7Q49

Local refinement structure of the N-domain of full-length, monomeric, soluble somatic angiotensin I-converting enzyme

Summary for 7Q49

• Entry DOI: 10.2210/pdb7q49/pdb
• Related: 7Q3Y 7Q4C 7Q4D 7Q4E
• EMDB information: 13797 13799 13801 13802 13803 13804
• Descriptor: Angiotensin-converting enzyme, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: zinc metalloprotease dicarboxypeptidase glycoprotein, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 144435.78

Authors

Lubbe, L.,Sewell, B.T.,Sturrock, E.D. (deposition date: 2021-10-29, release date: 2022-07-20, Last modification date: 2022-08-24)

• Primary citation: Lubbe, L.,Sewell, B.T.,Woodward, J.D.,Sturrock, E.D.; Cryo-EM reveals mechanisms of angiotensin I-converting enzyme allostery and dimerization.; Embo J., 41:e110550-e110550, 2022; PubMed: 35818993; DOI: 10.15252/embj.2021110550

Experimental method

ELECTRON MICROSCOPY (3.72 Å)