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1CEN
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BU of 1cen by Molmil
CELLULASE (CELC) MUTANT WITH GLU 140 REPLACED BY GLN COMPLEXED WITH CELLOHEXAOSE
Descriptor: CELLULASE CELC, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
Authors:Dominguez, R, Alzari, P.M.
Deposit date:1995-12-04
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of a family 5 endoglucanase mutant in complexed and uncomplexed forms reveals an induced fit activation mechanism.
J.Mol.Biol., 257, 1996
1CEO
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BU of 1ceo by Molmil
CELLULASE (CELC) MUTANT WITH GLU 140 REPLACED BY GLN
Descriptor: CELLULASE CELC
Authors:Dominguez, R, Alzari, P.M.
Deposit date:1995-12-04
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of a family 5 endoglucanase mutant in complexed and uncomplexed forms reveals an induced fit activation mechanism.
J.Mol.Biol., 257, 1996
1BR2
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BU of 1br2 by Molmil
SMOOTH MUSCLE MYOSIN MOTOR DOMAIN COMPLEXED WITH MGADP.ALF4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN, ...
Authors:Dominguez, R, Trybus, K.M, Cohen, C.
Deposit date:1998-08-26
Release date:1998-09-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
Cell(Cambridge,Mass.), 94, 1998
1BR1
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BU of 1br1 by Molmil
SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.ALF4 BOUND AT THE ACTIVE SITE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN, ...
Authors:Dominguez, R, Trybus, K.M, Cohen, C.
Deposit date:1998-08-26
Release date:1998-09-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
Cell(Cambridge,Mass.), 94, 1998
1BR4
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BU of 1br4 by Molmil
SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.BEF3 BOUND AT THE ACTIVE SITE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Dominguez, R, Trybus, K.M, Cohen, C.
Deposit date:1998-08-27
Release date:1998-09-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
Cell(Cambridge,Mass.), 94, 1998
1CEC
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BU of 1cec by Molmil
A COMMON PROTEIN FOLD AND SIMILAR ACTIVE SITE IN TWO DISTINCT FAMILIES OF BETA-GLYCANASES
Descriptor: ENDOGLUCANASE CELC
Authors:Alzari, P.M, Dominguez, R.
Deposit date:1995-06-07
Release date:1996-01-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A common protein fold and similar active site in two distinct families of beta-glycanases.
Nat.Struct.Biol., 2, 1995
6PSD
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BU of 6psd by Molmil
Complex of CRACR2a with a Dynein Light Intermediate Chain Peptide
Descriptor: CALCIUM ION, EF-hand calcium-binding domain-containing protein 4B, cDNA FLJ10219 fis, ...
Authors:Dominguez, R, Lee, I.G.
Deposit date:2019-07-12
Release date:2020-07-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner.
Nat Commun, 11, 2020
6PSE
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BU of 6pse by Molmil
Complex of BICD2 with a Dynein Light Intermediate Chain Peptide
Descriptor: Cytoplasmic dynein 1 light intermediate chain 1, Protein bicaudal D homolog 2
Authors:Dominguez, R, Lee, I.G.
Deposit date:2019-07-12
Release date:2020-07-15
Last modified:2021-07-28
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner.
Nat Commun, 11, 2020
1XYZ
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BU of 1xyz by Molmil
A COMMON PROTEIN FOLD AND SIMILAR ACTIVE SITE IN TWO DISTINCT FAMILIES OF BETA-GLYCANASES
Descriptor: 1,4-BETA-D-XYLAN-XYLANOHYDROLASE
Authors:Alzari, P.M, Spinelli, S, Dominguez, R.
Deposit date:1995-06-07
Release date:1996-01-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A common protein fold and similar active site in two distinct families of beta-glycanases.
Nat.Struct.Biol., 2, 1995
8TAH
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BU of 8tah by Molmil
Cryo-EM structure of Cortactin-bound to Arp2/3 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ...
Authors:Fregoso, F.E, van Eeuwen, T, Dominguez, R.
Deposit date:2023-06-27
Release date:2023-09-27
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins.
Nat Commun, 14, 2023
5V7X
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BU of 5v7x by Molmil
Crystal Structure of Myosin 1b residues 1-728 with bound sulfate and Calmodulin
Descriptor: Calmodulin-1, SULFATE ION, Unconventional myosin-Ib
Authors:Zwolak, A, Shuman, H, Dominguez, R, Ostap, E.M.
Deposit date:2017-03-20
Release date:2018-02-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.141 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7JPN
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BU of 7jpn by Molmil
Cryo-EM structure of Arpin-bound Arp2/3 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ...
Authors:van Eeuwen, T, Fregoso, F.E, Dominguez, R, Zimmet, A, Boczkowska, M, Rebowski, G.
Deposit date:2020-08-09
Release date:2022-02-09
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Molecular mechanism of Arp2/3 complex inhibition by Arpin.
Nat Commun, 13, 2022
1IC2
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BU of 1ic2 by Molmil
DECIPHERING THE DESIGN OF THE TROPOMYOSIN MOLECULE
Descriptor: TROPOMYOSIN ALPHA CHAIN, SKELETAL MUSCLE
Authors:Brown, J.H, Kim, K.-H, Jun, G, Greenfield, N.J, Dominguez, R, Volkmann, N, Hitchcock-DeGregori, S.E, Cohen, C.
Deposit date:2001-03-29
Release date:2001-07-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Deciphering the design of the tropomyosin molecule
Proc.Natl.Acad.Sci.USA, 98, 2001
5WFN
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BU of 5wfn by Molmil
Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT)
Descriptor: Actin-5C, Leiomodin-2, MAGNESIUM ION, ...
Authors:Yurtsever, Z, Eck, M.J, Dominguez, R.
Deposit date:2017-07-12
Release date:2017-08-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of leiomodin 2 in complex with actin: a structural and functional reexamination
Biophys.J., 113, 2017
5TGC
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BU of 5tgc by Molmil
Structure of the hetero-trimer of Rtt102-Arp7/9 bound to ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-like protein ARP9, Actin-related protein 7, ...
Authors:Turegun, B, Dominguez, R.
Deposit date:2016-09-27
Release date:2017-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.245 Å)
Cite:Actin-related proteins regulate the RSC chromatin remodeler by weakening intramolecular interactions of the Sth1 ATPase.
Commun Biol, 1, 2018
6NBW
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BU of 6nbw by Molmil
Ternary Complex of Beta/Gamma-Actin with Profilin and AnCoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-10
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NAS
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BU of 6nas by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and AcCoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-06
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NBE
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BU of 6nbe by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and CoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-07
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6UHC
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BU of 6uhc by Molmil
CryoEM structure of human Arp2/3 complex with bound NPFs
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ...
Authors:Zimmet, A, van Eeuwen, T, Dominguez, R.
Deposit date:2019-09-27
Release date:2020-07-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism.
Sci Adv, 6, 2020
3T62
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BU of 3t62 by Molmil
Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Caribbean Sea anemone Stichodactyla helianthus in complex with bovine chymotrypsin
Descriptor: Chymotrypsinogen A, Kunitz-type proteinase inhibitor SHPI-1, SULFATE ION
Authors:Garcia-Fernandez, R, Dominguez, R, Oberthuer, D, Pons, T, Gonzalez-Gonzalez, Y, Chavez, M.A, Betzel, C, Redecke, L.
Deposit date:2011-07-28
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into chymotrypsin inhibition by the Kunitz-type inhibitor-1 from the marine invertebrate Stichodactyla helianthus
To be Published
3U59
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BU of 3u59 by Molmil
N-terminal 98-aa fragment of smooth muscle tropomyosin beta
Descriptor: Tropomyosin beta chain
Authors:Jampani, N, Dominguez, R.
Deposit date:2011-10-11
Release date:2011-11-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of smooth muscle tropomyosin alpha and beta isoforms.
J.Biol.Chem., 287, 2012
3U1A
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BU of 3u1a by Molmil
N-terminal 81-aa fragment of smooth muscle tropomyosin alpha
Descriptor: smooth muscle tropomyosin alpha
Authors:Jampani, N, Dominguez, R.
Deposit date:2011-09-29
Release date:2011-11-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of smooth muscle tropomyosin alpha and beta isoforms.
J.Biol.Chem., 287, 2012
3U1C
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BU of 3u1c by Molmil
Anti-parallel dimer of N-terminal 98-aa fragment of smooth muscle tropomyosin alpha
Descriptor: Tropomyosin alpha-1 chain
Authors:Jampani, N, Dominguez, R.
Deposit date:2011-09-29
Release date:2011-11-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of smooth muscle tropomyosin alpha and beta isoforms.
J.Biol.Chem., 287, 2012
7T5Q
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BU of 7t5q by Molmil
Cryo-EM Structure of a Transition State of Arp2/3 Complex Activation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, van Eeuwen, T, Boczkowska, M, Dominguez, R.
Deposit date:2021-12-13
Release date:2023-06-14
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of an Arp2/3 complex mini-branch capped by capping protein (CapZ)
To Be Published
8F8T
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BU of 8f8t by Molmil
Cryo-EM structure of the Tropomodulin-capped pointed end of F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Carman, P.J, Barrie, K.R, Dominguez, R.
Deposit date:2022-11-22
Release date:2023-06-07
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structures of the free and capped ends of the actin filament.
Science, 380, 2023

 

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