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2X6U
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Crystal structure of human TBX5 in the DNA-free form
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, MAGNESIUM ION, T-BOX TRANSCRIPTION FACTOR TBX5
著者Stirnimann, C.U, Mueller, C.W.
登録日2010-02-22
公開日2010-04-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form.
J.Mol.Biol., 400, 2010
1O4X
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TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
分子名称: 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', Transcription factor SOX-2, ...
著者Clore, G.M, Williams, D.C.
登録日2003-07-17
公開日2004-01-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
J.Biol.Chem., 279, 2004
1K6O
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Crystal Structure of a Ternary SAP-1/SRF/c-fos SRE DNA Complex
分子名称: 5'-D(*CP*AP*CP*AP*GP*GP*AP*TP*GP*TP*CP*CP*AP*TP*AP*TP*TP*AP*GP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*CP*TP*AP*AP*TP*AP*TP*GP*GP*AP*CP*AP*TP*CP*CP*TP*GP*TP*G)-3', ETS-domain protein ELK-4, ...
著者Mo, Y, Ho, W, Johnston, K, Marmorstein, R.
登録日2001-10-16
公開日2002-01-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex.
J.Mol.Biol., 314, 2001
6PKZ
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Structure of human DNA polymerase beta N279A complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Koag, M.C, Lee, S.
登録日2019-06-30
公開日2020-07-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Structure of human DNA polymerase beta N279A complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP
To Be Published
7MZ1
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Structure of human DNA polymerase beta complexed with dzA in the template base paired with incoming non-hydrolyzable TTP
分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(4DU)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Koag, M.-C, Lee, S.
登録日2021-05-23
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.175 Å)
主引用文献Structure of human DNA polymerase beta complexed with dzA in the template base paired with incoming non-hydrolyzable TTP
To Be Published
7MZ4
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Structure of human DNA polymerase beta complexed with 3-deaza-3-methyladenine (3dMeA) in the template base paired with incoming dTTP
分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(DZM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Koag, M.-C, Lee, S.
登録日2021-05-24
公開日2022-06-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.076 Å)
主引用文献Structure of human DNA polymerase beta complexed with 3-deaza-3-methyladenine (3dMeA) in the template base paired with incoming dTTP
To Be Published
7MZ8
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Structure of human DNA polymerase beta complexed with 3-deaza-3-methyladenine (3dMeA) at N-1 of the template base paired with incoming dTTP
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*GP*(DZM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3'), ...
著者Koag, M.-C, Lee, S.
登録日2021-05-24
公開日2022-06-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure Of Human Dna Polymerase Beta Complexed With 8Oa As The Template Base In A 1-Nucleotide Gapped Dna
To Be Published
5Z3V
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Structure of Snf2-nucleosome complex at shl-2 in ADP BeFx state
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (167-MER), ...
著者Li, M, Xia, X, Liu, X, Li, X, Chen, Z.
登録日2018-01-08
公開日2019-05-22
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.22 Å)
主引用文献Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
5Z3O
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Structure of Snf2-nucleosome complex in ADP state
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (167-MER), Histone H2A, ...
著者Li, M, Xia, X, Liu, X, Li, X, Chen, Z.
登録日2018-01-08
公開日2019-04-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
5Z3U
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Structure of Snf2-nucleosome complex at shl2 in ADP BeFx state
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (167-MER), ...
著者Li, M, Xia, X, Liu, X, Li, X, Chen, Z.
登録日2018-01-08
公開日2019-05-22
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.31 Å)
主引用文献Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
3CMY
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Structure of a homeodomain in complex with DNA
分子名称: 1,2-ETHANEDIOL, 5'-D(*DAP*DCP*DAP*DTP*DAP*DAP*DP*DCP*DGP*DAP*DTP*DTP*DAP*DC)-3', 5'-D(*DTP*DGP*DTP*DAP*DAP*DTP*DCP*DGP*DAP*DTP*DTP*DAP*DTP*DG)-3', ...
著者Birrane, G, Ladias, J.A.A, Soni, A.
登録日2008-03-24
公開日2009-02-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Basis for DNA Recognition by the Human PAX3 Homeodomain.
Biochemistry, 48, 2009
2ISZ
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Crystal structure of a two-domain IdeR-DNA complex crystal form I
分子名称: Iron-dependent repressor ideR, NICKEL (II) ION, SODIUM ION, ...
著者Wisedchaisri, G, Chou, C.J, Wu, M, Roach, C, Rice, A.E, Holmes, R.K, Beeson, C, Hol, W.G.
登録日2006-10-18
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis
Biochemistry, 46, 2007
2IT0
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Crystal structure of a two-domain IdeR-DNA complex crystal form II
分子名称: ACETATE ION, Iron-dependent repressor ideR, NICKEL (II) ION, ...
著者Wisedchaisri, G, Chou, C.J, Wu, M, Roach, C, Rice, A.E, Holmes, R.K, Beeson, C, Hol, W.G.
登録日2006-10-18
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis
Biochemistry, 46, 2007
2A66
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Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
分子名称: 5'-D(*CP*TP*GP*GP*CP*CP*TP*TP*GP*AP*AP*C)-3', 5'-D(*GP*TP*TP*CP*AP*AP*GP*GP*CP*CP*AP*G)-3', ACETATE ION, ...
著者Solomon, I.H, Hager, J.M, Safi, R, McDonnell, D.P, Redinbo, M.R, Ortlund, E.A.
登録日2005-07-01
公開日2005-12-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Human LRH-1 DBD-DNA Complex Reveals Ftz-F1 Domain Positioning is Required for Receptor Activity.
J.Mol.Biol., 354, 2005
4QWB
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BU of 4qwb by Molmil
CRYSTAL STRUCTURE of DPO4 LINKER REGION P236A MUTANT WITH AN INCOMING D-dCDP
分子名称: ACETATE ION, CALCIUM ION, DEOXYCYTIDINE DIPHOSPHATE, ...
著者Vyas, R, Suo, Z.
登録日2014-07-16
公開日2014-08-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase.
Nucleic Acids Res., 42, 2014
6XBU
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polymerase domain of polymerase-theta
分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*GP*TP*CP*AP*TP*TP*G)-3'), DNA polymerase theta, ...
著者Chen, X, Pomerantz, R, Zhao, J.
登録日2020-06-07
公開日2021-06-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Pol theta reverse transcribes RNA and promotes RNA-templated DNA repair.
Sci Adv, 7, 2021
7MZ2
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BU of 7mz2 by Molmil
Structure of human DNA polymerase beta complexed with dzA at N-1 of the template base paired with incoming dTTP
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*GP*(4DU)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3'), ...
著者Koag, M.-C, Lee, S.
登録日2021-05-23
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.088 Å)
主引用文献Structure of human DNA polymerase beta complexed with dzA at N-1 of the template base paired with incoming dTTP
To Be Published
1NWQ
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CRYSTAL STRUCTURE OF C/EBPALPHA-DNA COMPLEX
分子名称: 5'-D(*AP*AP*AP*CP*TP*GP*GP*AP*TP*TP*GP*CP*GP*CP*AP*AP*TP*AP*GP*GP*A)-3', 5'-D(*TP*TP*CP*CP*TP*AP*TP*TP*GP*CP*GP*CP*AP*AP*TP*CP*CP*AP*GP*TP*T)-3', CCAAT/enhancer binding protein alpha
著者Miller, M, Shuman, J.D, Sebastian, T, Dauter, Z, Johnson, P.F.
登録日2003-02-06
公開日2003-05-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for DNA Recognition by the Basic Region Leucine Zipper Transcription Factor CCAAT/enhancer Binding Protein Alpha
J.Biol.Chem., 278, 2003
4A93
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RNA Polymerase II elongation complex containing a CPD Lesion
分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ...
著者Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M.
登録日2011-11-23
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
Mol.Cell, 46, 2012
1H6F
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Human TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic DNA site
分子名称: 5'-D(*TP*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP* AP*GP*GP*TP*GP*TP*GP*AP*AP*AP*T)-3', MAGNESIUM ION, T-BOX TRANSCRIPTION FACTOR TBX3
著者Coll, M, Muller, C.W.
登録日2001-06-13
公開日2002-04-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the DNA-Bound T-Box Domain of Human Tbx3, a Transcription Factor Responsible for Ulnar- Mammary Syndrome
Structure, 10, 2002
5TXZ
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DNA Polymerase Mu Reactant Complex, 100mM Mg2+ (15 min)
分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Jamsen, J.A, Wilson, S.H.
登録日2016-11-17
公開日2017-08-30
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Time-lapse crystallography snapshots of a double-strand break repair polymerase in action.
Nat Commun, 8, 2017
6ENH
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Crystal structure of the 43K ATPase domain of Thermus thermophilus gyrase B in complex with an aminocoumarin
分子名称: Coumermycin A1, DNA gyrase subunit B, IMIDAZOLE
著者Vanden Broeck, A, McEwen, A.G, Lamour, V.
登録日2017-10-04
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural Basis for DNA Gyrase Interaction with Coumermycin A1.
J.Med.Chem., 62, 2019
6ENG
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Crystal structure of the 43K ATPase domain of Escherichia coli gyrase B in complex with an aminocoumarin
分子名称: CHLORIDE ION, Coumermycin A1, DNA gyrase subunit B, ...
著者Vanden Broeck, A, McEwen, A.G, Lamour, V.
登録日2017-10-04
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for DNA Gyrase Interaction with Coumermycin A1.
J.Med.Chem., 62, 2019
1ZRF
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4 crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-[6C;17G]ICAP38 DNA
分子名称: 1,4-DIETHYLENE DIOXIDE, 5'-D(*AP*TP*TP*TP*CP*GP*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*TP*CP*GP*AP*AP*AP*T)-3', ...
著者Berman, H.M, Napoli, A.A.
登録日2005-05-19
公開日2006-03-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps.
J.Mol.Biol., 357, 2006
1ZRE
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4 crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-[6G;17C]ICAP38 DNA
分子名称: 5'-D(*AP*TP*TP*TP*CP*GP*AP*AP*AP*AP*AP*TP*GP*GP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*CP*CP*AP*TP*TP*TP*TP*TP*CP*GP*AP*AP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
著者Berman, H.M, Napoli, A.A.
登録日2005-05-19
公開日2006-03-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps.
J.Mol.Biol., 357, 2006

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件を2024-10-02に公開中

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