1YLA

Ubiquitin-conjugating enzyme E2-25 kDa (Huntington interacting protein 2)

Summary for 1YLA

Entry DOI	10.2210/pdb1yla/pdb
Descriptor	Ubiquitin-conjugating enzyme E2-25 kDa (2 entities in total)
Functional Keywords	ubiquitin, ubiquitin- conjugating enzyme, ligase, structural genomics, sgc, structural genomics consortium
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm (By similarity): P61086
Total number of polymer chains	2
Total formula weight	45149.44
Authors	Choe, J.,Avvakumov, G.V.,Newman, E.M.,Mackenzie, F.,Kozieradzki, I.,Bochkarev, A.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Dhe-paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2005-01-19, release date: 2005-02-01, Last modification date: 2023-08-23)
Primary citation	Ko, S.,Kang, G.B.,Song, S.M.,Lee, J.-G.,Shin, D.Y.,Yun, J.-H.,Sheng, Y.,Cheong, C.,Jeon, Y.H.,Jung, Y.-K.,Arrowsmith, C.H.,Avvakumov, G.V.,Dhe-Paganon, S.,Yoo, Y.J.,Eom, S.H.,Lee, W. Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity J.Biol.Chem., 285:36070-36080, 2010 Cited by PubMed: 20826778 DOI: 10.1074/jbc.M110.145219 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation