam (PF00069) | Bos taurus (Bovine) | RK,G protein-coupled receptor kinase 1 |
| 2 | B (H) | Fab6 heavy chain | polymer | 234 | 25170.9 | 1 | Homo sapiens | ||
| 3 | C (L) | Fab6 light chain | polymer | 216 | 23509.0 | 1 | Homo sapiens | ||
| 4 | D (R) | Rhodopsin | polymer | 348 | 39031.5 | 1 | UniProt (P02699) Pfam (PF10413) Pfam (PF00001) | Bos taurus (Bovine) | |
| 5 | E (G) | SANGIVAMYCIN | non-polymer | 309.3 | 1 | Chemie (SGV) PubChem (16760643) PubChem (5153) PubChem (14978) PubChem (44330426) PubChem (57685061) PubChem (46875748) PubChem (70829033) PubChem (3007220) PubChem (89687375) PubChem (92209899) PubChem (92209900) PubChem (92209901) PubChem (6712998) PubChem (101037982) PubChem (10403057) PubChem (10448038) PubChem (142650208) PubChem (162968206) | |||
| 6 | F (R) | RETINAL | non-polymer | 284.4 | 1 | Chemie (RET) PubChem (1070) PubChem (23254473) PubChem (177675058) PubChem (638015) PubChem (87082476) PubChem (87110449) PubChem (87110609) PubChem (88398773) PubChem (88407543) PubChem (5280490) PubChem (5353924) PubChem (5381765) PubChem (6436079) PubChem (6436082) PubChem (11426127) PubChem (12227253) PubChem (12227254) PubChem (12227256) PubChem (12227257) PubChem (12227258) PubChem (12227259) PubChem (12227269) PubChem (12227270) PubChem (12227271) PubChem (134688327) PubChem (140510408) PubChem (145826762) PubChem (169423542) PubChem (172878320) |
Sequence modifications
G: 1 - 535 (UniProt: P28327)
| PDB | External Database | Details |
|---|---|---|
| Glu 5 | Ser 5 | engineered mutation |
| Glu 488 | Ser 488 | engineered mutation |
| Glu 489 | Thr 489 | engineered mutation |
| Val 536 | - | expression tag |
| Asp 537 | - | expression tag |
| His 538 | - | expression tag |
| His 539 | - | expression tag |
| His 540 | - | expression tag |
| His 541 | - | expression tag |
| His 542 | - | expression tag |
| His 543 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 149253.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 593.7 | |
| All* | Total formula weight | 149847.2 |
