4IAE
| Crystal structure of BAY 60-2770 bound to nostoc H-NOX domain | 分子名称: | 4-({(4-carboxybutyl)[2-(5-fluoro-2-{[4'-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]amino}methyl)benzoic acid, Alr2278 protein, MALONATE ION | 著者 | Kumar, V, van den Akker, F, Martin, F. | 登録日 | 2012-12-06 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Insights into BAY 60-2770 Activation and S-Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain Complexes. Biochemistry, 52, 2013
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4IAH
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4IAM
| Crystal Structure of the C139A mutant of nostoc H-NOX domain | 分子名称: | Alr2278 protein, MALONATE ION, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Kumar, V, van den Akker, F. | 登録日 | 2012-12-06 | 公開日 | 2013-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Insights into BAY 60-2770 Activation and S-Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain Complexes. Biochemistry, 52, 2013
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4DZM
| A de novo designed Coiled Coil CC-Di | 分子名称: | COILED-COIL PEPTIDE CC-DI | 著者 | Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. | 登録日 | 2012-03-01 | 公開日 | 2012-08-29 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
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6UD7
| Crystal structure of full-length human DCAF15-DDB1(deltaBPB)-DDA1-RBM39 in complex with indisulam | 分子名称: | DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1,DNA damage-binding protein 1, ... | 著者 | Bussiere, D.E, Shu, W, Xie, L, Knapp, M. | 登録日 | 2019-09-18 | 公開日 | 2019-12-18 | 最終更新日 | 2020-01-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex. Nat.Chem.Biol., 16, 2020
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4DOM
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4DZL
| A de novo designed Coiled Coil CC-Tri | 分子名称: | COILED-COIL PEPTIDE CC-TRI | 著者 | Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. | 登録日 | 2012-03-01 | 公開日 | 2012-08-29 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
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6UE5
| Crystal structure of full-length human DCAF15-DDB1-deltaPBP-DDA1-RBM39 in complex with 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide | 分子名称: | 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ... | 著者 | Knapp, M.S, Shu, W, Xie, L, Bussiere, D.E. | 登録日 | 2019-09-20 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex. Nat.Chem.Biol., 16, 2020
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4G1H
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4K80
| Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 2:0 ceramide-1-phosphate (2:0-C1P) | 分子名称: | (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | 著者 | Simanshu, D.K, Brown, R.E, Patel, D.J. | 登録日 | 2013-04-17 | 公開日 | 2013-07-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.051 Å) | 主引用文献 | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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4DZN
| A de novo designed Coiled Coil CC-pIL | 分子名称: | COILED-COIL PEPTIDE CC-PIL | 著者 | Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. | 登録日 | 2012-03-01 | 公開日 | 2012-08-29 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
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4DZK
| A de novo designed Coiled Coil CC-Tri-N13 | 分子名称: | CHLORIDE ION, COILED-COIL PEPTIDE CC-TRI-N13 | 著者 | Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. | 登録日 | 2012-03-01 | 公開日 | 2012-08-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
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4K84
| Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 16:0 ceramide-1-phosphate (16:0-C1P) | 分子名称: | (2S,3R,4E)-2-(hexadecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | 著者 | Simanshu, D.K, Brown, R.E, Patel, D.J. | 登録日 | 2013-04-17 | 公開日 | 2013-07-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | 主引用文献 | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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4G1J
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4KBR
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4KBS
| Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 12:0 phosphatidic acid (12:0 PA) | 分子名称: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-ETHANEDIOL, Glycolipid transfer protein domain-containing protein 1 | 著者 | Simanshu, D.K, Brown, R.E, Patel, D.J. | 登録日 | 2013-04-23 | 公開日 | 2013-07-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | 主引用文献 | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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4KIO
| Kinase domain mutant of human Itk in complex with a covalently-binding inhibitor | 分子名称: | 1-[(3S)-3-{[4-(morpholin-4-ylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)pyrimidin-2-yl]amino}pyrrolidin-1-yl]prop-2-en-1-one, 1-[(3S)-3-{[4-(morpholin-4-ylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)pyrimidin-2-yl]amino}pyrrolidin-1-yl]propan-1-one, GLYCEROL, ... | 著者 | Somers, D.O. | 登録日 | 2013-05-02 | 公開日 | 2013-08-21 | 最終更新日 | 2014-02-12 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Discovery of novel irreversible inhibitors of interleukin (IL)-2-inducible tyrosine kinase (Itk) by targeting cysteine 442 in the ATP pocket. J.Biol.Chem., 288, 2013
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4KF6
| Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 8:0 Ceramide-1-Phosphate (8:0-C1P) | 分子名称: | (2S,3R,4E)-3-hydroxy-2-(octanoylamino)octadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | 著者 | Simanshu, D.K, Brown, R.E, Patel, D.J. | 登録日 | 2013-04-26 | 公開日 | 2013-07-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.195 Å) | 主引用文献 | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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4K85
| Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 12:0 Ceramide-1-Phosphate (12:0-C1P) | 分子名称: | (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | 著者 | Simanshu, D.K, Brown, R.E, Patel, D.J. | 登録日 | 2013-04-17 | 公開日 | 2013-07-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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4K8N
| Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 18:1 Ceramide-1-Phosphate (18:1-C1P) | 分子名称: | (2S,3R,4Z)-3-hydroxy-2-[(9E)-octadec-9-enoylamino]octadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | 著者 | Simanshu, D.K, Brown, R.E, Patel, D.J. | 登録日 | 2013-04-18 | 公開日 | 2013-07-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.102 Å) | 主引用文献 | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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4EO7
| Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88. | 分子名称: | MAGNESIUM ION, Myeloid differentiation primary response protein MyD88 | 著者 | Snyder, G.A, Cirl, C, Jiang, J.S, Chen, P, Smith, T, Xiao, T.S. | 登録日 | 2012-04-13 | 公開日 | 2013-04-10 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.449 Å) | 主引用文献 | Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli. Proc.Natl.Acad.Sci.USA, 110, 2013
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4JLG
| SETD7 in complex with inhibitor (R)-PFI-2 and S-adenosyl-methionine | 分子名称: | 8-fluoro-N-{(2R)-1-oxo-1-(pyrrolidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-2-yl}-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide, Histone-lysine N-methyltransferase SETD7, S-ADENOSYLMETHIONINE, ... | 著者 | Dong, A, Wu, H, Zeng, H, El Bakkouri, M, Barsyte, D, Vedadi, M, Tatlock, J, Owen, D, Bunnage, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2013-03-12 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.896 Å) | 主引用文献 | (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells. Proc.Natl.Acad.Sci.USA, 111, 2014
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6VJB
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6W5D
| Crystal Structure of Fab RSB1 | 分子名称: | RSB1 Fab Heavy Chain, RSB1 Fab Light Chain | 著者 | Harshbarger, W, Chandramouli, S, Malito, M. | 登録日 | 2020-03-13 | 公開日 | 2020-11-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F. Plos Pathog., 16, 2020
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6P9S
| E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 7 | 分子名称: | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... | 著者 | Ma, X, Shia, S, Ornelas, E. | 登録日 | 2019-06-10 | 公開日 | 2020-03-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
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