6VJB

Crystal structure of a catalytically inactive CXC Chemokine-degrading protease SpyCEP from Streptococcus pyogenes

Summary for 6VJB

• Entry DOI: 10.2210/pdb6vjb/pdb
• Descriptor: Putative cell envelope proteinase, 1,2-ETHANEDIOL, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: vaccine, serine-protease, group a streptococcus, immune system
• Biological source: Streptococcus pyogenes
• Total number of polymer chains: 1
• Total formula weight: 175602.04

Authors

Malito, E.,Rouse, S. (deposition date: 2020-01-15, release date: 2020-04-15, Last modification date: 2023-10-11)

• Primary citation: McKenna, S.,Malito, E.,Rouse, S.L.,Abate, F.,Bensi, G.,Chiarot, E.,Micoli, F.,Mancini, F.,Gomes Moriel, D.,Grandi, G.,Mossakowska, D.,Pearson, M.,Xu, Y.,Pease, J.,Sriskandan, S.,Margarit, I.,Bottomley, M.J.,Matthews, S.; Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes.; Comput Struct Biotechnol J, 18:650-660, 2020; PubMed: 32257048; DOI: 10.1016/j.csbj.2020.03.004

Experimental method

X-RAY DIFFRACTION (2.24 Å)