1TJH
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![BU of 1tjh by Molmil](/molmil-images/mine/1tjh) | Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 11mer epitope | 分子名称: | 1,2-ETHANEDIOL, Envelope glycoprotein GP41, ISOPROPYL ALCOHOL, ... | 著者 | Ofek, G, Tang, M, Sambor, A, Katinger, H, Mascola, J.R, Wyatt, R, Kwong, P.D. | 登録日 | 2004-06-04 | 公開日 | 2004-10-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope J.Virol., 78, 2004
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1W1A
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![BU of 1w1a by Molmil](/molmil-images/mine/1w1a) | Structure of Bacillus subtilis PdaA in complex with NAG, a family 4 Carbohydrate esterase. | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, CADMIUM ION, GLYCEROL, ... | 著者 | Blair, D.E, van Aalten, D.M.F. | 登録日 | 2004-06-18 | 公開日 | 2005-01-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structures of Bacillus subtilis PdaA, a family 4 carbohydrate esterase, and a complex with N-acetyl-glucosamine. FEBS Lett., 570, 2004
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1VJ9
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![BU of 1vj9 by Molmil](/molmil-images/mine/1vj9) | Urokinase Plasminogen Activator B-Chain-JT464 Complex | 分子名称: | N-(BENZYLSULFONYL)-L-SERYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}-O-BENZYL-L-SERINAMIDE, SULFATE ION, plasminogen activator, ... | 著者 | Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J. | 登録日 | 2004-02-03 | 公開日 | 2004-06-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents J.Biol.Chem., 279, 2004
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2GAA
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2JEW
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![BU of 2jew by Molmil](/molmil-images/mine/2jew) | |
2JH6
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![BU of 2jh6 by Molmil](/molmil-images/mine/2jh6) | Human Thrombin Hirugen Inhibitor complex | 分子名称: | 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE, CALCIUM ION, HIRUDIN IIIA, ... | 著者 | Senger, S, Chan, C, Convery, M.A, Hubbard, J.A, Young, R.J, Shah, G.P, Watson, N.S. | 登録日 | 2007-02-20 | 公開日 | 2007-05-08 | 最終更新日 | 2013-08-07 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Sulfonamide-Related Conformational Effects and Their Importance in Structure-Based Design. Bioorg.Med.Chem.Lett., 17, 2007
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2JJV
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![BU of 2jjv by Molmil](/molmil-images/mine/2jjv) | Structure of human signal regulatory protein (sirp) beta(2) | 分子名称: | CHLORIDE ION, SIGNAL-REGULATORY PROTEIN BETA 1., SULFATE ION | 著者 | Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. | 登録日 | 2008-04-22 | 公開日 | 2008-08-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47. Mol.Cell, 31, 2008
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2LS0
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2L94
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![BU of 2l94 by Molmil](/molmil-images/mine/2l94) | Structure of the HIV-1 frameshift site RNA bound to a small molecule inhibitor of viral replication | 分子名称: | N'-{(Z)-amino[4-(amino{[3-(dimethylammonio)propyl]iminio}methyl)phenyl]methylidene}-N,N-dimethylpropane-1,3-diaminium, RNA_(45-MER) | 著者 | Marcheschi, R.J, Tonelli, M, Kumar, A, Butcher, S.E. | 登録日 | 2011-01-29 | 公開日 | 2011-06-15 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the HIV-1 Frameshift Site RNA Bound to a Small Molecule Inhibitor of Viral Replication. Acs Chem.Biol., 6, 2011
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2LPW
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![BU of 2lpw by Molmil](/molmil-images/mine/2lpw) | human CEB25 minisatellite G-quadruplex | 分子名称: | DNA (26-MER) | 著者 | Amrane, S, Adrian, M, Heddi, B, Serero, A, Nicolas, A, Mergny, J.L, Phan, A.T. | 登録日 | 2012-02-20 | 公開日 | 2012-03-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Formation of Pearl-Necklace Monomorphic G-Quadruplexes in the Human CEB25 Minisatellite. J.Am.Chem.Soc., 134, 2012
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2LR1
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2LID
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2LEF
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![BU of 2lef by Molmil](/molmil-images/mine/2lef) | LEF1 HMG DOMAIN (FROM MOUSE), COMPLEXED WITH DNA (15BP), NMR, 12 STRUCTURES | 分子名称: | DNA (5'-D(*CP*AP*CP*CP*CP*TP*TP*TP*GP*AP*AP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*CP*TP*TP*CP*AP*AP*AP*GP*GP*GP*TP*G)-3'), PROTEIN (LYMPHOID ENHANCER-BINDING FACTOR) | 著者 | Li, X, Love, J.J, Case, D.A, Wright, P.E. | 登録日 | 1998-10-13 | 公開日 | 1998-10-21 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature, 376, 1995
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2L5A
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![BU of 2l5a by Molmil](/molmil-images/mine/2l5a) | Structural basis for recognition of centromere specific histone H3 variant by nonhistone Scm3 | 分子名称: | Histone H3-like centromeric protein CSE4, Protein SCM3, Histone H4 | 著者 | Zhou, Z, Feng, H, Zhou, B, Ghirlando, R, Hu, K, Zwolak, A, Jenkins, L, Xiao, H, Tjandra, N, Wu, C, Bai, Y. | 登録日 | 2010-10-28 | 公開日 | 2011-03-16 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3. Nature, 472, 2011
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2LIC
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119D
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![BU of 119d by Molmil](/molmil-images/mine/119d) | |
144D
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![BU of 144d by Molmil](/molmil-images/mine/144d) | MINOR GROOVE BINDING OF SN6999 TO AN ALKYLATED DNA: MOLECULAR STRUCTURE OF D(CGC[E6G]AATTCGCG)-SN6999 COMPLEX | 分子名称: | 1-METHYL-4-[4-[4-(4-(1-METHYLQUINOLINIUM)AMINO)BENZAMIDO]ANILINO]PYRIDINIUM, DNA (5'-D(*CP*GP*CP*(G36)P*AP*AP*TP*TP*CP*GP*CP*G)-3') | 著者 | Gao, Y.-G, Sriram, M, Denny, W.A, Wang, A.H.-J. | 登録日 | 1993-10-26 | 公開日 | 1995-05-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Minor groove binding of SN6999 to an alkylated DNA: molecular structure of d(CGC[e6G]AATTCGCG)-SN6999 complex. Biochemistry, 32, 1993
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1A6H
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1A8K
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![BU of 1a8k by Molmil](/molmil-images/mine/1a8k) | CRYSTALLOGRAPHIC ANALYSIS OF HUMAN IMMUNODEFICIENCY VIRUS 1 PROTEASE WITH AN ANALOG OF THE CONSERVED CA-P2 SUBSTRATE: INTERACTIONS WITH FREQUENTLY OCCURRING GLUTAMIC ACID RESIDUE AT P2' POSITION OF SUBSTRATES | 分子名称: | HIV PROTEASE, N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide | 著者 | Weber, I.T, Wu, J, Adomat, J, Harrison, R.W, Kimmel, A.R, Wondrak, E.M, Louis, J.M. | 登録日 | 1998-03-27 | 公開日 | 1999-01-13 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallographic analysis of human immunodeficiency virus 1 protease with an analog of the conserved CA-p2 substrate -- interactions with frequently occurring glutamic acid residue at P2' position of substrates. Eur.J.Biochem., 249, 1997
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1B5T
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![BU of 1b5t by Molmil](/molmil-images/mine/1b5t) | ESCHERICHIA COLI METHYLENETETRAHYDROFOLATE REDUCTASE | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MERCURY (II) ION, PROTEIN (METHYLENETETRAHYDROFOLATE REDUCTASE) | 著者 | Guenther, B.D, Sheppard, C.A, Tran, P, Rozen, R, Matthews, R.G, Ludwig, M.L. | 登録日 | 1999-01-07 | 公開日 | 1999-01-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia. Nat.Struct.Biol., 6, 1999
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1BIO
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![BU of 1bio by Molmil](/molmil-images/mine/1bio) | HUMAN COMPLEMENT FACTOR D IN COMPLEX WITH ISATOIC ANHYDRIDE INHIBITOR | 分子名称: | COMPLEMENT FACTOR D, GLYCEROL, ISATOIC ANHYDRIDE | 著者 | Jing, H, Babu, Y.S, Moore, D, Kilpatrick, J.M, Liu, X.-Y, Volanakis, J.E, Narayana, S.V.L. | 登録日 | 1998-06-18 | 公開日 | 1999-06-22 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity. J.Mol.Biol., 282, 1998
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1BIT
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1BIL
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![BU of 1bil by Molmil](/molmil-images/mine/1bil) | CRYSTALLOGRAPHIC STUDIES ON THE BINDING MODES OF P2-P3 BUTANEDIAMIDE RENIN INHIBITORS | 分子名称: | (2S)-2-[(2-amino-1,3-thiazol-4-yl)methyl]-N~1~-[(1S,2R,3R)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-N~4~-[2-(d imethylamino)-2-oxoethyl]-N~4~-[(1S)-1-phenylethyl]butanediamide, Renin | 著者 | Tong, L. | 登録日 | 1995-09-27 | 公開日 | 1996-01-29 | 最終更新日 | 2022-03-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystallographic studies on the binding modes of P2-P3 butanediamide renin inhibitors. J.Biol.Chem., 270, 1995
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1BG0
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![BU of 1bg0 by Molmil](/molmil-images/mine/1bg0) | TRANSITION STATE STRUCTURE OF ARGININE KINASE | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ARGININE KINASE, D-ARGININE, ... | 著者 | Zhou, G, Somasundaram, T, Blanc, E, Parthasarathy, G, Ellington, W.R, Chapman, M.S. | 登録日 | 1998-06-03 | 公開日 | 1998-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Transition state structure of arginine kinase: implications for catalysis of bimolecular reactions. Proc.Natl.Acad.Sci.USA, 95, 1998
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1BHB
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![BU of 1bhb by Molmil](/molmil-images/mine/1bhb) | Three-dimensional structure of (1-71) bacterioopsin solubilized in methanol-chloroform and SDS micelles determined by 15N-1H heteronuclear NMR spectroscopy | 分子名称: | BACTERIORHODOPSIN | 著者 | Orekhov, V.Y, Pervushin, K.V, Popov, A.I, Musina, L.Y, Arseniev, A.S. | 登録日 | 1993-10-11 | 公開日 | 1994-01-31 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure of (1-71)bacterioopsin solubilized in methanol/chloroform and SDS micelles determined by 15N-1H heteronuclear NMR spectroscopy. Eur.J.Biochem., 219, 1994
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