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2PC2
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Lysozyme Cocrystallized with Tris-dipicolinate Eu complex
分子名称: CHLORIDE ION, EUROPIUM ION, Lysozyme C, ...
著者Pompidor, G, Vicat, J, Kahn, R.
登録日2007-03-29
公開日2008-04-01
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.538 Å)
主引用文献A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction
Acta Crystallogr.,Sect.D, 66, 2010
2OZ5
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BU of 2oz5 by Molmil
Crystal structure of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB in complex with the specific inhibitor OMTS
分子名称: Phosphotyrosine protein phosphatase ptpb, {(3-CHLOROBENZYL)[(5-{[(3,3-DIPHENYLPROPYL)AMINO]SULFONYL}-2-THIENYL)METHYL]AMINO}(OXO)ACETIC ACID
著者Grundner, C, Gee, C.L, Alber, T, TB Structural Genomics Consortium (TBSGC)
登録日2007-02-23
公開日2007-05-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB.
Structure, 15, 2007
2PE7
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Thaumatin from Thaumatococcus Danielli in complex with tris-dipicolinate Europium
分子名称: EUROPIUM ION, L(+)-TARTARIC ACID, PYRIDINE-2,6-DICARBOXYLIC ACID, ...
著者Pompidor, G, Vicat, J, Kahn, R.
登録日2007-04-02
公開日2008-04-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction.
Acta Crystallogr.,Sect.D, 66, 2010
2PEK
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Crystal structure of RbcX point mutant Q29A
分子名称: ORF134
著者Saschenbrecker, S, Bracher, A, Vasudeva Rao, K, Vasudeva Rao, B, Hartl, F.U, Hayer-Hartl, M.
登録日2007-04-03
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2PF0
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F258I mutant of EXO-B-(1,3)-GLUCANASE FROM CANDIDA ALBICANS at 1.9 A
分子名称: Hypothetical protein XOG1
著者Cutfield, S.M, Cutfield, J.F, Patrick, W.M.
登録日2007-04-03
公開日2008-04-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Carbohydrate binding sites in Candida albicans exo-beta-1,3-glucanase and the role of the Phe-Phe 'clamp' at the active site entrance.
Febs J., 277, 2010
1M01
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BU of 1m01 by Molmil
Wildtype Streptomyces plicatus beta-hexosaminidase in complex with product (GlcNAc)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, CHLORIDE ION, ...
著者J Williams, S, Mark, B.L, Vocadlo, D.J, James, M.N.G, Withers, S.G.
登録日2002-06-11
公開日2003-01-21
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state.
J.Biol.Chem., 277, 2002
2P2V
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Crystal structure analysis of monofunctional alpha-2,3-sialyltransferase Cst-I from Campylobacter jejuni
分子名称: 1,2-ETHANEDIOL, Alpha-2,3-sialyltransferase, CHLORIDE ION, ...
著者Chiu, C.P, Lairson, L.L, Gilbert, M, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.
登録日2007-03-07
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Analysis of the alpha-2,3-Sialyltransferase Cst-I from Campylobacter jejuni in Apo and Substrate-Analogue Bound Forms.
Biochemistry, 46, 2007
2P3H
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Crystal structure of the CorC_HlyC domain of a putative Corynebacterium glutamicum hemolysin
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, Uncharacterized CBS domain-containing protein
著者Cuff, M.E, Volkart, L, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-03-08
公開日2007-04-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the CorC_HlyC domain of a putative Corynebacterium glutamicum hemolysin.
TO BE PUBLISHED
2P59
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Crystal Structure of Hepatitis C Virus NS3.4A protease
分子名称: (2S,3AS,7AS)-1-[(2S)-2-{[(2S)-2-CYCLOHEXYL-2-({[(2R)-4-NITRO-2H-PYRROL-2-YL]CARBONYL}AMINO)ACETYL]AMINO}-3,3-DIMETHYLBUTANOYL]-N-{(1S)-1-[(1R)-2-(CYCLOPROPYLAMINO)-1-HYDROXY-2-OXOETHYL]BUTYL}OCTAHYDRO-1H-INDOLE-2-CARBOXAMIDE, NS3, peptide
著者Perni, R.B, Wei, Y.
登録日2007-03-14
公開日2008-02-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics.
Bioorg.Med.Chem.Lett., 17, 2007
2P5M
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C-terminal domain hexamer of AhrC bound with L-arginine
分子名称: ARGININE, Arginine repressor
著者Garnett, J.A, Baumberg, S, Stockley, P.G, Phillips, S.E.V.
登録日2007-03-15
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of the C-terminal effector-binding domain of AhrC bound to its corepressor L-arginine.
Acta Crystallogr.,Sect.F, 63, 2007
2P5Y
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Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase
著者Fu, Z.-Q, Chen, L, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhu, J, Swindell, J.T, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-16
公開日2007-04-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD
To be Published
2P6A
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BU of 2p6a by Molmil
The structure of the Activin:Follistatin 315 complex
分子名称: Follistatin, Inhibin beta A chain, probable fragment of follistatin
著者Lerch, T.F, Shimasaki, S, Woodruff, T.K, Jardetzky, T.S.
登録日2007-03-16
公開日2007-04-03
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions.
J.Biol.Chem., 282, 2007
2P6R
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Crystal structure of superfamily 2 helicase Hel308 in complex with unwound DNA
分子名称: 25-MER, 5'-D(*CP*TP*AP*GP*AP*GP*AP*CP*TP*AP*TP*CP*GP*AP*T)-3', afUHEL308 HELICASE
著者Buettner, K, Nehring, S, Hopfner, K.P.
登録日2007-03-19
公開日2007-06-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for DNA duplex separation by a superfamily-2 helicase.
Nat.Struct.Mol.Biol., 14, 2007
2P5W
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BU of 2p5w by Molmil
Crystal structures of high affinity human T-cell receptors bound to pMHC reveal native diagonal binding geometry
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, CALCIUM ION, ...
著者Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K.
登録日2007-03-16
公開日2007-09-25
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Protein Eng.Des.Sel., 20, 2007
8PWH
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Atomic structure and conformational variability of the HER2-Trastuzumab-Pertuzumab complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, Pertuzumab Fab light chain, ...
著者Ruedas, R, Vuillemot, R, Tubiana, T, Winter, J.M, Pieri, L, Arteni, A.A, Samson, C, Jonic, J, Mathieu, M, Bressanelli, S.
登録日2023-07-20
公開日2024-02-21
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex.
J.Struct.Biol., 216, 2024
2P6Z
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Enzymatic and Structural Characterisation of Amphinase, a Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes
分子名称: CITRIC ACID, Recombinant Amphinase-2, SODIUM ION
著者Singh, U.P.
登録日2007-03-19
公開日2007-05-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Enzymatic and Structural Characterisation of Amphinase, a Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes.
J.Mol.Biol., 371, 2007
2P83
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Potent and selective isophthalamide S2 hydroxyethylamine inhibitor of BACE1
分子名称: Beta-secretase 1, N~3~-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-N~1~,N~1~-DIPROPYLBENZENE-1,3,5-TRICARBOXAMIDE, PHOSPHATE ION
著者Benson, T.E, Prince, D.B, Tomasselli, A.G, Emmons, T.L, Paddock, D.J.
登録日2007-03-21
公開日2007-06-19
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Potent and selective isophthalamide S(2) hydroxyethylamine inhibitors of BACE1.
Bioorg.Med.Chem.Lett., 17, 2007
2P8V
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Crystal structure of human Homer3 EVH1 domain
分子名称: Homer protein homolog 3, SULFATE ION
著者Bouyain, S, Tu, J, Huang, G.N, Worley, P.F, Leahy, D.
登録日2007-03-23
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.
Science, 319, 2008
2P93
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Factor xa in complex with the inhibitor 5-chloro-N-(2-(4-(2-oxopyridin-1(2H)-yl)benzamido)ethyl)thiophene-2-carboxamide
分子名称: 5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE, Factor Xa
著者Chang, C.-H.
登録日2007-03-23
公開日2007-07-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa
Bioorg.Med.Chem.Lett., 17, 2007
2P8R
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Crystal structure of the C-terminal domain of C. elegans pre-mRNA splicing factor Prp8 carrying R2303K mutant
分子名称: Pre-mRNA-splicing factor Prp8
著者Zhang, L, Shen, J, Guarnieri, M.T, Heroux, A, Yang, K, Zhao, R.
登録日2007-03-22
公開日2007-05-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants
Protein Sci., 16, 2007
2P94
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Factor xa in complex with the inhibitor 3-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)benzamido)cyclohexyl)-1H-indole-6-carboxamide
分子名称: 3-CHLORO-N-((1R,2S) -2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)CYCLOHEXYL)-1H-INDOLE-6-CARBOXAMIDE, Factor Xa
著者Chang, C.-H.
登録日2007-03-23
公開日2007-07-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa
Bioorg.Med.Chem.Lett., 17, 2007
2P9T
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Crystal Structure of Phosphoglycerate Kinase-2 bound to 3-phosphoglycerate
分子名称: 3-PHOSPHOGLYCERIC ACID, Phosphoglycerate kinase, testis specific
著者Sawyer, G.M, Monzingo, A.F, Poteet, E.C, Robertus, J.D.
登録日2007-03-26
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray analysis of phosphoglycerate kinase 2, a sperm-specific isoform from Mus musculus.
Proteins, 71, 2007
8ID7
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Crystal structure of YbiW in complex with 1,5-anhydroglucitol-6-phosphate in Escherichia coli
分子名称: 1,5-anhydro-6-O-phosphono-D-glucitol, Probable dehydratase YbiW
著者Ma, K.L, Zhang, Y.
登録日2023-02-12
公開日2024-10-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A Widespread Radical-Mediated Glycolysis Pathway.
J.Am.Chem.Soc., 146, 2024
2P9A
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E. coli methionine aminopeptidase dimetalated with inhibitor YE6
分子名称: 5-(2-chlorophenyl)furan-2-carbohydrazide, MANGANESE (II) ION, Methionine aminopeptidase, ...
著者Ye, Q.
登録日2007-03-24
公開日2007-11-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inhibition of Monometalated Methionine Aminopeptidase: Inhibitor Discovery and Crystallographic Analysis.
J.Med.Chem., 50, 2007
2PBI
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The multifunctional nature of Gbeta5/RGS9 revealed from its crystal structure
分子名称: GLYCEROL, Guanine nucleotide-binding protein subunit beta 5, Regulator of G-protein signaling 9
著者Cheever, M.L, Snyder, J.T, Gershburg, S, Siderovski, D.P, Harden, T.K, Sondek, J.
登録日2007-03-28
公開日2008-01-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the multifunctional Gbeta5-RGS9 complex.
Nat.Struct.Mol.Biol., 15, 2008

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