PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4DUT	The structure of nucleoside diphosphate kinase (NDK) from Burkholderia thailandensis 分子名称: CHLORIDE ION, Nucleoside diphosphate kinase, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-02-22 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
4E1H	Fragment of human prion protein 分子名称: CITRIC ACID, FE (III) ION, Major prion protein 著者 Apostol, M.I, Perry, K, Surewicz, W.K. 登録日 2012-03-06 公開日 2013-03-06 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of a human prion protein fragment reveals a motif for oligomer formation. J.Am.Chem.Soc., 135, 2013
4MOU	Crystal Structure of an Enoyl-CoA Hydratase/Isomerase Family Member, NYSGRC target 028282 分子名称: CACODYLATE ION, Enoyl-CoA hydratase/isomerase family protein 著者 Chapman, H.C, Cooper, D.R, Geffken, K.T, Cymborowski, M.T, Osinski, T, Stead, M, Hillerich, B, Ahmed, M, Bonanno, J.B, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-09-12 公開日 2013-09-25 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of an Enoyl-CoA Hydratase/Isomerase Family Member, NYSGRC target 028282 To be Published
4DX2	Crystal structure of the human TRPV4 ankyrin repeat domain 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Transient receptor potential cation channel subfamily V member 4, ... 著者 Inada, H, Gaudet, R. 登録日 2012-02-27 公開日 2012-07-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel. Biochemistry, 51, 2012
4DS3	Crystal Structure of Phosphoribosylglycinamide formyltransferase from Brucella melitensis 分子名称: CHLORIDE ION, GLYCEROL, Phosphoribosylglycinamide formyltransferase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-02-17 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of Phosphoribosylglycinamide formyltransferase from Brucella melitensis TO BE PUBLISHED
4DS7	Crystal structure of yeast calmodulin bound to the C-terminal fragment of spindle pole body protein Spc110 分子名称: Calmodulin, GLYCEROL, STRONTIUM ION, ... 著者 Klenchin, V.A, Rayment, I. 登録日 2012-02-18 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling. Mol.Biol.Cell, 28, 2017
4MPQ	Crystal structure of1-pyrroline-4-hydroxy-2-carboxylate deaminase from Brucella melitensis ATCC 23457 分子名称: 1,2-ETHANEDIOL, Dihydrodipicolinate synthetase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-09-13 公開日 2013-09-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of1-pyrroline-4-hydroxy-2-carboxylate deaminase from Brucella melitensis ATCC 23457 To be Published
4DSG	Crystal Structure of oxidized UDP-Galactopyranose mutase 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, UDP-galactopyranose mutase, ... 著者 Singh, H, Dhatwalia, R, Tanner, J.J. 登録日 2012-02-18 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.249 Å) 主引用文献 Crystal Structures of Trypanosoma cruzi UDP-Galactopyranose Mutase Implicate Flexibility of the Histidine Loop in Enzyme Activation. Biochemistry, 51, 2012
4DSZ	Crystal Structure of DPP-IV with Compound C2 分子名称: (2R)-4-[4-(3-methylphenyl)-1H-1,2,3-triazol-1-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine, Dipeptidyl peptidase 4 著者 Xiong, B, Zhu, L.R, Chen, D.Q, Zhao, Y.L, Jiang, F, Shen, J.K. 登録日 2012-02-20 公開日 2013-02-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal Structure of DPP-IV with Compound C2 To be Published
4DZ2	Crystal structure of a Peptidyl-prolyl cis-trans isomerase with surface mutation R92G from Burkholderia pseudomallei complexed with FK506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-02-29 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob.Agents Chemother., 58, 2014
4MLR	dihydrodipicolinate synthase from C. jejuni, Y110F mutation with pyruvate and Lysine 分子名称: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... 著者 Conly, C.J.T. 登録日 2013-09-06 公開日 2015-01-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry, 53, 2014
4DW3	Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 5'-CMP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYTIDINE-5'-MONOPHOSPHATE, ... 著者 Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. 登録日 2012-02-24 公開日 2012-05-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. Structure, 20, 2012
4MW7	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(5-chloro-2-ethoxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1469) 分子名称: 1-{3-[(5-chloro-2-ethoxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-09-24 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
4DWA	Crystal structure of an active-site mutant of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a CpUpC trinucleotide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ... 著者 Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. 登録日 2012-02-24 公開日 2012-05-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. Structure, 20, 2012
4MXC	Crystal structure of CMET in complex with novel inhibitor 分子名称: Hepatocyte growth factor receptor, N-(3-fluoro-4-{[2-({3-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 著者 Liu, Q.F, Chen, T.T, Xu, Y.C. 登録日 2013-09-26 公開日 2014-10-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.632 Å) 主引用文献 Discovery of Anilinopyrimidines as Dual Inhibitors of c-Met and VEGFR-2: Synthesis, SAR, and Cellular Activity ACS MED.CHEM.LETT., 5, 2014
4MIN	Crystal Structure of myo-inositol dehydrogenase from Lactobacillus casei with bound cofactor NAD 分子名称: GLYCEROL, Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Bertwistle, D, Sanders, D.A.R, Palmer, D.R.J. 登録日 2013-09-01 公開日 2015-03-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of myo-inositol dehydrogenase from Lactobacillus casei with bound cofactor NAD To be Published
4MK0	Crystal structure of G protein-coupled receptor kinase 2 in complex with a a rationally designed paroxetine derivative 分子名称: 5-{[(3S,4R)-4-(4-fluorophenyl)piperidin-3-yl]methoxy}-1H-isoindol-1-one, Beta-adrenergic receptor kinase 1, GLYCEROL, ... 著者 Homan, K.T, Tesmer, J.J.G. 登録日 2013-09-04 公開日 2014-01-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and functional analysis of g protein-coupled receptor kinase inhibition by paroxetine and a rationally designed analog. Mol.Pharmacol., 85, 2014
4MKR	Structure of the apo form of a Zingiber officinale double bond reductase 分子名称: Zingiber officinale double bond reductase 著者 Buratto, J, Langlois d'Estaintot, B, Granier, T, Gallois, B, Willis, M.A, Sang, Y, Flores-Sanchez, I.J, Gang, D.R. 登録日 2013-09-05 公開日 2014-09-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structure of Zingiber officinale double bond reductase To be Published
4DZ4	X-ray crystal structure of a hypothetical Agmatinase from Burkholderia thailandensis 分子名称: 1,2-ETHANEDIOL, Agmatinase, MANGANESE (II) ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-02-29 公開日 2012-03-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
4LP6	Crystal Structure of Human Carbonic Anhydrase II in complex with a quinoline oligoamide foldamer 分子名称: 8-({[4-(3-aminopropoxy)-8-({[4-hydroxy-8-({[4-(2-methylpropoxy)-8-({[4-(3-{[(4-sulfamoylbenzoyl)amino]methyl}phenoxy)butyl]carbamoyl}amino)quinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)quinolin-2-yl]carbonyl}amino)-4-(carboxymethoxy)quinoline-2-carboxylic acid, Carbonic anhydrase 2, ZINC ION 著者 Buratto, J, Granier, T, Langlois D'estaintot, B, Huc, I, Gallois, B. 登録日 2013-07-15 公開日 2013-10-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure of a complex formed by a protein and a helical aromatic oligoamide foldamer at 2.1 angstrom resolution. Angew.Chem.Int.Ed.Engl., 53, 2014
4LZD	Human DNA polymerase mu- Apoenzyme 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DNA-directed DNA/RNA polymerase mu, ... 著者 Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. 登録日 2013-07-31 公開日 2014-02-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Sustained active site rigidity during synthesis by human DNA polymerase mu. Nat.Struct.Mol.Biol., 21, 2014
4M16	Crystal Structure of the N-terminal Fic Domain of Bartonella effector protein (Bep); substrate of VirB T4SS (VirB-translocated Bep effector protein) from Bartonella sp. AR 15-3 分子名称: 1,2-ETHANEDIOL, Bartonella effector protein (Bep) substrate of VirB T4SS 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-08-02 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Evolutionary Diversification of Host-Targeted Bartonella Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module. Microorganisms, 9, 2021
4M1E	Crystal structure of purine nucleoside phosphorylase I from Planctomyces limnophilus DSM 3776, NYSGRC Target 029364. 分子名称: ADENINE, PYRIDINE-2-CARBOXYLIC ACID, Purine nucleoside phosphorylase, ... 著者 Malashkevich, V.N, Bonanno, J.B, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-08-02 公開日 2013-08-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of purine nucleoside phosphorylase I from Planctomyces limnophilus DSM 3776, NYSGRC Target 029364. To be Published
4M2X	Mycobacterium tuberculosis dihydrofolate reductase complexed with trimetrexate (TMQ) 分子名称: ACETATE ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Jung, H, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2013-08-05 公開日 2014-11-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Selective inhibitors for dihydrofolate reductase from mycobacterium tuberculosis To be Published
4M3D	Rapid and efficient design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging and linking approaches 分子名称: 4-{3-[(phenylsulfonyl)amino]prop-1-yn-1-yl}-N-(3,3,3-trifluoropropyl)benzamide, HTH-type transcriptional regulator EthR 著者 Villemagne, B, Flipo, M, Blondiaux, N, Crauste, C, Malaquin, S, Leroux, F, Piveteau, C, Villeret, V, Brodin, P, Villoutreix, B, Sperandio, O, Wohlkonig, A, Wintjens, R, Deprez, B, Baulard, A, Willand, N. 登録日 2013-08-06 公開日 2014-06-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches. J.Med.Chem., 57, 2014

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