7MTB
Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | Rhodopsin kinase GRK1 | polymer | 543 | 61542.0 | 1 | UniProt (P28327) Pfam (PF00615) Pfam (PF00069) | Bos taurus (Bovine) | RK,G protein-coupled receptor kinase 1 |
| 2 | B (H) | Fab6 heavy chain | polymer | 234 | 25170.9 | 1 | Homo sapiens | ||
| 3 | C (L) | Fab6 light chain | polymer | 216 | 23509.0 | 1 | Homo sapiens | ||
| 4 | D (R) | Rhodopsin | polymer | 348 | 39031.5 | 1 | UniProt (P02699) Pfam (PF10413) Pfam (PF00001) | Bos taurus (Bovine) | |
| 5 | E (G) | SANGIVAMYCIN | non-polymer | 309.3 | 1 | Chemie (SGV) | |||
| 6 | F (R) | RETINAL | non-polymer | 284.4 | 1 | Chemie (RET) |
Sequence modifications
G: 1 - 535 (UniProt: P28327)
| PDB | External Database | Details |
|---|---|---|
| Glu 5 | Ser 5 | engineered mutation |
| Glu 488 | Ser 488 | engineered mutation |
| Glu 489 | Thr 489 | engineered mutation |
| Val 536 | - | expression tag |
| Asp 537 | - | expression tag |
| His 538 | - | expression tag |
| His 539 | - | expression tag |
| His 540 | - | expression tag |
| His 541 | - | expression tag |
| His 542 | - | expression tag |
| His 543 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 149253.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 593.7 | |
| All* | Total formula weight | 149847.2 |
