4A93

RNA Polymerase II elongation complex containing a CPD Lesion

Summary for 4A93

Related1TWC 4A3K 1Y77 1R9S 1TWG 1SFO 4A3F 1I50 4A3D 1R5U 1DZF 4A3E 1Y14 1Y1W 1NT9 1I3Q 1TWF 1PQV 4A3G 4A3C 4A3I 1I6H 4A3B 1Y1V 1Y1Y 1WCM 4A3M 1TWA 1NIK 2VUM 1TWH 1R9T 2JA7 2JA6 4A3L 1A1D 1K83 2B63 2B8K 2JA5 4A3J 2JA8
DescriptorDNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, ... (17 entities in total)
Functional Keywordstranscription, transcription fidelity, transcription coupled dna repair, dna damage, dna repair, pyrimidine dimers
Biological sourceSACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
Total number of polymer chains15
Total molecular weight530612.82
Authors
Walmacq, C.,Cheung, A.C.M.,Kireeva, M.L.,Lubkowska, L.,Ye, C.,Gotte, D.,Strathern, J.N.,Carell, T.,Cramer, P.,Kashlev, M. (deposition date: 2011-11-23, release date: 2012-03-21, Last modification date: 2019-01-30)
Primary citation
Walmacq, C.,Cheung, A.C.,Kireeva, M.L.,Lubkowska, L.,Ye, C.,Gotte, D.,Strathern, J.N.,Carell, T.,Cramer, P.,Kashlev, M.
Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
Mol.Cell, 46:18-, 2012
PubMed: 22405652 (PDB entries with the same primary citation)
DOI: 10.1016/J.MOLCEL.2012.02.006
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.20217 3.6% 14.3% 1.8% 0.45MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution