Crystal Structure of a Ternary SAP-1/SRF/c-fos SRE DNA Complex

Summary for 1K6O

Descriptor5'-D(*CP*AP*CP*AP*GP*GP*AP*TP*GP*TP*CP*CP*AP*TP*AP*TP*TP*AP*GP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*CP*TP*AP*AP*TP*AP*TP*GP*GP*AP*CP*AP*TP*CP*CP*TP*GP*TP*G)-3', ETS-domain protein ELK-4, ... (4 entities in total)
Functional Keywordsprotein-dna complex, transcription factor, combinatorial gene regulation, ets proteins, mads-box proteins, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus P28324 P11831
Total number of polymer chains5
Total molecular weight48446.24
Mo, Y.,Ho, W.,Johnston, K.,Marmorstein, R. (deposition date: 2001-10-16, release date: 2002-01-17, Last modification date: 2018-01-31)
Primary citation
Mo, Y.,Ho, W.,Johnston, K.,Marmorstein, R.
Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex.
J.Mol.Biol., 314:495-506, 2001
PubMed: 11846562 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.2001.5138
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers252.4%5.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution