4RFR
 
 | | Complex structure of AlkB/rhein | | 分子名称: | 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, Alpha-ketoglutarate-dependent dioxygenase AlkB, MANGANESE (II) ION | | 著者 | Li, Q, Huang, Y, Li, J.F, Yang, C.-G. | | 登録日 | 2014-09-27 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Rhein Inhibits AlkB Repair Enzymes and Sensitizes Cells to Methylated DNA Damage.
J.Biol.Chem., 291, 2016
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4R8W
 | | Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a neutralizing antibody CT149 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of neutralizing antibody CT149, Hemagglutinin, ... | | 著者 | Wu, Y, Shi, Y, Qi, J, Gao, G.F. | | 登録日 | 2014-09-03 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.795 Å) | | 主引用文献 | A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus
Nat Commun, 6, 2015
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7R8A
 | | The structure of human ABCG5/ABCG8 purified from mammalian cells | | 分子名称: | 2C7 Fab heavy chain, 2C7 Fab light chain, ATP-binding cassette sub-family G member 5, ... | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7R88
 | | The structure of human ABCG5-I529W/ABCG8-WT | | 分子名称: | 2C7 Fab heavy chain, 2C7 Fab light chain, ATP-binding cassette sub-family G member 5, ... | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7R8B
 | | The structure of human ABCG5/ABCG8 supplemented with cholesterol | | 分子名称: | 2C7 Fab heavy chain, 2C7 Fab light chain, ATP-binding cassette sub-family G member 5, ... | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7R89
 | | The structure of human ABCG5/ABCG8 purified from yeast | | 分子名称: | 2C7 Fab heavy chain, 2C7 Fab light chain, ATP-binding cassette sub-family G member 5, ... | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7R87
 | | The structure of human ABCG5-WT/ABCG8-I419E | | 分子名称: | 2C7 Fab heavy chain, 2C7 Fab light chain, ATP-binding cassette sub-family G member 5, ... | | 著者 | Sun, Y, Li, X, Long, T. | | 登録日 | 2021-06-26 | | 公開日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular basis of cholesterol efflux via ABCG subfamily transporters.
Proc.Natl.Acad.Sci.USA, 118, 2021
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4R6I
 | | AtxA protein, a virulence regulator from Bacillus anthracis. | | 分子名称: | Anthrax toxin expression trans-acting positive regulator, DODECYL-BETA-D-MALTOSIDE | | 著者 | Osipiuk, J, Horton, L.B, Koehler, T.M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-08-25 | | 公開日 | 2014-10-22 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal structure of Bacillus anthracis virulence regulator AtxA and effects of phosphorylated histidines on multimerization and activity.
Mol.Microbiol., 95, 2015
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4RYD
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4RNW
 | | Truncated version of the G303 Circular Permutation of Old Yellow Enzyme | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S. | | 登録日 | 2014-10-26 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.552 Å) | | 主引用文献 | STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
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5T0J
 | | Structural basis for dynamic regulation of the human 26S proteasome | | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | | 著者 | Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2016-08-16 | | 公開日 | 2016-10-19 | | 最終更新日 | 2016-11-30 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4RKD
 | | Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with aspartic acid | | 分子名称: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYLENE)-AMINO]-SUCCINIC ACID, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aromatic amino acid aminotransferase, ... | | 著者 | Bujacz, A, Rutkiewicz-Krotewicz, M, Bujacz, G, Nowakowska-Sapota, K, Turkiewicz, M. | | 登録日 | 2014-10-12 | | 公開日 | 2015-03-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Crystal structure and enzymatic properties of a broad substrate-specificity psychrophilic aminotransferase from the Antarctic soil bacterium Psychrobacter sp. B6.
Acta Crystallogr.,Sect.D, 71, 2015
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4TQN
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4RNX
 | | K154 Circular Permutation of Old Yellow Enzyme | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase 1 | | 著者 | Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S. | | 登録日 | 2014-10-26 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
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4RXY
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4RNU
 | | G303 Circular Permutation of Old Yellow Enzyme | | 分子名称: | FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase 1, PHOSPHATE ION | | 著者 | Horton, J.R, Daugherty, A.B, Cheng, X, Lutz, S. | | 登録日 | 2014-10-26 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.677 Å) | | 主引用文献 | STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF CIRCULAR PERMUTATION ON THE ACTIVE SITE OF OLD YELLOW ENZYME.
ACS Catal, 5, 2015
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4RKC
 | | Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aromatic amino acid aminotransferase, MAGNESIUM ION, ... | | 著者 | Bujacz, A, Rutkiewicz-Krotewicz, M, Bujacz, G, Nowakowska-Sapota, K, Turkiewicz, M. | | 登録日 | 2014-10-12 | | 公開日 | 2015-03-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Crystal structure and enzymatic properties of a broad substrate-specificity psychrophilic aminotransferase from the Antarctic soil bacterium Psychrobacter sp. B6.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4U0R
 | | Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody 9AD4 | | 分子名称: | Monoclonal antibody 9AD4 heavy chain, Monoclonal antibody 9AD4 light chain, Reticulocyte binding protein 5 | | 著者 | Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K. | | 登録日 | 2014-07-14 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.
Nature, 515, 2014
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4U15
 | | M3-mT4L receptor bound to tiotropium | | 分子名称: | (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, D(-)-TARTARIC ACID, ... | | 著者 | Thorsen, T.S, Matt, R, Weis, W.I, Kobilka, B. | | 登録日 | 2014-07-15 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis.
Structure, 22, 2014
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4U14
 | | Structure of the M3 muscarinic acetylcholine receptor bound to the antagonist tiotropium crystallized with disulfide-stabilized T4 lysozyme (dsT4L) | | 分子名称: | (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane, Muscarinic acetylcholine receptor M3,Endolysin,Muscarinic acetylcholine receptor M3 | | 著者 | Thorsen, T.S, Matt, R.A, Weis, W.I, Kobilka, B.K. | | 登録日 | 2014-07-15 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.57 Å) | | 主引用文献 | Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis.
Structure, 22, 2014
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4TWP
 | | The crystal structure of human abl1 T315I gatekeeper mutant kinase domain in complex with axitinib | | 分子名称: | AXITINIB, NICKEL (II) ION, SODIUM ION, ... | | 著者 | Johnson, E, McTigue, M, Cronin, C.N. | | 登録日 | 2014-07-01 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation.
Nature, 519, 2015
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5T0G
 | | Structural basis for dynamic regulation of the human 26S proteasome | | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | | 著者 | Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2016-08-16 | | 公開日 | 2016-10-19 | | 最終更新日 | 2016-11-30 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4U1G
 | | Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody QA1 | | 分子名称: | QA1 monoclonal antibody heavy chain, QA1 monoclonal antibody light chain, Reticulocyte binding protein 5 | | 著者 | Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K. | | 登録日 | 2014-07-15 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.
Nature, 515, 2014
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5T0H
 | | Structural basis for dynamic regulation of the human 26S proteasome | | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | | 著者 | Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2016-08-16 | | 公開日 | 2016-10-19 | | 最終更新日 | 2016-11-30 | | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | | 主引用文献 | Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4TOY
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