8WDT

Crystal structure of the human adenosine A2A receptor in complex with photoresponsive ligand photoNECA(blue)

Summary for 8WDT

• Entry DOI: 10.2210/pdb8wdt/pdb
• Descriptor: Adenosine receptor A2a, Antibody Fab fragment light chain, Antibody Fab fragment heavy chain, ... (4 entities in total)
• Functional Keywords: g-protein coupled receptor, gpcr, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 87197.35

Authors

Araya, T.,Asada, H.,Iwata, S.,Im, D.H. (deposition date: 2023-09-16, release date: 2024-01-17)

• Primary citation: Araya, T.,Matsuba, Y.,Suzuki, H.,Doura, T.,Nuemket, N.,Nango, E.,Yamamoto, M.,Im, D.,Asada, H.,Kiyonaka, S.,Iwata, S.; Crystal structure reveals the binding mode and selectivity of a photoswitchable ligand for the adenosine A 2A receptor.; Biochem.Biophys.Res.Commun., 695:149393-149393, 2023; PubMed: 38171234; DOI: 10.1016/j.bbrc.2023.149393

Experimental method

X-RAY DIFFRACTION (3.34 Å)