7WIW

Cryo-EM structure of Mycobacterium tuberculosis irtAB complexed with ATP in an occluded conformation

Summary for 7WIW

Entry DOI	10.2210/pdb7wiw/pdb
EMDB information	32538
Descriptor	Mycobactin import ATP-binding/permease protein IrtB, Mycobactin import ATP-binding/permease protein IrtA, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywords	irtab, abc exporter-liker importer, iron-loaded siderophore, mycobacterium tuberculosis, membrane protein
Biological source	Mycobacterium tuberculosis H37Rv More
Total number of polymer chains	2
Total formula weight	155166.09
Authors	Zhang, B.,Sun, S.,Yang, H.,Rao, Z. (deposition date: 2022-01-05, release date: 2023-01-25, Last modification date: 2024-04-10)
Primary citation	Sun, S.,Gao, Y.,Yang, X.,Yang, X.,Hu, T.,Liang, J.,Xiong, Z.,Ran, Y.,Ren, P.,Bai, F.,Guddat, L.W.,Yang, H.,Rao, Z.,Zhang, B. Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB. Protein Cell, 14:448-458, 2023 Cited by PubMed: 36882106 DOI: 10.1093/procel/pwac060 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.12 Å)

Structure validation