2P9A

E. coli methionine aminopeptidase dimetalated with inhibitor YE6

Summary for 2P9A

• Entry DOI: 10.2210/pdb2p9a/pdb
• Related: 2GTX
• Descriptor: Methionine aminopeptidase, MANGANESE (II) ION, SODIUM ION, ... (5 entities in total)
• Functional Keywords: dimetalated, dinuclear, mn(ii)-form, hydrolase, enzyme-inhibitor complex, metalloenzyme
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 29480.05

Authors

Ye, Q. (deposition date: 2007-03-24, release date: 2007-11-20, Last modification date: 2024-02-21)

• Primary citation: Huang, M.,Xie, S.X.,Ma, Z.Q.,Huang, Q.Q.,Nan, F.J.,Ye, Q.Z.; Inhibition of Monometalated Methionine Aminopeptidase: Inhibitor Discovery and Crystallographic Analysis.; J.Med.Chem., 50:5735-5742, 2007; PubMed: 17948983; DOI: 10.1021/jm700930k

Experimental method

X-RAY DIFFRACTION (1.6 Å)