7PYV
| Crystal structure of human UBA6 in complex with the ubiquitin-like modifier FAT10 | 分子名称: | UBD, Ubiquitin-like modifier-activating enzyme 6,Ubiquitin-like modifier-activating enzyme 1,Ubiquitin-like modifier-activating enzyme 6 | 著者 | Li, S, Truongvan, N, Schindelin, H. | 登録日 | 2021-10-11 | 公開日 | 2022-08-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | 主引用文献 | Structures of UBA6 explain its dual specificity for ubiquitin and FAT10. Nat Commun, 13, 2022
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6RPQ
| Crystal structure of PhoCDC21-1 intein | 分子名称: | Ubiquitin-like protein SMT3,1108aa long hypothetical cell division control protein | 著者 | Beyer, H.M, Mikula, K.M, Iwai, H. | 登録日 | 2019-05-14 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.654 Å) | 主引用文献 | Crystal structures of CDC21-1 inteins from hyperthermophilic archaea reveal the selection mechanism for the highly conserved homing endonuclease insertion site. Extremophiles, 23, 2019
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6SIS
| Crystal structure of macrocyclic PROTAC 1 in complex with the second bromodomain of human Brd4 and pVHL:ElonginC:ElonginB | 分子名称: | Bromodomain-containing protein 4, Elongin-B, Elongin-C, ... | 著者 | Hughes, S.J, Testa, A, Ciulli, A. | 登録日 | 2019-08-10 | 公開日 | 2019-12-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure-Based Design of a Macrocyclic PROTAC. Angew.Chem.Int.Ed.Engl., 59, 2020
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6TBM
| Structure of SAGA bound to TBP, including Spt8 and DUB | 分子名称: | Polyubiquitin-B, SAGA-associated factor 11, Spt20, ... | 著者 | Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A. | 登録日 | 2019-11-01 | 公開日 | 2020-02-12 | 最終更新日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (20 Å) | 主引用文献 | Structure of SAGA and mechanism of TBP deposition on gene promoters. Nature, 577, 2020
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6TNF
| Structure of monoubiquitinated FANCD2 in complex with FANCI and DNA | 分子名称: | DNA (33-MER), FANCD2, Fanconi anemia complementation group I, ... | 著者 | Alcon, P, Shakeel, S, Passmore, L.A. | 登録日 | 2019-12-07 | 公開日 | 2020-02-19 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair. Nat.Struct.Mol.Biol., 27, 2020
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6RYA
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6TUV
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6UKM
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6TXB
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6UKU
| STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 3 | 分子名称: | 4,4'-[propane-1,3-diylbis(6-methoxy-1-benzothiene-5,2-diyl)]bis(4-oxobutanoic acid), fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain | 著者 | Lesburg, C.A. | 登録日 | 2019-10-06 | 公開日 | 2020-08-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | An orally available non-nucleotide STING agonist with antitumor activity. Science, 369, 2020
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6UL0
| STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 4 | 分子名称: | 4-{5-[(1Z)-3-{[2-(3-carboxypropanoyl)-6-methoxy-1-benzothiophen-5-yl]oxy}prop-1-en-1-yl]-6-methoxy-1-benzothiophen-2-yl}-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain | 著者 | Lesburg, C.A. | 登録日 | 2019-10-06 | 公開日 | 2020-08-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | An orally available non-nucleotide STING agonist with antitumor activity. Science, 369, 2020
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6P59
| Crystal structure of SIVrcm Vif-CBFbeta-ELOB-ELOC complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Core-binding factor subunit beta, Elongin-B, ... | 著者 | Binning, J.M, Chesarino, N.M, Emerman, M, Gross, J.D. | 登録日 | 2019-05-29 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.942214 Å) | 主引用文献 | Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism. Cell Host Microbe, 26, 2019
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3GZN
| Structure of NEDD8-activating enzyme in complex with NEDD8 and MLN4924 | 分子名称: | NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ... | 著者 | Sintchak, M.D. | 登録日 | 2009-04-07 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ. Mol.Cell, 37, 2010
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6PGV
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7MC9
| X-RAY STRUCTURE OF PEDV PAPAIN-LIKE PROTEASE 2 bound to UB-PA | 分子名称: | 3C-like proteinase, Ubiquitin, ZINC ION, ... | 著者 | Durie, I.A, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D. | 登録日 | 2021-04-01 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.099 Å) | 主引用文献 | Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin Acta Cryst. D, 77, 2021
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7MIC
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6Q00
| TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 1 | 分子名称: | POTASSIUM ION, Tyrosyl-DNA phosphodiesterase 2, Ubiquitin | 著者 | Schellenberg, M.J, Krahn, J.M, Williams, R.S. | 登録日 | 2019-08-01 | 公開日 | 2020-04-29 | 最終更新日 | 2020-06-24 | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | 主引用文献 | Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2. Nucleic Acids Res., 48, 2020
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6PZV
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6Q01
| TDP2 UBA Domain Bound to Ubiquitin at 0.85 Angstroms Resolution, Crystal Form 2 | 分子名称: | 1,2-ETHANEDIOL, BENZOIC ACID, MAGNESIUM ION, ... | 著者 | Schellenberg, M.J, Krahn, J.M, Williams, R.S. | 登録日 | 2019-08-01 | 公開日 | 2020-04-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (0.851 Å) | 主引用文献 | Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2. Nucleic Acids Res., 48, 2020
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7NPI
| Crystal structure of Mindy2 (C266A) in complex with Lys48-linked penta-ubiquitin (K48-Ub5) | 分子名称: | CHLORIDE ION, Polyubiquitin-C, SODIUM ION, ... | 著者 | Lange, S.M, Armstrong, L.A, Kulathu, Y. | 登録日 | 2021-02-26 | 公開日 | 2021-09-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Mol.Cell, 81, 2021
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3IHP
| Covalent Ubiquitin-Usp5 Complex | 分子名称: | CHLORIDE ION, ETHANAMINE, Ubiquitin, ... | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2009-07-30 | 公開日 | 2009-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Covalent Ubiquitin-Usp5 Complex To be Published
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3IFW
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7M3Q
| Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, ... | 著者 | Chowdhury, A, Singer, A.U, Ogunjimi, A.A, Teyra, J, Zhang, W, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-03-18 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV) To be published
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6O83
| S. pombe ubiquitin E1~ubiquitin-AMP tetrahedral intermediate mimic | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, ... | 著者 | Hann, Z.S, Lima, C.D. | 登録日 | 2019-03-08 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.153 Å) | 主引用文献 | Structural basis for adenylation and thioester bond formation in the ubiquitin E1. Proc.Natl.Acad.Sci.USA, 116, 2019
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6O82
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