4DX2

Crystal structure of the human TRPV4 ankyrin repeat domain

Summary for 4DX2

Entry DOI	10.2210/pdb4dx2/pdb
Related	4DX1
Descriptor	Transient receptor potential cation channel subfamily V member 4, beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	ankyrin repeat, ion channel, membrane, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	59692.92
Authors	Inada, H.,Gaudet, R. (deposition date: 2012-02-27, release date: 2012-07-18, Last modification date: 2024-02-28)
Primary citation	Inada, H.,Procko, E.,Sotomayor, M.,Gaudet, R. Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel. Biochemistry, 51:6195-6206, 2012 Cited by PubMed: 22702953 DOI: 10.1021/bi300279b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation