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4KF6

Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 8:0 Ceramide-1-Phosphate (8:0-C1P)

Summary for 4KF6
Entry DOI10.2210/pdb4kf6/pdb
Related4K80 4K84 4K85 4K8N 4KBR 4KBS
DescriptorGlycolipid transfer protein domain-containing protein 1, (2S,3R,4E)-3-hydroxy-2-(octanoylamino)octadec-4-en-1-yl dihydrogen phosphate (3 entities in total)
Functional Keywordslipid transfer protein, gltp-fold, cptp, c1p, ceramide-1-phosphate, protein-lipid complex, eicosanoid, lipid transport
Biological sourceHomo sapiens (human)
Total number of polymer chains6
Total formula weight149938.93
Authors
Simanshu, D.K.,Brown, R.E.,Patel, D.J. (deposition date: 2013-04-26, release date: 2013-07-17, Last modification date: 2023-11-29)
Primary citationSimanshu, D.K.,Kamlekar, R.K.,Wijesinghe, D.S.,Zou, X.,Zhai, X.,Mishra, S.K.,Molotkovsky, J.G.,Malinina, L.,Hinchcliffe, E.H.,Chalfant, C.E.,Brown, R.E.,Patel, D.J.
Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500:463-467, 2013
Cited by
PubMed: 23863933
DOI: 10.1038/nature12332
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.195 Å)
Structure validation

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