PDB: 245396 件ウェブページステータス検索Chemie searchBIRD

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2PNG	Type I rat fatty acid synthase acyl carrier protein (ACP) domain 分子名称: Fatty acid synthase (EC 2.3.1.85) 著者 Ploskon, E.A, Arthur, C.J, Evans, S.E, Williams, C, Crosby, J, Crump, M.P. 登録日 2007-04-24 公開日 2007-06-05 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A Mammalian type I Fatty Acid synthase acyl carrier protein domain does not sequester acyl chains. J.Biol.Chem., 283, 2008
1MH5	The Structure Of The Complex Of The Fab Fragment Of The Esterolytic Antibody MS6-164 and A Transition-State Analog 分子名称: IMMUNOGLOBULIN MS6-164, N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE, SULFATE ION 著者 Ruzheinikov, S.N, Muranova, T.A, Sedelnikova, S.E, Partridge, L.J, Blackburn, G.M, Murray, I.A, Kakinuma, H, Takashi, N, Shimazaki, K, Sun, J, Nishi, Y, Rice, D.W. 登録日 2002-08-19 公開日 2003-09-23 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity J.Mol.Biol., 332, 2003
3UIO	Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II 分子名称: E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... 著者 Gareau, J.R, Reverter, D, Lima, C.D. 登録日 2011-11-05 公開日 2011-12-28 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
4CEQ	Interrogating HIV integrase for compounds that bind- a SAMPL challenge 分子名称: (2S)-6-[[[2-(cyclohexylmethylcarbamoyl)phenyl]methyl-methyl-amino]methyl]-2-(3-hydroxy-3-oxopropyl)-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid, ACETATE ION, CHLORIDE ION, ... 著者 Peat, T.S. 登録日 2013-11-11 公開日 2013-11-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Interrogating HIV Integrase for Compounds that Bind- a Sampl Challenge. J.Comput.Aided Mol.Des., 28, 2014
3BS3	Crystal structure of a putative DNA-binding protein from Bacteroides fragilis 分子名称: 1,2-ETHANEDIOL, Putative DNA-binding protein, SULFATE ION 著者 Cuff, M.E, Bigelow, L, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2007-12-21 公開日 2008-01-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The structure of a putative DNA-binding protein from Bacteroides fragilis. TO BE PUBLISHED
1MJN	Crystal Structure of the intermediate affinity aL I domain mutant 分子名称: Integrin alpha-L, MAGNESIUM ION 著者 Shimaoka, M, Xiao, T, Liu, J.H, Yang, Y.T, Dong, Y.C, Jun, C.D, McCormack, A, Zhang, R.G, Wang, J.H, Springer, T.A. 登録日 2002-08-28 公開日 2003-01-28 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structures of the alphaL I Domain and its Complex with ICAM-1 reveal a Shape-shifting Pathway for Integrin Regulation Cell(Cambridge,Mass.), 112, 2003
3BWF	Crystal structure of the human Pim1 in complex with an osmium compound 分子名称: PYRIDOCARBAZOLE CYCLOPENTADIENYL OS(CO) COMPLEX, Proto-oncogene serine/threonine-protein kinase Pim-1, SULFATE ION 著者 Maksimoska, J, Filippakopoulos, P, Knapp, S, Meggers, E. 登録日 2008-01-09 公開日 2008-06-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Similar biological activities of two isostructural ruthenium and osmium complexes. Chemistry, 14, 2008
3UIE	Crystal structure of adenosine 5'-phosphosulfate kinase from Arabidopsis Thaliana in Complex with AMPPNP and APS 分子名称: ADENOSINE-5'-PHOSPHOSULFATE, Adenylyl-sulfate kinase 1, chloroplastic, ... 著者 Ravilious, G.E, Jez, J.M. 登録日 2011-11-04 公開日 2012-01-25 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.794 Å) 主引用文献 Structural basis and evolution of redox regulation in plant adenosine-5'-phosphosulfate kinase. Proc.Natl.Acad.Sci.USA, 109, 2012
1UG1	SH3 domain of Hypothetical protein BAA76854.1 分子名称: KIAA1010 protein 著者 Nagata, T, Muto, Y, Kamewari, Y, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Ohara, O, Nagase, T, Kikuno, R, Nakayama, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-06-11 公開日 2003-12-11 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 NMR structure of SH3 domain of Hypothetical protein BAA76854.1 To be Published
1S9R	CRYSTAL STRUCTURE OF ARGININE DEIMINASE COVALENTLY LINKED WITH A REACTION INTERMEDIATE 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ARGININE, Arginine deiminase, ... 著者 Das, K, Buttler, G.H, Kwiatkowski, V, Clark Jr, A.D, Yadav, P, Arnold, E. 登録日 2004-02-05 公開日 2004-04-13 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structures of Arginine Deiminase with Covalent Reaction Intermediates: Implications for Catalytic Mechanism Structure, 12, 2004
2Q9Y	Trichodiene synthase: Complex with Mg, inorganic pyrophosphate, and benzyl triethyl ammonium cation 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, ... 著者 Vedula, L.S, Zhao, Y, Coates, R.M, Koyama, T, Cane, D.E, Christianson, D.W. 登録日 2007-06-14 公開日 2008-04-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Exploring biosynthetic diversity with trichodiene synthase. Arch.Biochem.Biophys., 466, 2007
4KJM	Crystal structure of the Staphylococcus aureus protein (NP_646141.1, domain 3912-4037) similar to streptococcal adhesins emb and ebhA/ebhB 分子名称: ACETATE ION, CHLORIDE ION, Extracellular matrix-binding protein ebh, ... 著者 Cymborowski, M, Shabalin, I.G, Joachimiak, G, Chruszcz, M, Gornicki, P, Zhang, R, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2013-05-03 公開日 2013-05-29 最終更新日 2025-10-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the Staphylococcus aureus protein (NP_646141.1, domain 3912-4037) similar to streptococcal adhesins emb and ebhA/ebhB To be Published
4KCU	Pyruvate kinase (PYK) from Trypanosoma brucei soaked with D-Malate 分子名称: 2,6-di-O-phosphono-beta-D-fructofuranose, D-MALATE, MAGNESIUM ION, ... 著者 Zhong, W, Morgan, H.P, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. 登録日 2013-04-24 公開日 2014-01-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Pyruvate kinases have an intrinsic and conserved decarboxylase activity. Biochem.J., 458, 2014
4E6D	JAK2 kinase (JH1 domain) triple mutant in complex with compound 7 分子名称: 3-[(3R)-3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)piperidin-1-yl]-3-oxopropanenitrile, GLYCEROL, Tyrosine-protein kinase JAK2 著者 Murray, J.M. 登録日 2012-03-15 公開日 2012-05-30 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors. J.Med.Chem., 55, 2012
3UL2	Galactose-specific lectin from Dolichos lablab in P6522 space group 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Shetty, K.N, Latha, V.L, Rao, R.N, Nadimpalli, S.K, Suguna, K. 登録日 2011-11-10 公開日 2012-11-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Affinity of a galactose-specific legume lectin from Dolichos lablab to adenine revealed by X-ray cystallography. Iubmb Life, 65, 2013
4KFO	Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors 分子名称: 1,2-ETHANEDIOL, N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}imidazo[1,2-a]pyridine-6-carboxamide, Nicotinamide phosphoribosyltransferase, ... 著者 Zheng, X, Bauer, P, Baumeister, T, Buckmelter, A.J, Caligiuri, M, Clodfelter, K.H, Han, B, Ho, Y, Kley, N, Lin, J, Reynolds, D.J, Sharma, G, Smith, C.C, Wang, Z, Dragovich, P.S, Gunzner-Tosteb, J, Liederer, B.M, Ly, J, O'Brien, T, Oh, A, Wang, L, Wang, W, Xiao, Y, Zak, M, Zhao, G, Yuen, P, Bair, K.W. 登録日 2013-04-27 公開日 2013-05-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (nampt) inhibitors. J.Med.Chem., 56, 2013
1NX9	Acetobacter turbidans alpha-amino acid ester hydrolase S205A mutant complexed with ampicillin 分子名称: (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, GLYCEROL, alpha-amino acid ester hydrolase 著者 Barends, T.R.M, Polderman-Tijmes, J.J, Jekel, P.A, Janssen, D.B, Dijkstra, B.W. 登録日 2003-02-10 公開日 2004-03-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Acetobacter turbidans {alpha}-Amino Acid Ester Hydrolase: HOW A SINGLE MUTATION IMPROVES AN ANTIBIOTIC-PRODUCING ENZYME. J.Biol.Chem., 281, 2006
4Q1N	Structure-based design of 4-hydroxy-3,5-substituted piperidines as direct renin inhibitors 分子名称: (3S,4R,5R)-N-cyclopropyl-N'-[(2R)-1-ethoxy-4-methylpentan-2-yl]-4-hydroxy-N-[5-(propan-2-yl)pyridin-2-yl]piperidine-3,5-dicarboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... 著者 Schiering, N, D'Arcy, A, Irie, O, Yokokawa, F. 登録日 2014-04-04 公開日 2014-08-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structure-based design of substituted piperidines as a new class of highly efficacious oral direct Renin inhibitors. ACS Med Chem Lett, 5, 2014
3CCN	X-ray structure of c-Met with triazolopyridazine inhibitor. 分子名称: 4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]phenol, Hepatocyte growth factor receptor 著者 Abrecht, B.K, Harmange, J.-C, Bauer, D, Dussault, I, long, A, Bellon, S.F. 登録日 2008-02-26 公開日 2008-04-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase. J.Med.Chem., 51, 2008
1IZY	Crystal structure of Hsp31 分子名称: Hsp31 著者 Cha, S.S, Lee, S.J. 登録日 2002-10-16 公開日 2003-10-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of human DJ-1 and Escherichia coli Hsp31, which share an evolutionarily conserved domain J.Biol.Chem., 278, 2003
4KQF	Crystal structure of CobT E174A complexed with adenine 分子名称: 1,2-ETHANEDIOL, ADENINE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, ... 著者 Chan, C.H, Newmister, S.A, Taylor, K.C, Claas, K.R, Rayment, I, Escalante-Semerena, J.C. 登録日 2013-05-15 公開日 2014-03-12 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Dissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica. Biochim.Biophys.Acta, 1840, 2014
3OQJ	Crystal structure of B. licheniformis CDPS yvmC-BLIC in complex with CAPSO 分子名称: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, Putative uncharacterized protein yvmC 著者 Bonnefond, L, Arai, T, Suzuki, T, Ishitani, R, Nureki, O. 登録日 2010-09-03 公開日 2011-02-23 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.399 Å) 主引用文献 Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog. Proc.Natl.Acad.Sci.USA, 108, 2011
2D74	Crystal structure of translation initiation factor aIF2betagamma heterodimer 分子名称: Translation initiation factor 2 beta subunit, Translation initiation factor 2 gamma subunit, ZINC ION 著者 Sokabe, M, Yao, M, Sakai, N, Toya, S, Tanaka, I. 登録日 2005-11-16 公開日 2006-07-25 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region. Proc.Natl.Acad.Sci.USA, 103, 2006
4K0S	Structure of HCAIX mimic (HCAII with 5 mutations in active site) in complex with acetazolamide 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, ZINC ION 著者 Biswas, S, McKenna, R. 登録日 2013-04-04 公開日 2014-04-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Developing isoform specific inhibitors against hCAIX using CAIX mimic To be Published
1S0M	Crystal structure of a Benzo[a]pyrene Diol Epoxide adduct in a ternary complex with a DNA polymerase 分子名称: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*T)-3', ... 著者 Ling, H, Sayer, J.M, Boudsocq, F, Plosky, B.S, Woodgate, R, Yang, W. 登録日 2003-12-31 公開日 2004-03-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. Proc.Natl.Acad.Sci.USA, 101, 2004

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