2JB5

Fab fragment in complex with small molecule hapten, crystal form-1

Summary for 2JB5

Related2C0V 2JB6
DescriptorFAB FRAGMENT MOR03268 HEAVY CHAIN, FAB FRAGMENT MOR03268 LIGHT CHAIN, 2-{(1E,3Z,5E,7E)-7-[3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-1,3-DIHYDRO-2H-INDOL-2-YLIDENE]-4-METHYLHEPTA-1,3,5-TRIEN-1-YL}-3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-3H-INDOLIUM, ... (4 entities in total)
Functional Keywordscdr, tsc, fab, hucal, fluorescent dye, immunoglobulin domain, antibody fragment, diagnostic imaging, immune system
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total molecular weight49855.2
Authors
Hillig, R.C.,Baesler, S.,Malawski, G.,Badock, V.,Bahr, I.,Schirner, M.,Licha, K. (deposition date: 2006-12-03, release date: 2008-01-08, Last modification date: 2011-07-13)
Primary citation
Hillig, R.C.,Urlinger, S.,Fanghanel, J.,Brocks, B.,Haenel, C.,Stark, Y.,Sulzle, D.,Svergun, D.I.,Baesler, S.,Malawski, G.,Moosmayer, D.,Menrad, A.,Schirner, M.,Licha, K.
Fab Mor03268 Triggers Absorption Shift of a Diagnostic Dye Via Packaging in a Solvent-Shielded Fab Dimer Interface
J.Mol.Biol., 377:206-, 2008
PubMed: 18241888 (PDB entries with the same primary citation)
DOI: 10.1016/J.JMB.2007.12.071
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.202244.0%8.4%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2jb5
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Molmil generated image of 2jb5
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Molmil generated image of 2jb5
rotated about y axis by 90°