6ENH
Crystal structure of the 43K ATPase domain of Thermus thermophilus gyrase B in complex with an aminocoumarin
Summary for 6ENH
Entry DOI | 10.2210/pdb6enh/pdb |
Descriptor | DNA gyrase subunit B, Coumermycin A1, IMIDAZOLE, ... (4 entities in total) |
Functional Keywords | topoisomerase, gyrase b-aminocoumarin complex, isomerase |
Biological source | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) |
Total number of polymer chains | 1 |
Total formula weight | 44249.01 |
Authors | Vanden Broeck, A.,McEwen, A.G.,Lamour, V. (deposition date: 2017-10-04, release date: 2019-04-10, Last modification date: 2024-01-17) |
Primary citation | Vanden Broeck, A.,McEwen, A.G.,Chebaro, Y.,Potier, N.,Lamour, V. Structural Basis for DNA Gyrase Interaction with Coumermycin A1. J.Med.Chem., 62:4225-4231, 2019 Cited by PubMed: 30920824DOI: 10.1021/acs.jmedchem.8b01928 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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