6VJB

Crystal structure of a catalytically inactive CXC Chemokine-degrading protease SpyCEP from Streptococcus pyogenes

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Putative cell envelope proteinase	polymer	1589	175233.5	1	UniProt (Q9A180) Pfam (PF00082) Pfam (PF02225) Pfam (PF06280) In PDB	Streptococcus pyogenes
2	A	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
3	A	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
4		water	water		18.0	691	Chemie (HOH)

Sequence modifications

A: 34 - 1614 (UniProt: Q9A180)

PDB	External Database	Details
Met 33	-	initiating methionine
Ala 151	Asp 151	engineered mutation
Ala 617	Ser 617	engineered mutation
Glu 1615	-	expression tag
His 1616	-	expression tag
His 1617	-	expression tag
His 1618	-	expression tag
His 1619	-	expression tag
His 1620	-	expression tag
His 1621	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	175233.5
Non-Polymers*	Number of molecules	7
	Total formula weight	368.5
All*	Total formula weight	175602.0

*Water molecules are not included.