4DW3

Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 5'-CMP

Summary for 4DW3

Entry DOI	10.2210/pdb4dw3/pdb
Related	4DVK 4DVL 4DVN
Descriptor	E(rns) glycoprotein, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	virus glycoprotein, t2 ribonuclease, viral protein
Biological source	Bovine viral diarrhea virus (BVDV)
Total number of polymer chains	2
Total formula weight	43717.87
Authors	Krey, T.,Bontems, F.,Vonrhein, C.,Vaney, M.-C.,Bricogne, G.,Ruemenapf, T.,Rey, F.A. (deposition date: 2012-02-24, release date: 2012-05-23, Last modification date: 2023-09-13)
Primary citation	Krey, T.,Bontems, F.,Vonrhein, C.,Vaney, M.C.,Bricogne, G.,Rumenapf, T.,Rey, F.A. Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. Structure, 20:862-873, 2012 Cited by PubMed: 22579253 DOI: 10.1016/j.str.2012.03.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation