5W8S
Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lipid-A-disaccharide synthase | polymer | 382 | 42281.9 | 1 | UniProt (A0A140NAT1) Pfam (PF02684) UniProt (by SIFTS) (P10441) | Escherichia coli BL21(DE3) | |
| 2 | B, C (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 3 | D (A) | LITHIUM ION | non-polymer | 6.9 | 1 | Chemie (LI) | |||
| 4 | E (A) | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A: 1 - 382 (UniProt: A0A140NAT1)
| PDB | External Database | Details |
|---|---|---|
| Ser 66 | Val 66 | engineered mutation |
| Ser 68 | Val 68 | engineered mutation |
| Ser 69 | Leu 69 | engineered mutation |
| Ser 72 | Leu 72 | engineered mutation |
| Ser 75 | Leu 75 | engineered mutation |
| Ser 76 | Leu 76 | engineered mutation |
| Ser 207 | Met 207 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42281.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 52.9 | |
| All* | Total formula weight | 42334.8 |
