6BQT

Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and T360

Summary for 6BQT

• Entry DOI: 10.2210/pdb6bqt/pdb
• Related: 6BCR 6BCY
• Descriptor: 14-3-3 protein theta, Insulin receptor substrate protein of 53 kDa, peptide (IRSp53), 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... (10 entities in total)
• Functional Keywords: phosphate binding protein, protein complex, cytoskeleton regulation, cell motility, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 240310.84

Authors

Kast, D.J.,Dominguez, R. (deposition date: 2017-11-28, release date: 2018-12-05, Last modification date: 2023-10-04)

• Primary citation: Kast, D.J.,Dominguez, R.; Mechanism of IRSp53 inhibition by 14-3-3.; Nat Commun, 10:483-483, 2019; PubMed: 30696821; DOI: 10.1038/s41467-019-08317-8

Experimental method

X-RAY DIFFRACTION (2.8 Å)