PDB: 621 件ウェブページステータス検索Chemie searchBIRD

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1O9F	Structural view of a fungal toxin acting on a 14-3-3 regulatory complex 分子名称: 14-3-3-LIKE PROTEIN C, FUSICOCCIN, PLASMA MEMBRANE H+ ATPASE 著者 Wurtele, M, Jelich-Ottmann, C, Wittinghofer, A, Oecking, C. 登録日 2002-12-12 公開日 2003-03-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural View of a Fungal Toxin Acting on a 14-3-3 Regulatory Complex Embo J., 22, 2003
2O98	Structure of the 14-3-3 / H+-ATPase plant complex 分子名称: 14-3-3-like protein C, FUSICOCCIN, Plasma membrane H+ ATPase, ... 著者 Ottmann, C, Weyand, M, Wittinghofer, A, Oecking, C. 登録日 2006-12-13 公開日 2007-04-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+ -ATPase by combining X-ray crystallography and electron cryomicroscopy Mol.Cell, 25, 2007
2C74	14-3-3 Protein Eta (Human) Complexed to Peptide 分子名称: 14-3-3 PROTEIN ETA, CITRIC ACID, CONSENSUS PEPTIDE MODE 1 FOR 14-3-3 PROTEINS 著者 Elkins, J.M, Yang, X, Smee, C.E.A, Johansson, C, Sundstrom, M, Edwards, A, Weigelt, J, Arrowsmith, C, Doyle, D.A. 登録日 2005-11-17 公開日 2005-12-02 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for protein-protein interactions in the 14-3-3 protein family. Proc. Natl. Acad. Sci. U.S.A., 103, 2006
7A6R	Structure of 14-3-3 gamma in complex with DAPK2 peptide containing the 14-3-3 binding motif 分子名称: 14-3-3 protein gamma, DAPK2 C-terminal peptide 著者 Horvath, M, Obsilova, V, Obsil, T. 登録日 2020-08-26 公開日 2021-08-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites. Commun Biol, 4, 2021
1IB1	CRYSTAL STRUCTURE OF THE 14-3-3 ZETA:SEROTONIN N-ACETYLTRANSFERASE COMPLEX 分子名称: 14-3-3 ZETA ISOFORM, COA-S-ACETYL TRYPTAMINE, SEROTONIN N-ACETYLTRANSFERASE 著者 Obsil, T, Ghirlando, R, Klein, D.C, Ganguly, S, Dyda, F. 登録日 2001-03-26 公開日 2001-05-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation. Cell(Cambridge,Mass.), 105, 2001
5D3F	Crystal structure of human 14-3-3 zeta in complex with CFTR R-domain peptide pS753-pS768 and stabilizer fusicoccin-A 分子名称: 14-3-3 protein zeta/delta, Cystic fibrosis transmembrane conductance regulator, FUSICOCCIN 著者 Stevers, L.M, Leysen, S.F.R, Ottmann, C. 登録日 2015-08-06 公開日 2016-03-16 最終更新日 2019-03-13 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR. Proc.Natl.Acad.Sci.USA, 113, 2016
7EXE	Crystal structure of mouse 14-3-3zeta in complex with doubly phosphorylated ADAM22 peptide 分子名称: 14-3-3 protein zeta/delta, Disintegrin and metalloproteinase domain-containing protein 22 著者 Yan, L, Okatsu, K, Fukai, S. 登録日 2021-05-27 公開日 2021-11-24 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 LGI1-ADAM22 levels regulate seizure thresholds through 14-3-3 in mice Cell Rep, 2021
6YOS	Binary complex of 14-3-3 zeta with Glucocorticoid Receptor (GR) pT524 pS617 peptide 分子名称: 14-3-3 protein zeta/delta, Glucocorticoid receptor,Glucocorticoid receptor 著者 Munier, C.C, Edman, K, Perry, M.W.D, Ottmann, C. 登録日 2020-04-15 公開日 2021-03-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators. J.Biol.Chem., 296, 2021
5D3E	Crystal structure of human 14-3-3 gamma in complex with CFTR R-domain peptide pS768-pS795 分子名称: 14-3-3 protein gamma, Cystic fibrosis transmembrane conductance regulator 著者 Stevers, L.M, Leysen, S.F.R, Ottmann, C. 登録日 2015-08-06 公開日 2016-03-16 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR. Proc.Natl.Acad.Sci.USA, 113, 2016
6SAD	Structure of 14-3-3 gamma in complex with double phosphorylated caspase-2 peptide on Ser139 and Ser164 分子名称: 14-3-3 protein gamma, Caspase-2 著者 Kalabova, D, Obsil, T, Obsilova, V. 登録日 2019-07-16 公開日 2020-01-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.753 Å) 主引用文献 14-3-3 protein binding blocks the dimerization interface of caspase-2. Febs J., 287, 2020
1A4O	14-3-3 PROTEIN ZETA ISOFORM 分子名称: 14-3-3 PROTEIN ZETA 著者 Liu, D, Bienkowska, J, Petosa, C, Collier, R.J, Fu, H, Liddington, R.C. 登録日 1998-02-01 公開日 1999-03-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the zeta isoform of the 14-3-3 protein. Nature, 376, 1995
6BQT	Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and T360 分子名称: 1,2-ETHANEDIOL, 14-3-3 protein theta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... 著者 Kast, D.J, Dominguez, R. 登録日 2017-11-28 公開日 2018-12-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Mechanism of IRSp53 inhibition by 14-3-3. Nat Commun, 10, 2019
6TWZ	14-3-3 sigma complexed with a phosphorylated 16E6 peptide 分子名称: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D(-)-TARTARIC ACID, ... 著者 Gogl, G, Cousido-Siah, A, Sluchanko, N.N, Trave, G. 登録日 2020-01-13 公開日 2020-05-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study. Structure, 28, 2020
1YZ5	The crystal structure of 14-3-3-sigma at 2.8 angstrom resolution 分子名称: 14-3-3 protein sigma 著者 Benzinger, A, Popowicz, G.M, Holak, T.A, Hermeking, H. 登録日 2005-02-28 公開日 2005-03-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The crystal structure of the non-liganded 14-3-3sigma protein: insights into determinants of isoform specific ligand binding and dimerization. Cell Res., 15, 2005
2BTP	14-3-3 Protein Theta (Human) Complexed to Peptide 分子名称: 14-3-3 PROTEIN TAU, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS 著者 Elkins, J.M, Johansson, A.C.E, Smee, C, Yang, X, Sundstrom, M, Edwards, A, Arrowsmith, C, Doyle, D.A, Structural Genomics Consortium (SGC) 登録日 2005-06-05 公開日 2005-06-28 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Basis for Protein-Protein Interactions in the 14-3-3 Protein Family. Proc.Natl.Acad.Sci.USA, 103, 2006
6FEL	Structure of 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser511 分子名称: 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2 著者 Lentini Santo, D, Obsilova, V, Obsil, T. 登録日 2018-01-02 公開日 2018-01-10 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2). Biochim. Biophys. Acta, 1862, 2018
6GKG	Structure of 14-3-3 gamma in complex with caspase-2 14-3-3 binding motif Ser164 分子名称: 14-3-3 protein gamma, Caspase-2 著者 Alblova, M, Obsil, T, Obsilova, V. 登録日 2018-05-20 公開日 2018-10-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.847 Å) 主引用文献 14-3-3 protein masks the nuclear localization sequence of caspase-2. FEBS J., 285, 2018
4ZDR	Crystal structure of 14-3-3[zeta]-LKB1 fusion protein 分子名称: 14-3-3 protein zeta/delta,GGSGGS linker,Serine/threonine-protein kinase STK11, GLYCEROL, PROPANE, ... 著者 Ding, S, Shi, Z.B. 登録日 2015-04-18 公開日 2015-09-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.899 Å) 主引用文献 Structure of the 14-3-3 zeta-LKB1 fusion protein provides insight into a novel ligand-binding mode of 14-3-3. Acta Crystallogr.,Sect.F, 71, 2015
6TLF	human 14-3-3 sigma isoform in complex with IMP 分子名称: 14-3-3 protein sigma, INOSINIC ACID, SULFATE ION 著者 Tassone, G, Pozzi, C, Mangani, S. 登録日 2019-12-02 公開日 2020-03-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction. Acs Chem.Biol., 15, 2020
8AH2	Crystal structure of human 14-3-3 zeta fused to the NPM1 peptide including phosphoserine-48 分子名称: 14-3-3 protein zeta/delta,Nucleophosmin 著者 Boyko, K.M, Kapitonova, A.A, Tugaeva, K.V, Varfolomeeva, L.A, Sluchanko, N.N. 登録日 2022-07-20 公開日 2022-09-14 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for the recognition by 14-3-3 proteins of a conditional binding site within the oligomerization domain of human nucleophosmin. Biochem.Biophys.Res.Commun., 627, 2022
6BD2	Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and S366 分子名称: 1,2-ETHANEDIOL, 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, ... 著者 Kast, D.J, Dominguez, R. 登録日 2017-10-20 公開日 2018-10-24 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Mechanism of IRSp53 inhibition by 14-3-3. Nat Commun, 10, 2019
6BYJ	Structure of human 14-3-3 gamma bound to O-GlcNAc peptide 分子名称: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, TSTTATPPVSQASSTTTSTW O-GlcNac peptide 著者 Schumacher, M.A. 登録日 2017-12-20 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins. Proc.Natl.Acad.Sci.USA, 115, 2018
4O46	14-3-3-gamma in complex with influenza NS1 C-terminal tail phosphorylated at S228 分子名称: 14-3-3 protein gamma, Nonstructural protein 1, UNKNOWN ATOM OR ION, ... 著者 Qin, S, Liu, Y, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2013-12-18 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
6QK8	Crystal structure of yeast 14-3-3 protein (Bmh1) from Saccharomyces cerevisiae with the Nha1p (yeast Na+/H+ antiporter) 14-3-3 binding motif Ser481 分子名称: Na(+)/H(+) antiporter, Protein BMH1 著者 Smidova, A, Obsil, T, Obsilova, V. 登録日 2019-01-28 公開日 2019-10-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.917 Å) 主引用文献 The activity of Saccharomyces cerevisiae Na+, K+/H+antiporter Nha1 is negatively regulated by 14-3-3 protein binding at serine 481. Biochim Biophys Acta Mol Cell Res, 1866, 2019
5WXN	Structure of the LKB1 and 14-3-3 complex 分子名称: 14-3-3 protein zeta/delta, Serine/threonine-protein kinase STK11 著者 Ding, S, Shi, Z.B. 登録日 2017-01-08 公開日 2017-04-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Structure of the complex of phosphorylated liver kinase B1 and 14-3-3 zeta Acta Crystallogr F Struct Biol Commun, 73, 2017

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