4U1G
Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody QA1
Summary for 4U1G
| Entry DOI | 10.2210/pdb4u1g/pdb |
| Descriptor | Reticulocyte binding protein 5, QA1 monoclonal antibody heavy chain, QA1 monoclonal antibody light chain (3 entities in total) |
| Functional Keywords | malaria erythrocyte invasion antibody-mediated inhibition, immune system |
| Biological source | Plasmodium falciparum More |
| Total number of polymer chains | 6 |
| Total formula weight | 234412.56 |
| Authors | Wright, K.E.,Hjerrild, K.A.,Bartlett, J.,Douglas, A.D.,Jin, J.,Brown, R.E.,Ashfield, R.,Clemmensen, S.B.,de Jongh, W.A.,Draper, S.J.,Higgins, M.K. (deposition date: 2014-07-15, release date: 2014-08-13, Last modification date: 2023-12-20) |
| Primary citation | Wright, K.E.,Hjerrild, K.A.,Bartlett, J.,Douglas, A.D.,Jin, J.,Brown, R.E.,Illingworth, J.J.,Ashfield, R.,Clemmensen, S.B.,de Jongh, W.A.,Draper, S.J.,Higgins, M.K. Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies. Nature, 515:427-430, 2014 Cited by PubMed: 25132548DOI: 10.1038/nature13715 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
Download full validation report
