PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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7QWJ	Crystal structure of Glc7 phosphatase 分子名称: MANGANESE (II) ION, PHOSPHATE ION, Serine/threonine-protein phosphatase PP1-2 著者 Malhotra, K, Carminati, M, Bertolotti, A, Bellini, D. 登録日 2022-01-25 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of Glc7 phosphatase To Be Published
7QWV	Crystal structure of the REC114-TOPOVIBL complex. 分子名称: Meiotic recombination protein REC114, Type 2 DNA topoisomerase 6 subunit B-like 著者 Juarez-Martinez, A.B, Robert, T, de Massy, B, Kadlec, J. 登録日 2022-01-25 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 TOPOVIBL-REC114 interaction regulates meiotic DNA double-strand breaks. Nat Commun, 13, 2022
6KNE	The C-terminal Domain of Translation Initiation Factor 5 at high pH 分子名称: Translation initiation factor eIF5 著者 Jian, Y, YuXin, Y, Min, Y. 登録日 2019-08-05 公開日 2020-06-17 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 The pH-dependent conformational change of eukaryotic translation initiation factor 5: Insights into partner-binding manner. Biochem.Biophys.Res.Commun., 519, 2019
7LLY	Oxyntomodulin-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein 分子名称: Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Wootten, D, Sexton, P.M, Belousoff, M.J, Danev, R, Zhang, X, Khoshouei, M, Venugopal, H. 登録日 2021-02-04 公開日 2022-01-12 最終更新日 2022-01-26 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation. Nat Commun, 13, 2022
7QVJ	ESTROGEN RECEPTOR ALPHA IN COMPLEX WITH COMPOUND 29 分子名称: 2,2-bis(fluoranyl)-3-[(1~{R},3~{R})-1-[6-fluoranyl-3-[2-(3-fluoranylpropylamino)ethoxy]-2-methyl-phenyl]-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]propan-1-ol, Estrogen receptor 著者 Breed, J. 登録日 2022-01-21 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists. J.Med.Chem., 66, 2023
1MQM	BHA/LSTa 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... 著者 ha, y, steven, d.j, skehel, j.j, wiley, d.c. 登録日 2002-09-16 公開日 2003-08-26 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus. Virology, 309, 2003
7LC7	Crystal structure of epoxyqueuosine reductase QueH in complex with GMP from Thermotoga maritima 分子名称: CHLORIDE ION, Epoxyqueuosine reductase QueH, FE (III) ION, ... 著者 Li, Q, Bruner, S.D. 登録日 2021-01-09 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 The epoxyqueuosine reductase QueH in the biosynthesis of tRNA queuosine is a unique metalloenzyme To Be Published
3UG2	Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in complex with gefitinib 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, Gefitinib 著者 Parker, L.J, Handa, N, Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. 登録日 2011-11-02 公開日 2012-03-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor Oncogene, 32, 2013
7LBX	Crystal structure of TFAM (mitochondrial transcription factor A) in complex with LSP 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(P*TP*TP*AP*AP*CP*AP*GP*TP*CP*AP*CP*CP*CP*CP*CP*CP*AP*AP*CP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*GP*TP*TP*GP*GP*GP*GP*GP*GP*TP*GP*AP*CP*TP*GP*TP*TP*AP*A)-3'), ... 著者 Choi, W.S, Garcia-Diaz, M. 登録日 2021-01-09 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A minimal motif for sequence recognition by mitochondrial transcription factor A (TFAM). Nucleic Acids Res., 50, 2022
7LBW	Crystal structure of TFAM (mitochondrial transcription factor A) bridging two non-sequence specific DNA substrates 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(P*TP*AP*GP*CP*CP*TP*TP*TP*CP*TP*AP*TP*TP*AP*GP*CP*TP*CP*TP*TP*AP*G)-3'), ... 著者 Choi, W.S, Garcia-Diaz, M. 登録日 2021-01-09 公開日 2022-01-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 A minimal motif for sequence recognition by mitochondrial transcription factor A (TFAM). Nucleic Acids Res., 50, 2022
7QZJ	1.55 A X-ray crystallographic structure of SapH from Streptomyces sp. (HPH0547) involved in Pseudouridimycin biosynthesis 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase family protein, GLYCEROL, ... 著者 Schnell, R, Schneider, G. 登録日 2022-01-31 公開日 2023-02-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Pseudouridine-Modifying Enzymes SapB and SapH Control Entry into the Pseudouridimycin Biosynthetic Pathway. Acs Chem.Biol., 18, 2023
1MN2	MANGANESE PEROXIDASE SUBSTRATE BINDING SITE MUTANT E35Q, D179N 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MANGANESE PEROXIDASE, ... 著者 Sundaramoorthy, M, Poulos, T.L. 登録日 1997-04-26 公開日 1997-09-04 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of substrate binding site mutants of manganese peroxidase. J.Biol.Chem., 272, 1997
4W4V	JNK2/3 in complex with 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide 分子名称: 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide, c-Jun N-terminal kinase 3 著者 Park, H, Iqbal, S, Hernandez, P, Mora, R, Zheng, K, Feng, Y, LoGrasso, P. 登録日 2014-08-15 公開日 2015-02-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles. Sci Rep, 5, 2015
7QXF	Fructose-6-phosphate aldolase (FSA) mutant R134V, S166G, with covalently bound active site ligand 分子名称: Fructose-6-phosphate aldolase 1 著者 Dobritzsch, D, Widersten, M, Engel, S. 登録日 2022-01-26 公開日 2023-02-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Engineered aldolases catalyzing stereoselective aldol reactions between aryl-substituted ketones and aldehydes Catalysis Science And Technology, 13, 2023
4W4Y	JNK2/3 in complex with 3-(4-{[(4-methylphenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide 分子名称: 3-(4-{[(4-methylphenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide, c-jun NH2-terminal kinase 3 著者 Park, H, Iqbal, S, Hernandez, P, Mora, R, Zheng, K, Feng, Y, LoGrasso, P. 登録日 2014-08-15 公開日 2015-02-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles. Sci Rep, 5, 2015
7LY5	Proteolyzed crystal structure of the bacillamide NRPS, BmdB, in complex with the oxidase BmdC 分子名称: BmdB, Bacillamide NRPS, BmdC, ... 著者 Fortinez, C.M, Schmeing, T.M. 登録日 2021-03-05 公開日 2022-02-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nat Commun, 13, 2022
4W5A	Complex structure of ATRX ADD bound to H3K9me3S10ph peptide 分子名称: Peptide from Histone H3.3, Transcriptional regulator ATRX, ZINC ION 著者 Zhao, D, Xiang, B, Li, H. 登録日 2014-08-17 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons Proc.Natl.Acad.Sci.USA, 112, 2015
7QOM	A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability 分子名称: CHLORIDE ION, COBALT (II) ION, Nitrile hydratase, ... 著者 Van Wyk, J.C, Cowan, D.A, Danson, M.J, Tsekoa, T.L, Sayed, M.F, Sewell, B.T. 登録日 2022-03-17 公開日 2023-03-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability To be published
4W65	Crystal Structure of Glycosyl hydrolase family protein from Mycobacterium fortuitum 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Glycosyl hydrolase family protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-08-20 公開日 2014-09-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Crystal Structure of Glycosyl hydrolase family protein (Rv0315 ortholog) from Mycobacterium fortuitum TO BE PUBLISHED
4W8F	Crystal structure of the dynein motor domain in the AMPPNP-bound state 分子名称: Dynein heavy chain lysozyme chimera, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Cheng, H.-C, Bhabha, G, Zhang, N, Vale, R.D. 登録日 2014-08-24 公開日 2014-11-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.541 Å) 主引用文献 Allosteric communication in the Dynein motor domain. Cell, 159, 2014
7LY6	Structure of a trans-acting NRPS oxidase, BmdC, involved in bacillamide biosynthesis 分子名称: BmdC, NRPS oxidase, FLAVIN MONONUCLEOTIDE, ... 著者 Fortinez, C.M, Bloudoff, K, Schmeing, T.M. 登録日 2021-03-05 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nat Commun, 13, 2022
4UUY	Structural Identification of the Vps18 beta-propeller reveals a critical role in the HOPS complex stability and function. 分子名称: 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... 著者 Behrmann, H, Gohlke, U, Heinemann, U. 登録日 2014-08-01 公開日 2014-10-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structural Identification of the Vps18 Beta-Propeller Reveals a Critical Role in the Hops Complex Stability and Function. J.Biol.Chem., 289, 2014
6K5Z	Structure of uridylyltransferase 分子名称: FE (III) ION, Galactose-1-phosphate uridylyltransferase, PHOSPHATE ION, ... 著者 Sakuraba, H, Ohshida, T, Yoneda, K, Ohshima, T. 登録日 2019-05-31 公開日 2019-12-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Unique active site formation in a novel galactose 1-phosphate uridylyltransferase from the hyperthermophilic archaeon Pyrobaculum aerophilum. Proteins, 88, 2020
2G7P	Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors 分子名称: Botulinum neurotoxin type A, ZINC ION 著者 Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. 登録日 2006-02-28 公開日 2006-08-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate. Biochemistry, 45, 2006
4USF	Human SLK with SB-440719 分子名称: 4-[4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl]pyridine, STE20-LIKE SERINE/THREONINE-PROTEIN KINASE 著者 Elkins, J.M, Salah, E, Szklarz, M, von Delft, F, Bountra, C, Edwards, A.M, Knapp, S. 登録日 2014-07-07 公開日 2015-07-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Comprehensive Characterization of the Published Kinase Inhibitor Set. Nat.Biotechnol., 34, 2016

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