6CNK
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![BU of 6cnk by Molmil](/molmil-images/mine/6cnk) | Structure of the 3alpha2beta stiochiometry of the human Alpha4Beta2 nicotinic receptor | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Walsh Jr, R.M, Roh, S.H, Gharpure, A, Morales-Perez, C.L, Hibbs, R.E. | 登録日 | 2018-03-08 | 公開日 | 2018-05-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor. Nature, 557, 2018
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6CNJ
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![BU of 6cnj by Molmil](/molmil-images/mine/6cnj) | Structure of the 2alpha3beta stiochiometry of the human Alpha4Beta2 nicotinic receptor | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Walsh Jr, R.M, Roh, S.H, Gharpure, A, Morales-Perez, C.L, Teng, J, Hibbs, R.E. | 登録日 | 2018-03-08 | 公開日 | 2018-05-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor. Nature, 557, 2018
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3BT2
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![BU of 3bt2 by Molmil](/molmil-images/mine/3bt2) | Structure of urokinase receptor, urokinase and vitronectin complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, ... | 著者 | Huang, M. | 登録日 | 2007-12-27 | 公開日 | 2008-03-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes Nat.Struct.Mol.Biol., 15, 2008
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4M1D
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1DZB
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![BU of 1dzb by Molmil](/molmil-images/mine/1dzb) | Crystal structure of phage library-derived single-chain Fv fragment 1F9 in complex with turkey egg-white lysozyme | 分子名称: | SCFV FRAGMENT 1F9, TURKEY EGG-WHITE LYSOZYME C | 著者 | Ay, J, Keitel, T, Kuettner, G, Wessner, H, Scholz, C, Hahn, M, Hoehne, W. | 登録日 | 2000-02-23 | 公開日 | 2000-11-02 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of a Phage Library-Derived Single-Chain Fv Fragment Complexed with Turkey Egg -White Lysozyme at 2.0 A Resolution J.Mol.Biol., 301, 2000
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8W0Q
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5LHN
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![BU of 5lhn by Molmil](/molmil-images/mine/5lhn) | The catalytic domain of murine urokinase-type plasminogen activator in complex with the allosteric inhibitory nanobody Nb7 | 分子名称: | 1,2-ETHANEDIOL, Camelid-Derived Antibody Fragment Nb7, SULFATE ION, ... | 著者 | Kromann-Hansen, T, Lange, E.L, Sorensen, H.P, Ghassabeh, G.H, Huang, M, Jensen, J.K, Muyldermans, S, Declerck, P, Andreasen, P.A. | 登録日 | 2016-07-12 | 公開日 | 2017-06-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator. Sci Rep, 7, 2017
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5LHQ
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![BU of 5lhq by Molmil](/molmil-images/mine/5lhq) | The EGR-cmk active site inhibited catalytic domain of murine urokinase-type plasminogen activator in complex with the allosteric inhibitory nanobody Nb7 | 分子名称: | 1,2-ETHANEDIOL, Camelid-Derived Antibody Fragment Nb7, L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide, ... | 著者 | Kromann-Hansen, T, Lange, E.L, Sorensen, H.P, Ghassabeh, G.H, Huang, M, Jensen, J.K, Muyldermans, S, Declerck, P.J, Andreasen, P.A. | 登録日 | 2016-07-12 | 公開日 | 2017-06-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator. Sci Rep, 7, 2017
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6H2Y
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![BU of 6h2y by Molmil](/molmil-images/mine/6h2y) | human Fab 1E6 bound to fHbp variant 3 from Neisseria meningitidis serogroup B | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | Veggi, D, Bianchi, F, Cozzi, R, Malito, E, Bottomley, M.J. | 登録日 | 2018-07-17 | 公開日 | 2019-08-14 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6. Faseb J., 33, 2019
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3BGF
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6Y9B
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3DNO
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![BU of 3dno by Molmil](/molmil-images/mine/3dno) | Molecular structure for the HIV-1 gp120 trimer in the CD4-bound state | 分子名称: | HIV-1 envelope glycoprotein gp120 | 著者 | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | 登録日 | 2008-07-02 | 公開日 | 2008-08-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Molecular architecture of native HIV-1 gp120 trimers. Nature, 455, 2008
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3DNN
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![BU of 3dnn by Molmil](/molmil-images/mine/3dnn) | Molecular structure for the HIV-1 gp120 trimer in the unliganded state | 分子名称: | HIV-1 envelope glycoprotein gp120 | 著者 | Borgnia, M.J, Liu, J, Bartesaghi, A, Sapiro, G, Subramaniam, S. | 登録日 | 2008-07-02 | 公開日 | 2008-08-19 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Molecular architecture of native HIV-1 gp120 trimers. Nature, 455, 2008
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1XGY
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![BU of 1xgy by Molmil](/molmil-images/mine/1xgy) | Crystal Structure of Anti-Meta I Rhodopsin Fab Fragment K42-41L | 分子名称: | K42-41L Fab Heavy Chain, K42-41L Fab Light Chain, Rhodopsin Epitope Mimetic Peptide | 著者 | Piscitelli, C.L, Angel, T.E, Bailey, B.W, Lawerence, C.M. | 登録日 | 2004-09-17 | 公開日 | 2005-09-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Equilibrium between metarhodopsin-I and metarhodopsin-II is dependent on the conformation of the third cytoplasmic loop. J.Biol.Chem., 281, 2006
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8WDT
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![BU of 8wdt by Molmil](/molmil-images/mine/8wdt) | Crystal structure of the human adenosine A2A receptor in complex with photoresponsive ligand photoNECA(blue) | 分子名称: | (2S,3S,4R,5R)-5-(6-amino-2-((E)-phenyldiazenyl)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxytetrahydrofuran-2-carboxamide, Adenosine receptor A2a, Antibody Fab fragment heavy chain, ... | 著者 | Araya, T, Asada, H, Iwata, S, Im, D.H. | 登録日 | 2023-09-16 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Crystal structure reveals the binding mode and selectivity of a photoswitchable ligand for the adenosine A 2A receptor. Biochem.Biophys.Res.Commun., 695, 2023
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6W3H
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![BU of 6w3h by Molmil](/molmil-images/mine/6w3h) | Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATV Fc, Transferrin receptor protein 1,Transferrin receptor protein 1 | 著者 | Srivastava, A, Kariolis, M, Wells, R. | 登録日 | 2020-03-09 | 公開日 | 2020-06-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | 主引用文献 | Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys. Sci Transl Med, 12, 2020
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6VUP
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6VUN
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6VUO
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5WUV
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![BU of 5wuv by Molmil](/molmil-images/mine/5wuv) | Crystal structure of Certolizumab Fab | 分子名称: | heavy chain, light chain | 著者 | Heo, Y.S, Lee, J.U, Son, J.Y, Shin, W, Yoo, K.Y. | 登録日 | 2016-12-21 | 公開日 | 2017-06-07 | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | 主引用文献 | Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases Int J Mol Sci, 18, 2017
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2JB5
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![BU of 2jb5 by Molmil](/molmil-images/mine/2jb5) | Fab fragment in complex with small molecule hapten, crystal form-1 | 分子名称: | 2-{(1E,3Z,5E,7E)-7-[3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-1,3-DIHYDRO-2H-INDOL-2-YLIDENE]-4-METHYLHEPTA-1,3,5-TRIEN-1-YL}-3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-3H-INDOLIUM, FAB FRAGMENT MOR03268 HEAVY CHAIN, FAB FRAGMENT MOR03268 LIGHT CHAIN | 著者 | Hillig, R.C, Baesler, S, Malawski, G, Badock, V, Bahr, I, Schirner, M, Licha, K. | 登録日 | 2006-12-03 | 公開日 | 2008-01-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Fab Mor03268 Triggers Absorption Shift of a Diagnostic Dye Via Packaging in a Solvent-Shielded Fab Dimer Interface J.Mol.Biol., 377, 2008
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2JB6
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![BU of 2jb6 by Molmil](/molmil-images/mine/2jb6) | Fab fragment in complex with small molecule hapten, crystal form-2 | 分子名称: | 2-{(1E,3Z,5E,7E)-7-[3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-1,3-DIHYDRO-2H-INDOL-2-YLIDENE]-4-METHYLHEPTA-1,3,5-TRIEN-1-YL}-3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-3H-INDOLIUM, FAB FRAGMENT MOR03268 HEAVY CHAIN, FAB FRAGMENT MOR03268 LIGHT CHAIN | 著者 | Hillig, R.C, Baesler, S, Malawski, G, Badock, V, Bahr, I, Schirner, M, Licha, K. | 登録日 | 2006-12-03 | 公開日 | 2008-01-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Fab Mor03268 Triggers Absorption Shift of a Diagnostic Dye Via Packaging in a Solvent-Shielded Fab Dimer Interface J.Mol.Biol., 377, 2008
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6FRJ
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![BU of 6frj by Molmil](/molmil-images/mine/6frj) | Crystal structure of scFv-SM3 in complex with APD-SeThrGalNAc-RP | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, APD-SeThr-RP, ... | 著者 | Companon, I, Castro-Lopez, J, Escudero-Casao, M, Avenoza, A, Busto, J.H, Castillon, S, Jimenez-Barbero, J, Bernardes, G.J, Boutureira, O, Jimenez-Oses, G, Asensio, J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F. | 登録日 | 2018-02-16 | 公開日 | 2019-02-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage. J. Am. Chem. Soc., 141, 2019
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5WUX
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![BU of 5wux by Molmil](/molmil-images/mine/5wux) | TNFalpha-certolizumab Fab | 分子名称: | Tumor necrosis factor alpha, heavy, light | 著者 | Heo, Y.S, Lee, J.U. | 登録日 | 2016-12-21 | 公開日 | 2017-06-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Molecular Basis for the Neutralization of Tumor Necrosis Factor alpha by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases Int J Mol Sci, 18, 2017
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2I69
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![BU of 2i69 by Molmil](/molmil-images/mine/2i69) | Crystal structure of the West Nile virus envelope glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Polyprotein | 著者 | Kanai, R, Modis, Y. | 登録日 | 2006-08-28 | 公開日 | 2006-11-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Crystal structure of west nile virus envelope glycoprotein reveals viral surface epitopes. J.Virol., 80, 2006
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