PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

---

3TM2	Crystal structure of mature ThnT with a covalently bound product mimic 分子名称: (2R)-N-(4-chloro-3-oxobutyl)-2,4-dihydroxy-3,3-dimethylbutanamide, cysteine transferase 著者 Schildbach, J.F, Wright, N.T, Buller, A.R. 登録日 2011-08-30 公開日 2012-07-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Autoproteolytic Activation of ThnT Results in Structural Reorganization Necessary for Substrate Binding and Catalysis. J.Mol.Biol., 422, 2012
1HI3	Eosinophil-derived Neurotoxin (EDN) - Adenosine 2'-5'-Diphosphate Complex 分子名称: ADENOSINE-2'-5'-DIPHOSPHATE, EOSINOPHIL-DERIVED NEUROTOXIN 著者 Leonidas, D.D, Boix, E, Prill, R, Suzuki, M, Turton, R, Minson, K, Swaminathan, G.J, Youle, R.J, Acharya, K.R. 登録日 2001-01-02 公開日 2001-05-31 最終更新日 2018-05-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors J.Biol.Chem., 276, 2001
2VAI	Solution structure of a B-DNA hairpin at high pressure 分子名称: 5'-D(*AP*GP*GP*AP*TP*CP*CP*TP*UP*TP *TP*GP*GP*AP*TP*CP*CP*T)-3' 著者 Williamson, M.P, Wilton, D.J, Ghosh, M, Chary, K.V.A, Akasaka, K. 登録日 2007-08-31 公開日 2007-09-11 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural change in a B-DNA helix with hydrostatic pressure. Nucleic Acids Res., 36, 2008
4OB9	Crystal structure of chorismate synthase from Acinetobacter baumannii at 2.50A resolution 分子名称: Chorismate synthase 著者 Shukla, P.K, Chaudhary, A, Singh, N, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. 登録日 2014-01-07 公開日 2014-01-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of chorismate synthase from Acinetobacter baumannii at 2.50A resolution To be Published
4CT3	Methylmercury chloride derivative structure of the lytic CHAPK domain of the endolysin LysK from Staphylococcus aureus bacteriophage K 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Sanz-Gaitero, M, Keary, R, Garcia-Doval, C, Coffey, A, van Raaij, M.J. 登録日 2014-03-12 公開日 2014-08-06 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Crystal structure of the lytic CHAP(K) domain of the endolysin LysK from Staphylococcus aureus bacteriophage K. Virol. J., 11, 2014
2W5G	RNASE A-5'-ATP COMPLEX 分子名称: ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEASE PANCREATIC 著者 Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R. 登録日 2008-12-10 公開日 2009-02-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Influence of Naturally-Occurring 5'-Pyrophosphate- Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study. Biopolymers, 91, 2009
1MF5	GCATGCT Quadruplex 分子名称: 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', COBALT HEXAMMINE(III) 著者 Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Cardin, C.J. 登録日 2002-08-09 公開日 2003-02-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Crystal structure of the complementary quadruplex formed by d(GCATGCT) at atomic resolution Nucleic Acids Res., 31, 2003
2WD2	A chimeric microtubule disruptor with efficacy on a taxane resistant cell line 分子名称: 7-methoxy-2-(3-methoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-6-yl sulfamate, CARBONIC ANHYDRASE 2, FORMIC ACID, ... 著者 Leese, M.P, Jourdan, F.L, Kimberley, M.R, Cozier, G.E, Regis-Lydi, S, Foster, P.A, Newman, S.P, Thiyagarajan, N, Acharya, K.R, Ferrandis, E, Purohit, A, Reed, M.J, Potter, B.V.L. 登録日 2009-03-19 公開日 2010-03-31 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Chimeric Microtubule Disruptors. Chem.Commun.(Camb.), 46, 2010
4O44	Crystal Structure of HIV-1 Reverse Transcriptase in complex with 4-((4-(mesitylamino)-6-(3-morpholinopropoxy)-1,3,5-triazin-2-yl)amino)benzonitrile (JLJ529), a non-nucleoside inhibitor 分子名称: 4-({4-[3-(morpholin-4-yl)propoxy]-6-[(2,4,6-trimethylphenyl)amino]-1,3,5-triazin-2-yl}amino)benzonitrile, HIV-1 reverse transcriptase, p51 subunit, ... 著者 Mislak, A.C, Frey, K.M, Anderson, K.S. 登録日 2013-12-18 公開日 2014-05-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.889 Å) 主引用文献 A mechanistic and structural investigation of modified derivatives of the diaryltriazine class of NNRTIs targeting HIV-1 reverse transcriptase. Biochim.Biophys.Acta, 1840, 2014
2X1N	Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design 分子名称: 2-METHYL-N-[(1Z)-3-NITROCYCLOHEXA-2,4-DIEN-1-YLIDENE]-4,5-DIHYDRO[1,3]THIAZOLO[4,5-H]QUINAZOLIN-8-AMINE, ACE-LEU-ASN-PFF-NH2, CELL DIVISION PROTEIN KINASE 2, ... 著者 Kontopidis, G, Andrews, M.J, McInnes, C, Plater, A, Innes, L, Renachowski, S, Cowan, A, Fischer, P.M, McIntyre, N.A, Griffiths, G, Barnett, A.L, Slawin, A.M.Z, Jackson, W, Thomas, M, Zheleva, D.I, Wang, S, Blake, D.G, Westwood, N.J. 登録日 2009-12-31 公開日 2010-02-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Design, Synthesis, and Evaluation of 2-Methyl- and 2-Amino-N-Aryl-4,5-Dihydrothiazolo[4,5-H]Quinazolin-8-Amines as Ring-Constrained 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Cyclin-Dependent Kinase Inhibitors. J.Med.Chem., 53, 2010
3UVF	Expanding LAGALIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Intron-encoded DNA endonuclease I-HjeMI, ... 著者 Jacoby, K, Metzger, M, Shen, B, Jarjour, J, Stoddard, B, Scharenberg, A. 登録日 2011-11-29 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space. Nucleic Acids Res., 40, 2012
3ZPQ	Thermostabilised turkey beta1 adrenergic receptor with 4-(piperazin-1- yl)-1H-indole bound (compound 19) 分子名称: 4-(PIPERAZIN-1-YL)-1H-INDOLE, BETA-1 ADRENERGIC RECEPTOR, CHOLESTEROL HEMISUCCINATE, ... 著者 Christopher, J.A, Congreve, M, Dore, A.S, Marshall, F.H, Myszka, D.G, Brown, J, Koglin, M, Tehan, B, Errey, J.C, Tate, C.G, Warne, T. 登録日 2013-03-01 公開日 2013-04-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Biophysical Fragment Screening of the Beta1-Adrenergic Receptor: Identification of High Affinity Aryl Piperazine Leads Using Structure-Based Drug Design. J.Med.Chem., 56, 2013
3ZO2	The Synthesis and Evaluation of Diazaspirocyclic Protein Kinase Inhibitors 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 6-(2,9-Diazaspiro[5.5]undecan-9-yl)-9H-purine, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, ... 著者 Allen, C.E, Chow, C.L, Caldwell, J.J, Westwood, I.M, van Montfort, R.L, Collins, I. 登録日 2013-02-20 公開日 2013-03-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Synthesis and evaluation of heteroaryl substituted diazaspirocycles as scaffolds to probe the ATP-binding site of protein kinases. Bioorg. Med. Chem., 21, 2013
2WGZ	Crystal structure of alpha-1,3 galactosyltransferase (alpha3GT) in a complex with p-nitrophenyl-beta-galactoside (pNP-beta-Gal) 分子名称: 4-nitrophenyl beta-D-galactopyranoside, GLYCEROL, MANGANESE (II) ION, ... 著者 Jamaluddin, H, Tumbale, P, Ferns, T.A, Thiyagarajan, N, Brew, K, Acharya, K.R. 登録日 2009-04-28 公開日 2009-06-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Crystal Structure of Alpha-1,3 Galactosyltransferase (Alpha3Gt) in a Complex with P-Nitrophenyl-Beta-Galactoside (Pnpbetagal). Biochem.Biophys.Res.Commun., 385, 2009
2W5L	RNASE A-NADP COMPLEX 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RIBONUCLEASE PANCREATIC 著者 Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R. 登録日 2008-12-10 公開日 2009-02-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Influence of Naturally-Occurring 5'-Pyrophosphate-Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study. Biopolymers, 91, 2009
1K4V	1.53 A Crystal Structure of the Beta-Galactoside-alpha-1,3-galactosyltransferase in Complex with UDP 分子名称: GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... 著者 Boix, E, Swaminathan, G.J, Zhang, Y, Natesh, R, Brew, K, Acharya, K.R. 登録日 2001-10-09 公開日 2002-04-10 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Structure of UDP complex of UDP-galactose:beta-galactoside-alpha -1,3-galactosyltransferase at 1.53-A resolution reveals a conformational change in the catalytically important C terminus. J.Biol.Chem., 276, 2001
4MXV	Structure of Lymphotoxin alpha bound to anti-LTa Fab 分子名称: Lymphotoxin-alpha, anti-Lymphotoxin alpha antibody heavy chain, anti-Lymphotoxin alpha antibody light chain 著者 Yin, J.P, Hymowitz, S.G. 登録日 2013-09-26 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Dimerization of LT beta R by LT alpha 1 beta 2 is necessary and sufficient for signal transduction. Proc.Natl.Acad.Sci.USA, 110, 2013
1OUW	Crystal structure of Calystegia sepium agglutinin 分子名称: 1,2-ETHANEDIOL, D-MALATE, IMIDAZOLE, ... 著者 Bourne, Y, Roig-Zamboni, V, Barre, A, Peumans, W.J, Astoul, C.H, van Damme, E.J.M, Rouge, P. 登録日 2003-03-25 公開日 2003-11-11 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 The crystal structure of the Calystegia sepium agglutinin reveals a novel quaternary arrangement of lectin subunits with a beta-prism fold J.Biol.Chem., 279, 2004
3RP7	Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD and uric acid 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, URIC ACID, flavoprotein monooxygenase 著者 Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E. 登録日 2011-04-26 公開日 2012-05-16 最終更新日 2013-02-06 実験手法 X-RAY DIFFRACTION (2.042 Å) 主引用文献 Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae. Biochemistry, 52, 2013
4BEY	Night blindness causing G90D rhodopsin in complex with GaCT2 peptide 分子名称: ACETATE ION, Guanine nucleotide-binding protein G(t) subunit alpha-1, PALMITIC ACID, ... 著者 Singhal, A, Ostermaier, M.K, Vishnivetskiy, S.A, Panneels, V, Homan, K.T, Tesmer, J.J.G, Veprintsev, D, Deupi, X, Gurevich, V.V, Schertler, G.F.X, Standfuss, J. 登録日 2013-03-12 公開日 2013-05-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insights Into Congenital Stationary Night Blindness Based on the Structure of G90D Rhodopsin. Embo Rep., 14, 2013
2VZB	A Dodecameric Thioferritin in the Bacterial Domain, Characterization of the Bacterioferritin-Related Protein from Bacteroides fragilis 分子名称: BENZAMIDINE, FE (III) ION, MAGNESIUM ION, ... 著者 Gauss, G.H, Young, M.J, Douglas, T, Lawrence, C.M. 登録日 2008-07-31 公開日 2009-11-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Characterization of the Bacteroides Fragilis Bfr Gene Product Identifies a Bacterial Dps-Like Protein and Suggests Evolutionary Links in the Ferritin Superfamily. J.Bacteriol., 194, 2012
4BBM	CRYSTAL STRUCTURE OF THE HUMAN CDKL2 KINASE DOMAIN WITH BOUND TCS 2312 分子名称: 1,2-ETHANEDIOL, 4'-[5-[[3-[(CYCLOPROPYLAMINO)METHYL]PHENYL]AMINO]-1H-PYRAZOL-3-YL]-[1,1'-BIPHENYL]-2,4-DIOL, CHLORIDE ION, ... 著者 Canning, P, Elkins, J.M, Cooper, C.D.O, Mahajan, P, Daga, N, Berridge, G, Burgess-Brown, N, Muniz, J.R.C, Krojer, T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Bullock, A. 登録日 2012-09-26 公開日 2012-10-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function. Cell Rep, 22, 2018
4BGQ	Crystal structure of the human CDKL5 kinase domain 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CYCLIN-DEPENDENT KINASE-LIKE 5, ... 著者 Canning, P, Krojer, T, Goubin, S, Mahajan, P, Vollmar, M, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. 登録日 2013-03-28 公開日 2013-05-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function. Cell Rep, 22, 2018
2W5K	RNASE A-NADPH COMPLEX 分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RIBONUCLEASE PANCREATIC 著者 Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R. 登録日 2008-12-10 公開日 2009-02-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Influence of Naturally-Occurring 5'-Pyrophosphate-Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study. Biopolymers, 91, 2009
3X43	Crystal structure of O-ureido-L-serine synthase 分子名称: O-ureido-L-serine synthase, PYRIDOXAL-5'-PHOSPHATE 著者 Matoba, Y, Uda, N, Oda, K, Sugiyama, M. 登録日 2015-03-13 公開日 2015-07-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The structural and mutational analyses of O-ureido-L-serine synthase necessary for D-cycloserine biosynthesis. Febs J., 282, 2015

<243244245246247248249250251252253254255256257258>