PDB: 243531 件ウェブページステータス検索Chemie searchBIRD

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7M26	Human carbonic anhydrase II in complex with pioglitazone 分子名称: (5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione, Carbonic anhydrase 2, ZINC ION 著者 Mueller, S.L, Peat, T.S. 登録日 2021-03-16 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors-A Spin-Off Discovery from Fragment Screening. Molecules, 26, 2021
5VFA	RitR Mutant - C128D 分子名称: Response regulator 著者 Han, L, Silvaggi, N.R. 登録日 2017-04-07 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.452 Å) 主引用文献 RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization. PLoS Pathog., 14, 2018
5IOK	Crystal structure of Taf14 YEATS domain in complex with histone H3K9cr 分子名称: (ACE)QTAR(KCR)ST, DI(HYDROXYETHYL)ETHER, Transcription initiation factor TFIID subunit 14 著者 Andrews, F.H, Kuateladze, T.G. 登録日 2016-03-08 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 The Taf14 YEATS domain is a reader of histone crotonylation. Nat.Chem.Biol., 12, 2016
5VFP	Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome 分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ... 著者 Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. 登録日 2017-04-09 公開日 2018-07-18 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
1SHW	EphB2 / EphrinA5 Complex Structure 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, Ephrin-A5, ... 著者 Himanen, J.P, Chumley, M.J, Lackmann, M, Li, C, Barton, W.A, Jeffrey, P.D, Vearing, C, Geleick, D, Feldheim, D.A, Boyd, A.W. 登録日 2004-02-26 公開日 2004-05-18 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling Nat.Neurosci., 7, 2004
5IOO	Accommodation of massive sequence variation in Nanoarchaeota by the C-type lectin fold 分子名称: AvpA, MAGNESIUM ION 著者 Handa, S, Paul, B, Miller, J, Valentine, D, Ghosh, P. 登録日 2016-03-08 公開日 2016-11-09 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.521 Å) 主引用文献 Conservation of the C-type lectin fold for accommodating massive sequence variation in archaeal diversity-generating retroelements. Bmc Struct.Biol., 16, 2016
7LP8	The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476 分子名称: (phenylmethyl) (2~{S})-2-[5-oxidanyl-6-oxidanylidene-4-(2-pyridin-4-ylethylcarbamoyl)-1~{H}-pyrimidin-2-yl]pyrrolidine-1-carboxylate, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Slavish, P.J, Rankovic, Z, White, S.W. 登録日 2021-02-11 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000983476 To Be Published
5VNU	Nonheme Iron Replacement in a Biosynthetic Nitric Oxide Reductase Model Performing O2 Reduction to Water: Mn-bound FeBMb 分子名称: MANGANESE (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE 著者 Reed, J, Shi, Y, Zhu, Q, Chakraborty, S, Mirs, E.N, Petrik, I.D, Bhagi-Damodaran, A, Ross, M, Moenne-Loccoz, P, Zhang, Y, Lu, Y. 登録日 2017-05-01 公開日 2017-08-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.584 Å) 主引用文献 Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism. J. Am. Chem. Soc., 139, 2017
5IOV	Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine/Ro25-6981-bound conformation 分子名称: 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, GLUTAMIC ACID, GLYCINE, ... 著者 Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E. 登録日 2016-03-09 公開日 2016-04-20 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (7.5 Å) 主引用文献 Mechanism of NMDA Receptor Inhibition and Activation. Cell, 165, 2016
7LPY	Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases 分子名称: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ... 著者 Thapar, R, Andrew, A.S, Tainer, J.A. 登録日 2021-02-12 公開日 2022-02-16 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases To Be Published
5VNY	Crystal structure of DM14-3 domain of Lgd 分子名称: Lethal (2) giant discs 1, isoform B 著者 McMillan, B.J, Blacklow, S.C. 登録日 2017-05-01 公開日 2017-06-14 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.101 Å) 主引用文献 Structural Basis for Regulation of ESCRT-III Complexes by Lgd. Cell Rep, 19, 2017
7M24	Human carbonic anhydrase II in complex with (R)-rosiglitazone 分子名称: (R)-ROSIGLITAZONE, Carbonic anhydrase 2, ZINC ION 著者 Mueller, S.L, Peat, T.S. 登録日 2021-03-16 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors-A Spin-Off Discovery from Fragment Screening. Molecules, 26, 2021
5IPV	Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 1 分子名称: Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a 著者 Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, McHaourab, S.H, Gouaux, E. 登録日 2016-03-10 公開日 2016-04-20 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (9.25 Å) 主引用文献 Mechanism of NMDA Receptor Inhibition and Activation. Cell, 165, 2016
5IQA	Aminoglycoside Phosphotransferase (2'')-Ia (CTD of AAC(6')-Ie/APH(2'')-Ia) in complex with GMPPNP and Magnesium 分子名称: Bifunctional AAC/APH, CHLORIDE ION, MAGNESIUM ION, ... 著者 Caldwell, S.J, Berghuis, A.M. 登録日 2016-03-10 公開日 2016-05-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2)-Ia. Structure, 24, 2016
7LPZ	Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3-prime - 5-prime exoribonucleases 分子名称: ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 3, GLYCEROL, ... 著者 Thapar, R, Andrew, A.S, Tainer, J.A. 登録日 2021-02-12 公開日 2022-02-16 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structures and ribonuclease activity of the Flavivirus host factor ERI3 that is involved in viral RNA synthesis define the ERI subfamily of structure-specific 3' - 5' exoribonucleases To Be Published
5VX2	Mcl-1 in complex with Bim-h3Pc-RT 分子名称: 1,2-ETHANEDIOL, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog,Induced myeloid leukemia cell differentiation protein Mcl-1 chimera 著者 Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E. 登録日 2017-05-23 公開日 2017-11-15 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
5IQO	Crystal structure of the E. coli type 1 pilus subunit FimG (engineered variant with substitutions Q134E and S138E; N-terminal FimG residues 1-12 truncated) in complex with the donor strand peptide DsF_T4R-T6R-D13N 分子名称: 1,2-ETHANEDIOL, COBALT (II) ION, PENTAETHYLENE GLYCOL, ... 著者 Giese, C, Eras, J, Kern, A, Capitani, G, Glockshuber, R. 登録日 2016-03-11 公開日 2016-07-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.302 Å) 主引用文献 Accelerating the Association of the Most Stable Protein-Ligand Complex by More than Two Orders of Magnitude. Angew.Chem.Int.Ed.Engl., 55, 2016
5VIF	Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase 分子名称: 2-{[(2E)-4-chlorobut-2-enoyl]amino}-2-deoxy-beta-D-glucopyranose, CKII, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ... 著者 Jiang, J, Li, B, Hu, C.-W, Worth, M, Fan, D, Li, H. 登録日 2017-04-15 公開日 2017-10-18 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase. Nat. Chem. Biol., 13, 2017
5IR3	Crystal structure of the recombinant highest fibrillogenic natural mutant (obtained from patient AR) derived from lambda 6 light chain variable domain 分子名称: ACETATE ION, Ig lambda chain V-VI region AR 著者 Hernandez-Santoyo, A, Rodriguez-Romero, A. 登録日 2016-03-11 公開日 2017-06-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Stabilizing an amyloidogenic lambda 6 light chain variable domain. FEBS J., 284, 2017
7LI1	Crystal structure of holo Moraxella catarrhalis ferric binding protein A in an open conformation 分子名称: CARBONATE ION, FE (III) ION, Fe(3+) ABC transporter substrate-binding protein 著者 Chan, C, Ng, D, Fraser, M.E, Schryvers, A.B. 登録日 2021-01-26 公開日 2022-02-23 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and functional insights into iron acquisition from lactoferrin and transferrin in Gram-negative bacterial pathogens. Biometals, 2022
7LRR	Co-bound crystal structure of the engineered cyt cb562 variant, DiCyt2, crystallized in the presence of Cu(II) (M1) and Co(II) (M2) 分子名称: COBALT (II) ION, HEME C, Soluble cytochrome b562 著者 Choi, T.S, Tezcan, F.A. 登録日 2021-02-17 公開日 2022-02-23 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Overcoming universal restrictions on metal selectivity by protein design. Nature, 603, 2022
5IMJ	Crystal structure of a Z-ring associated protein from Escherichia coli 分子名称: Cell division protein ZapD, SULFATE ION 著者 Choi, H, Yoon, H.J, Lee, H.H. 登録日 2016-03-06 公開日 2017-03-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of ZapD, a positive regulator of Z-ring formation during bacterial cytokinesis To Be Published
5IMQ	Structure of ribosome bound to cofactor at 3.8 angstrom resolution 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Kumar, V, Ero, R, Jian, G.K, Ahmed, T, Zhan, Y, Bhushan, S, Gao, Y.G. 登録日 2016-03-06 公開日 2016-05-18 最終更新日 2025-09-17 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome J.Biol.Chem., 291, 2016
7LSL	Cu-bound crystal structure of the engineered cyt cb562 variant, DiCyt2 - H63A, crystallized in the presence of Ni(II) 分子名称: HEME C, NICKEL (II) ION, Soluble cytochrome b562 著者 Choi, T.S, Tezcan, F.A. 登録日 2021-02-18 公開日 2022-02-23 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structure-guided metal selectivity in malleable protein interface mediated by single disulfide bond To Be Published
5IRO	Crystal structure of a complex between the Human adenovirus type 4 E3-19K protein and MHC class molecule HLA-A2/TAX 分子名称: Beta-2-microglobulin, E3 19 kDa protein, HLA class I histocompatibility antigen, ... 著者 Li, L, Bouvier, M. 登録日 2016-03-14 公開日 2016-08-24 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Structure of the Adenovirus Type 4 (Species E) E3-19K/HLA-A2 Complex Reveals Species-Specific Features in MHC Class I Recognition. J Immunol., 197, 2016

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