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7WIW
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BU of 7wiw by Molmil
Cryo-EM structure of Mycobacterium tuberculosis irtAB complexed with ATP in an occluded conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mycobactin import ATP-binding/permease protein IrtA, ...
著者Zhang, B, Sun, S, Yang, H, Rao, Z.
登録日2022-01-05
公開日2023-01-25
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB.
Protein Cell, 14, 2023
7U58
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BU of 7u58 by Molmil
YcaO-mediated ATP-dependent peptidase activity in ribosomal peptide biosynthesis
分子名称: MAGNESIUM ION, MusD, ZINC ION
著者Zheng, Y, Nair, S.K.
登録日2022-03-01
公開日2022-11-02
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献YcaO-mediated ATP-dependent peptidase activity in ribosomal peptide biosynthesis.
Nat.Chem.Biol., 19, 2023
1QQO
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BU of 1qqo by Molmil
E175S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, HYDROLASE (ACTING ON ACID ANHYDRIDES), ...
著者Johnson, E.R, McKay, D.B.
登録日1999-06-07
公開日1999-09-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mapping the role of active site residues for transducing an ATP-induced conformational change in the bovine 70-kDa heat shock cognate protein.
Biochemistry, 38, 1999
7THZ
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BU of 7thz by Molmil
Structure of Leucine Rich Repeat Kinase 2's ROC domain interacting with the microtubule facing the plus end
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2
著者Matyszewski, M, Leschziner, A.E.
登録日2022-01-12
公開日2022-12-28
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules.
Nat.Struct.Mol.Biol., 29, 2022
7THY
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BU of 7thy by Molmil
Structure of Leucine Rich Repeat Kinase 2's ROC domain interacting with the microtubule facing the minus end
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2
著者Matyszewski, M, Leschziner, A.E.
登録日2022-01-12
公開日2022-12-28
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules.
Nat.Struct.Mol.Biol., 29, 2022
1YLA
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BU of 1yla by Molmil
Ubiquitin-conjugating enzyme E2-25 kDa (Huntington interacting protein 2)
分子名称: Ubiquitin-conjugating enzyme E2-25 kDa
著者Choe, J, Avvakumov, G.V, Newman, E.M, Mackenzie, F, Kozieradzki, I, Bochkarev, A, Sundstrom, M, Arrowsmith, C, Edwards, A, Dhe-paganon, S, Structural Genomics Consortium (SGC)
登録日2005-01-19
公開日2005-02-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285, 2010
8BB8
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BU of 8bb8 by Molmil
Crystal structure of human aldehyde dehydrogenase ALDH3A1 in complex with octanal
分子名称: ACETATE ION, Aldehyde dehydrogenase, dimeric NADP-preferring, ...
著者Schwartz, M, Neiers, F.
登録日2022-10-12
公開日2023-04-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Characterization of human oxidoreductases involved in aldehyde odorant metabolism.
Sci Rep, 13, 2023
6EBG
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BU of 6ebg by Molmil
Ohr (Organic Hydroperoxide Resistance protein) mutant - C60S interacting with dihydrolipoamide
分子名称: (6S)-6,8-disulfanyloctanamide, Organic hydroperoxide resistance protein
著者Domingos, R.M, Teixeira, R.D, Alegria, T.G.P, Vieira, P.S, Murakami, M.T, Netto, L.E.S.
登録日2018-08-06
公開日2020-02-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Substrate and product-assisted catalysis: molecular aspects behind structural switches along Organic Hydroperoxide Resistance Protein catalytic cycle
Acs Catalysis, 2020
6WX5
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BU of 6wx5 by Molmil
Adducts formed after 3 weeks in the reaction of chlorido[chlorido(2,2'-((2-([2,2':6',2''-Terpyridin]-4'-yloxy)ethyl)azanediyl)bis(ethan-1-ol))platinum(II)] with HEWL
分子名称: ACETATE ION, Lysozyme, PLATINUM (II) ION, ...
著者Sullivan, M.P, Hartinger, C.G, Goldstone, D.C.
登録日2020-05-09
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Mustards-Derived Terpyridine-Platinum Complexes as Anticancer Agents: DNA Alkylation vs Coordination.
Inorg.Chem., 60, 2021
6EBD
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BU of 6ebd by Molmil
OhrB (Organic Hydroperoxide Resistance protein) mutant (C60A) from Chromobacterium violaceum, interacting with dihydrolipoamide
分子名称: (6S)-6,8-disulfanyloctanamide, CHLORIDE ION, Organic hydroperoxide resistance protein
著者Domingos, R.M, Teixeira, R.D, Alegria, T.G.P, Vieira, P.S, Murakami, M.T, Netto, L.E.S.
登録日2018-08-06
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Substrate and product-assisted catalysis: molecular aspects behind structural switches along Organic Hydroperoxide Resistance Protein catalytic cycle
Acs Catalysis, 2020
4BG2
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BU of 4bg2 by Molmil
X-ray Crystal Structure of PatF from Prochloron didemni
分子名称: PATF
著者Bent, A.F, Koehnke, J, Houssen, W.E, Smith, M.C.M, Jaspars, M, Naismith, J.H.
登録日2013-03-22
公開日2013-04-03
最終更新日2013-11-06
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structure of Patf from Prochloron Didemni.
Acta Crystallogr.,Sect.F, 69, 2013
2ZCY
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BU of 2zcy by Molmil
yeast 20S proteasome:syringolin A-complex
分子名称: (2S)-2-[[(2S)-1-[[(5S,8S,9E)-2,7-dioxo-5-propan-2-yl-1,6-diazacyclododeca-3,9-dien-8-yl]amino]-3-methyl-1-oxo-butan-2-yl]carbamoylamino]-3-methyl-butanoic acid, Proteasome component C1, Proteasome component C11, ...
著者Groll, M, Dudler, R, Kaiser, M.
登録日2007-11-15
公開日2008-04-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism
Nature, 452, 2008
8OFA
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BU of 8ofa by Molmil
Crystal structure of human cathepsin L interacting with tosyl phenylalanyl chloromethyl ketone (TPCK)
分子名称: 1,2-ETHANEDIOL, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 4-methyl-~{N}-[(2~{S})-4-oxidanyl-3-oxidanylidene-1-phenyl-butan-2-yl]benzenesulfonamide, ...
著者Falke, S, Lieske, J, Guenther, S, Ewert, W, Reinke, P.Y.A, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A.
登録日2023-03-14
公開日2023-11-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors.
J.Med.Chem., 67, 2024
8C0N
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BU of 8c0n by Molmil
Crystal structure of the red form of the mTagFT fluorescent timer
分子名称: Blue-to-red TagFT fluorescent timer
著者Boyko, K.M, Nikolaeva, A.Y, Vlaskina, A.V, Agapova, Y.K, Subach, O.M, Popov, V.O, Subach, F.V.
登録日2022-12-19
公開日2023-03-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Blue-to-Red TagFT, mTagFT, mTsFT, and Green-to-FarRed mNeptusFT2 Proteins, Genetically Encoded True and Tandem Fluorescent Timers.
Int J Mol Sci, 24, 2023
8CAI
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BU of 8cai by Molmil
Streptomycin and Hygromycin B bound to the 30S body
分子名称: 16S rRNA, 30S ribosomal protein S16, 30S ribosomal protein S2, ...
著者Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N.
登録日2023-01-24
公開日2023-07-26
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.08 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
6Y3P
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BU of 6y3p by Molmil
Crystal structure of the C-terminal domain from K. lactis Pby1, an ATP-grasp enzyme interacting with the mRNA decapping enzyme Dcp2
分子名称: KLLA0B12012p, SULFATE ION
著者Graille, M.
登録日2020-02-18
公開日2020-04-29
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Pby1 is a direct partner of the Dcp2 decapping enzyme.
Nucleic Acids Res., 48, 2020
7Q49
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BU of 7q49 by Molmil
Local refinement structure of the N-domain of full-length, monomeric, soluble somatic angiotensin I-converting enzyme
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ZINC ION, ...
著者Lubbe, L, Sewell, B.T, Sturrock, E.D.
登録日2021-10-29
公開日2022-07-20
最終更新日2022-08-24
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Cryo-EM reveals mechanisms of angiotensin I-converting enzyme allostery and dimerization.
Embo J., 41, 2022
6Y3Y
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BU of 6y3y by Molmil
Human Coronavirus HKU1 Haemagglutinin-Esterase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-esterase, ...
著者Hurdiss, D.L, Drulyte, I, Pronker, M.F.
登録日2020-02-19
公開日2020-04-08
最終更新日2020-09-30
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans.
Nat Commun, 11, 2020
8K5O
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BU of 8k5o by Molmil
Cryo-EM structure of the RC-LH core comples from Halorhodospira halochloris
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-O-octyl-beta-D-glucopyranose, ...
著者Wang, G.-L, Qi, C.-H, Yu, L.-J.
登録日2023-07-22
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (2.42 Å)
主引用文献Structural insights into the unusual core photocomplex from a triply extremophilic purple bacterium, Halorhodospira halochloris.
J Integr Plant Biol, 2024
8KEM
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BU of 8kem by Molmil
PKS domains-fused AmpC EC2
分子名称: SDR family NAD(P)-dependent oxidoreductase,Beta-lactamase
著者Son, S.Y, Bae, D.W, Cha, S.S.
登録日2023-08-12
公開日2024-06-05
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.76998281 Å)
主引用文献Structural investigation of the docking domain assembly from trans-AT polyketide synthases.
Structure, 2024
6BJO
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BU of 6bjo by Molmil
PICK1 PDZ domain in complex with the small molecule inhibitor BIO124.
分子名称: (2S)-({4-(4-bromophenyl)-1-[1-(tert-butoxycarbonyl)-L-prolyl]piperidine-4-carbonyl}amino)(cyclopentyl)acetic acid, PRKCA-binding protein
著者Marcotte, D.J.
登録日2017-11-06
公開日2018-01-10
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure.
Protein Sci., 27, 2018
6BJN
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BU of 6bjn by Molmil
PICK1 PDZ domain in complex with the class I PDZ binding motif QSAV
分子名称: PRKCA-binding protein
著者Marcotte, D.J.
登録日2017-11-06
公開日2018-01-10
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure.
Protein Sci., 27, 2018
6GAW
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BU of 6gaw by Molmil
Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the complete 55S ribosome.
分子名称: 12S ribosomal RNA, mitochondrial, 16S ribosomal RNA, ...
著者Kummer, E, Leibundgut, M, Boehringer, D, Ban, N.
登録日2018-04-13
公開日2018-08-22
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.
Nature, 560, 2018
8P2E
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BU of 8p2e by Molmil
Homotypic interacting B1 fab bound to Chondroitin Sulfate A
分子名称: B1 fab heavy, B1 fab light
著者Raghavan, S.S.R, Dagil, R, Wang, K.T, Salanti, A.
登録日2023-05-16
公開日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of homotypic B1 fabs bound to Chondroiting Sulfate A
To Be Published
8OIP
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BU of 8oip by Molmil
28S mammalian mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA
分子名称: 12S rRNA, 28S ribosomal protein S15, mitochondrial, ...
著者Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
登録日2023-03-23
公開日2023-05-24
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023

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