4KF6
Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 8:0 Ceramide-1-Phosphate (8:0-C1P)
Summary for 4KF6
Entry DOI | 10.2210/pdb4kf6/pdb |
Related | 4K80 4K84 4K85 4K8N 4KBR 4KBS |
Descriptor | Glycolipid transfer protein domain-containing protein 1, (2S,3R,4E)-3-hydroxy-2-(octanoylamino)octadec-4-en-1-yl dihydrogen phosphate (3 entities in total) |
Functional Keywords | lipid transfer protein, gltp-fold, cptp, c1p, ceramide-1-phosphate, protein-lipid complex, eicosanoid, lipid transport |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 149938.93 |
Authors | Simanshu, D.K.,Brown, R.E.,Patel, D.J. (deposition date: 2013-04-26, release date: 2013-07-17, Last modification date: 2023-11-29) |
Primary citation | Simanshu, D.K.,Kamlekar, R.K.,Wijesinghe, D.S.,Zou, X.,Zhai, X.,Mishra, S.K.,Molotkovsky, J.G.,Malinina, L.,Hinchcliffe, E.H.,Chalfant, C.E.,Brown, R.E.,Patel, D.J. Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500:463-467, 2013 Cited by PubMed: 23863933DOI: 10.1038/nature12332 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.195 Å) |
Structure validation
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