6FEL

Structure of 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser511

Summary for 6FEL

• Entry DOI: 10.2210/pdb6fel/pdb
• Descriptor: 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2 (3 entities in total)
• Functional Keywords: 14-3-3 protein, calcium/calmodulin-dependent protein kinase kinase 2, camkk2, phosphorylation, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 112325.90

Authors

Lentini Santo, D.,Obsilova, V.,Obsil, T. (deposition date: 2018-01-02, release date: 2018-01-10, Last modification date: 2024-01-17)

• Primary citation: Psenakova, K.,Petrvalska, O.,Kylarova, S.,Lentini Santo, D.,Kalabova, D.,Herman, P.,Obsilova, V.,Obsil, T.; 14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).; Biochim. Biophys. Acta, 1862:1612-1625, 2018; PubMed: 29649512; DOI: 10.1016/j.bbagen.2018.04.006

Experimental method

X-RAY DIFFRACTION (2.84 Å)