6WX5

Adducts formed after 3 weeks in the reaction of chlorido[chlorido(2,2'-((2-([2,2':6',2''-Terpyridin]-4'-yloxy)ethyl)azanediyl)bis(ethan-1-ol))platinum(II)] with HEWL

Summary for 6WX5

• Entry DOI: 10.2210/pdb6wx5/pdb
• Descriptor: Lysozyme, SODIUM ION, ACETATE ION, ... (5 entities in total)
• Functional Keywords: metal-based, anticancer, platinum, terpyridine, lysozyme, metallodrug, hydrolase
• Biological source: Gallus gallus (Chicken)
• Total number of polymer chains: 1
• Total formula weight: 14608.27

Authors

Sullivan, M.P.,Hartinger, C.G.,Goldstone, D.C. (deposition date: 2020-05-09, release date: 2021-02-10, Last modification date: 2023-10-18)

• Primary citation: Adams, M.,Sullivan, M.P.,Tong, K.K.H.,Goldstone, D.C.,Hanif, M.,Jamieson, S.M.F.,Hartinger, C.G.; Mustards-Derived Terpyridine-Platinum Complexes as Anticancer Agents: DNA Alkylation vs Coordination.; Inorg.Chem., 60:2414-2424, 2021; PubMed: 33497565; DOI: 10.1021/acs.inorgchem.0c03317

Experimental method

X-RAY DIFFRACTION (1.3 Å)