2JB6

Fab fragment in complex with small molecule hapten, crystal form-2

Summary for 2JB6

Related2C0V 2JB5
DescriptorFAB FRAGMENT MOR03268 LIGHT CHAIN, FAB FRAGMENT MOR03268 HEAVY CHAIN, 2-{(1E,3Z,5E,7E)-7-[3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-1,3-DIHYDRO-2H-INDOL-2-YLIDENE]-4-METHYLHEPTA-1,3,5-TRIEN-1-YL}-3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-3H-INDOLIUM, ... (4 entities in total)
Functional Keywordscdr, tsc, fab, hucal, fluorescent dye, immunoglobulin domain, antibody fragment, diagnostic imaging, immune system
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains4
Total molecular weight99710.39
Authors
Hillig, R.C.,Baesler, S.,Malawski, G.,Badock, V.,Bahr, I.,Schirner, M.,Licha, K. (deposition date: 2006-12-03, release date: 2008-01-08, Last modification date: 2011-07-13)
Primary citation
Hillig, R.C.,Urlinger, S.,Fanghanel, J.,Brocks, B.,Haenel, C.,Stark, Y.,Sulzle, D.,Svergun, D.I.,Baesler, S.,Malawski, G.,Moosmayer, D.,Menrad, A.,Schirner, M.,Licha, K.
Fab Mor03268 Triggers Absorption Shift of a Diagnostic Dye Via Packaging in a Solvent-Shielded Fab Dimer Interface
J.Mol.Biol., 377:206-, 2008
PubMed: 18241888 (PDB entries with the same primary citation)
DOI: 10.1016/J.JMB.2007.12.071
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.85 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22690.7%11.7%4.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2jb6
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Molmil generated image of 2jb6
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Molmil generated image of 2jb6
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More Biological unit images

Molmil generated image of 2jb6
no rotation
Molmil generated image of 2jb6
rotated about x axis by 90°
Molmil generated image of 2jb6
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2jb6.pdb2.gz [130.59 KB])
Coordinate files for Biological unit (2jb6.pdb1.gz [131.26 KB])