1H6F
Human TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic DNA site
Summary for 1H6F
Entry DOI | 10.2210/pdb1h6f/pdb |
Descriptor | T-BOX TRANSCRIPTION FACTOR TBX3, 5'-D(*TP*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP* AP*GP*GP*TP*GP*TP*GP*AP*AP*AP*T)-3', MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | transcription factor, tbx3, t-box transcription factor, ulnar-mammary syndrome, holt-oram-syndrome, ig-fold, dna-binding, repressor, nuclear protein, developmental protein |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus : O15119 |
Total number of polymer chains | 4 |
Total formula weight | 60156.62 |
Authors | Coll, M.,Muller, C.W. (deposition date: 2001-06-13, release date: 2002-04-19, Last modification date: 2023-12-13) |
Primary citation | Coll, M.,Seidman, J.G.,Muller, C.W. Structure of the DNA-Bound T-Box Domain of Human Tbx3, a Transcription Factor Responsible for Ulnar- Mammary Syndrome Structure, 10:343-, 2002 Cited by PubMed: 12005433DOI: 10.1016/S0969-2126(02)00722-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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