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6BQT

Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and T360

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, D, E, G...
(A, B, D, E, G...)
14-3-3 protein thetapolymer24527795.28UniProt (P27348)
Pfam (PF00244)
Homo sapiens (Human)14-3-3 protein T-cell,14-3-3 protein tau,Protein HS1
2C, F, I, L
(C, F, I, L)
Insulin receptor substrate protein of 53 kDa, peptide (IRSp53)polymer323694.84UniProt (Q9UQB8)Homo sapiensProtein BAP2,Fas ligand-associated factor 3,FLAF3,Insulin receptor substrate p53/p58,IRSp53/58,Insulin receptor substrate protein of 53 kDa,Insulin receptor substrate p53
3M
(A)
2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOLnon-polymer354.41Chemie (PE4)
4BA, CA, N, O, Q...
(J, A, B, G, H)
PENTAETHYLENE GLYCOLnon-polymer238.37Chemie (1PE)
5P, U
(B, D)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
6R, T, V
(B, D, E)
TETRAETHYLENE GLYCOLnon-polymer194.23Chemie (PG4)
7AA, S
(I, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
8W
(E)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
9X
(E)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
10DA, EA, FA, GA, HA...
(A, B, C, D, E...)
waterwater18.093Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight237141.2
Non-Polymers*Number of molecules17
Total formula weight3169.7
All*Total formula weight240310.8
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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