Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations

Summary for 5W8S

Related5W8X 5W8N
DescriptorLipid-A-disaccharide synthase, SODIUM ION, LITHIUM ION, ... (4 entities in total)
Functional Keywordsglycosyltransferase b, rossmann-like, c-terminal swap, dimer, lipid a disaccharide synthase, raetz pathway, lipid a synthesis pathway, lipiopolysaccharide synthesis, transferase
Biological sourceEscherichia coli BL21(DE3)
Total number of polymer chains1
Total molecular weight42334.8
Bohl, T.E.,Aihara, H.,Shi, K.,Lee, J.K. (deposition date: 2017-06-22, release date: 2018-01-31, Last modification date: 2020-01-01)
Primary citation
Bohl, T.E.,Shi, K.,Lee, J.K.,Aihara, H.
Crystal structure of lipid A disaccharide synthase LpxB from Escherichia coli.
Nat Commun, 9:377-377, 2018
PubMed: 29371662 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-017-02712-9
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22410.3%0.7%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-08-05