2JB5

Fab fragment in complex with small molecule hapten, crystal form-1

Summary for 2JB5

• Entry DOI: 10.2210/pdb2jb5/pdb
• Related: 2C0V 2JB6
• Descriptor: FAB FRAGMENT MOR03268 HEAVY CHAIN, FAB FRAGMENT MOR03268 LIGHT CHAIN, 2-{(1E,3Z,5E,7E)-7-[3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-1,3-DIHYDRO-2H-INDOL-2-YLIDENE]-4-METHYLHEPTA-1,3,5-TRIEN-1-YL}-3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-3H-INDOLIUM, ... (4 entities in total)
• Functional Keywords: cdr, tsc, fab, hucal, fluorescent dye, immunoglobulin domain, antibody fragment, diagnostic imaging, immune system
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 49855.20

Authors

Hillig, R.C.,Baesler, S.,Malawski, G.,Badock, V.,Bahr, I.,Schirner, M.,Licha, K. (deposition date: 2006-12-03, release date: 2008-01-08, Last modification date: 2023-12-13)

• Primary citation: Hillig, R.C.,Urlinger, S.,Fanghanel, J.,Brocks, B.,Haenel, C.,Stark, Y.,Sulzle, D.,Svergun, D.I.,Baesler, S.,Malawski, G.,Moosmayer, D.,Menrad, A.,Schirner, M.,Licha, K.; Fab Mor03268 Triggers Absorption Shift of a Diagnostic Dye Via Packaging in a Solvent-Shielded Fab Dimer Interface; J.Mol.Biol., 377:206-, 2008; PubMed: 18241888; DOI: 10.1016/J.JMB.2007.12.071

Experimental method

X-RAY DIFFRACTION (2.8 Å)