1K6O
Crystal Structure of a Ternary SAP-1/SRF/c-fos SRE DNA Complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
| A | 0043565 | molecular_function | sequence-specific DNA binding |
| B | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| B | 0000987 | molecular_function | cis-regulatory region sequence-specific DNA binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| B | 0046983 | molecular_function | protein dimerization activity |
| C | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| C | 0000987 | molecular_function | cis-regulatory region sequence-specific DNA binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| C | 0046983 | molecular_function | protein dimerization activity |
Functional Information from PROSITE/UniProt
| site_id | PS00345 |
| Number of Residues | 9 |
| Details | ETS_DOMAIN_1 Ets-domain signature 1. LWQFLLQLL |
| Chain | Residue | Details |
| A | LEU307-LEU315 |
| site_id | PS00346 |
| Number of Residues | 16 |
| Details | ETS_DOMAIN_2 Ets-domain signature 2. KpnMnYDkLSRALRyY |
| Chain | Residue | Details |
| A | LYS351-TYR366 |
| site_id | PS00350 |
| Number of Residues | 55 |
| Details | MADS_BOX_1 MADS-box domain signature. RvKikmefIdNklrRytTFsKRKtgImKKAyELStLtgtqVlLLVasetghVytF |
| Chain | Residue | Details |
| B | ARG143-PHE197 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | DNA binding: {"description":"ETS","evidences":[{"source":"PROSITE-ProRule","id":"PRU00237","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 120 |
| Details | Domain: {"description":"MADS-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00251","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
