PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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1MF8	Crystal Structure of human calcineurin complexed with cyclosporin A and human cyclophilin 分子名称: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CALMODULIN-DEPENDENT CALCINEURIN A SUBUNIT, ... 著者 Jin, L, Harrison, S.C. 登録日 2002-08-09 公開日 2002-10-16 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal Structure of Human Calcineurin Complexed with Cyclosporin a and Human Cyclophilin Proc.Natl.Acad.Sci.USA, 99, 2002
4XAH	X-ray crystal structure of S. cerevisiae Cgi121 分子名称: EKC/KEOPS complex subunit CGI121 著者 Zhang, W, Graille, M, Collinet, B, van Tilbeurgh, H. 登録日 2014-12-14 公開日 2015-03-18 最終更新日 2015-04-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex. Nucleic Acids Res., 43, 2015
3FQJ	Crystal Structure of the Mouse Dom3Z in Complex with GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein Dom3Z 著者 Xiang, S, Tong, L. 登録日 2009-01-07 公開日 2009-02-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.623 Å) 主引用文献 Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1. Nature, 458, 2009
7WJV	Crystal structure of human liver FBPase complexed with an covalent inhibitor 分子名称: 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ... 著者 Cao, H, Huang, Y, Ren, Y, Wan, J. 登録日 2022-01-08 公開日 2022-07-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.724 Å) 主引用文献 N -Acylamino Saccharin as an Emerging Cysteine-Directed Covalent Warhead and Its Application in the Identification of Novel FBPase Inhibitors toward Glucose Reduction. J.Med.Chem., 65, 2022
3O2T	Crystal structure of the N-terminal domain of human Symplekin 分子名称: 1,2-ETHANEDIOL, Symplekin 著者 Tong, L, Xiang, K, Xiang, S. 登録日 2010-07-22 公開日 2010-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature, 467, 2010
3ODR	Crystal Structure of the N-terminal Domain of Human Symplekin 分子名称: 1,2-ETHANEDIOL, Symplekin 著者 Tong, L, Xiang, K. 登録日 2010-08-11 公開日 2010-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature, 467, 2010
8AT6	Cryo-EM structure of yeast Elp456 subcomplex 分子名称: Elongator complex protein 4, Elongator complex protein 5, Elongator complex protein 6 著者 Jaciuk, M, Scherf, D, Kaszuba, K, Gaik, M, Koscielniak, A, Krutyholowa, R, Rawski, M, Indyka, P, Biela, A, Dobosz, D, Lin, T.-Y, Abbassi, N, Hammermeister, A, Chramiec-Glabik, A, Kosinski, J, Schaffrath, R, Glatt, S. 登録日 2022-08-22 公開日 2022-12-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structure of the fully assembled Elongator complex. Nucleic Acids Res., 51, 2023
8ASV	Cryo-EM structure of yeast Elongator complex 分子名称: Elongator complex protein 1, Elongator complex protein 2, Elongator complex protein 3, ... 著者 Jaciuk, M, Scherf, D, Kaszuba, K, Gaik, M, Koscielniak, A, Krutyholowa, R, Rawski, M, Indyka, P, Biela, A, Dobosz, D, Lin, T.-Y, Abbassi, N, Hammermeister, A, Chramiec-Glabik, A, Kosinski, J, Schaffrath, R, Glatt, S. 登録日 2022-08-21 公開日 2022-12-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.35 Å) 主引用文献 Cryo-EM structure of the fully assembled Elongator complex. Nucleic Acids Res., 51, 2023
6DMG	A multiconformer ligand model of EK6 bound to ERK2 分子名称: 1,2-ETHANEDIOL, Mitogen-activated protein kinase 1, SULFATE ION, ... 著者 Hudson, B.M, van Zundert, G.C.P, Keedy, D.A, Fonseca, R, Heliou, A, Suresh, P, Borrelli, K, Day, T, Fraser, J.S, van den Bedem, H. 登録日 2018-06-05 公開日 2018-12-19 最終更新日 2019-04-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 qFit-ligand Reveals Widespread Conformational Heterogeneity of Drug-Like Molecules in X-Ray Electron Density Maps. J. Med. Chem., 61, 2018
5OP0	Structure of Prim-PolC from Mycobacterium smegmatis 分子名称: DNA polymerase LigD, polymerase domain 著者 Brissett, N.C, Doherty, A.J. 登録日 2017-08-09 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria. Nat Commun, 8, 2017
4L0Y	Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 1) 分子名称: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Protein C-ets-1, ... 著者 Tahirov, T.H. 登録日 2013-06-01 公開日 2014-03-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of Ets1 activation by Runx1. Leukemia, 28, 2014
4L18	Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 3) 分子名称: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', GLYCEROL, ... 著者 Tahirov, T.H. 登録日 2013-06-02 公開日 2014-03-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of Ets1 activation by Runx1. Leukemia, 28, 2014
8HST	The structure of rat beta-arrestin1 分子名称: Beta-arrestin-1 著者 Yun, Y, Yoon, H.J, Choi, Y, Lee, H.H. 登録日 2022-12-20 公開日 2023-07-19 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 GPCR targeting of E3 ubiquitin ligase MDM2 by inactive beta-arrestin. Proc.Natl.Acad.Sci.USA, 120, 2023
8HSV	The structure of rat beta-arrestin1 in complex with a rat Mdm2 peptide 分子名称: Beta-arrestin-1, SULFATE ION, peptide from E3 ubiquitin-protein ligase Mdm2 著者 Yun, Y, Yoon, H.J, Choi, Y, Lee, H.H. 登録日 2022-12-20 公開日 2023-07-19 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 GPCR targeting of E3 ubiquitin ligase MDM2 by inactive beta-arrestin. Proc.Natl.Acad.Sci.USA, 120, 2023
4L0Z	Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 2) 分子名称: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Protein C-ets-1, ... 著者 Tahirov, T.H. 登録日 2013-06-01 公開日 2014-03-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of Ets1 activation by Runx1. Leukemia, 28, 2014
3KQK	Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism 分子名称: 5'-D(*TP*TP*TP*TP*TP*T)-3', Serine protease/NTPase/helicase NS3 著者 Gu, M, Rice, C.M. 登録日 2009-11-17 公開日 2010-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism. Proc.Natl.Acad.Sci.USA, 107, 2010
3E93	Crystal Structure of P38 Kinase in Complex with A Biaryl Amide Inhibitor 分子名称: 4-methyl-N-(3-morpholin-4-ylphenyl)-3-(3-piperidin-4-yl-1,2-benzisoxazol-6-yl)benzamide, GLYCEROL, Mitogen-activated protein kinase 14 著者 Somers, D.O, Patel, S. 登録日 2008-08-21 公開日 2008-09-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Kinase array design, back to front: Biaryl amides Bioorg.Med.Chem.Lett., 18, 2008
3E92	Crystal Structure of P38 Kinase in Complex with A Biaryl Amide Inhibitor 分子名称: GLYCEROL, Mitogen-activated protein kinase 14, N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide 著者 Somers, D.O, Patel, S. 登録日 2008-08-21 公開日 2008-09-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Kinase array design, back to front: Biaryl amides Bioorg.Med.Chem.Lett., 18, 2008
8JRV	Cryo-EM structure of the glucagon receptor bound to glucagon and beta-arrestin 1 分子名称: Beta-arrestin 1 and single-chain fragment variable 30 (scFv30), Glucagon, HA signal peptide,HPC4 purification tag,Glucagon receptor,C-terminal tail of Vasopressin V2 receptor, ... 著者 Chen, K, Zhang, C, Lin, S, Zhao, Q, Wu, B. 登録日 2023-06-17 公開日 2023-08-16 最終更新日 2023-09-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Tail engagement of arrestin at the glucagon receptor. Nature, 620, 2023
5E0U	Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms 分子名称: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen 著者 Duffy, C.M, Hilbert, B.J, Kelch, B.A. 登録日 2015-09-29 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428, 2016
5E0T	Human PCNA mutant - S228I 分子名称: Proliferating cell nuclear antigen 著者 Duffy, C.M, Hilbert, B.J, Kelch, B.A. 登録日 2015-09-29 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6653 Å) 主引用文献 A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428, 2016
6KDM	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:entecavir 5'-triphosphate ternary complex 分子名称: DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... 著者 Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. 登録日 2019-07-02 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
3OUO	Structure of the Nucleoprotein from Rift Valley Fever Virus 分子名称: NITRITE ION, Nucleoprotein 著者 Ferron, F, Danek, E.I, Li, Z, Luo, D, Wong, Y.H, Coutard, B, Lantez, V, Charrel, R, Canard, B, Walz, T, Lescar, J. 登録日 2010-09-15 公開日 2011-05-25 最終更新日 2013-08-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes Plos Pathog., 7, 2011
6UIS	HIV-1 M184V reverse transcriptase-DNA complex with dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Primer DNA, ... 著者 Lansdon, E.B. 登録日 2019-10-01 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.74833822 Å) 主引用文献 Elucidating molecular interactions ofL-nucleotides with HIV-1 reverse transcriptase and mechanism of M184V-caused drug resistance. Commun Biol, 2, 2019
6KDK	HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dCTP ternary complex 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... 著者 Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. 登録日 2019-07-02 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020

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