2L94

Structure of the HIV-1 frameshift site RNA bound to a small molecule inhibitor of viral replication

Summary for 2L94

• Entry DOI: 10.2210/pdb2l94/pdb
• Related: 1Z2J
• NMR Information: BMRB: 17436
• Descriptor: RNA_(45-MER), N'-{(Z)-amino[4-(amino{[3-(dimethylammonio)propyl]iminio}methyl)phenyl]methylidene}-N,N-dimethylpropane-1,3-diaminium (2 entities in total)
• Functional Keywords: rna, inhibitor, rna-inhibitor complex, rna/inhibitor
• Total number of polymer chains: 1
• Total formula weight: 14856.23

Authors

Marcheschi, R.J.,Tonelli, M.,Kumar, A.,Butcher, S.E. (deposition date: 2011-01-29, release date: 2011-06-15, Last modification date: 2023-06-14)

• Primary citation: Marcheschi, R.J.,Tonelli, M.,Kumar, A.,Butcher, S.E.; Structure of the HIV-1 Frameshift Site RNA Bound to a Small Molecule Inhibitor of Viral Replication.; Acs Chem.Biol., 6:857-864, 2011; PubMed: 21648432; DOI: 10.1021/cb200082d

Experimental method

SOLUTION NMR