7A6R

Structure of 14-3-3 gamma in complex with DAPK2 peptide containing the 14-3-3 binding motif

Summary for 7A6R

• Entry DOI: 10.2210/pdb7a6r/pdb
• Descriptor: 14-3-3 protein gamma, DAPK2 C-terminal peptide (3 entities in total)
• Functional Keywords: 14-3-3 protein, dapk2, kinase, complex, phosphorylation, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 112526.16

Authors

Horvath, M.,Obsilova, V.,Obsil, T. (deposition date: 2020-08-26, release date: 2021-08-25, Last modification date: 2024-01-31)

• Primary citation: Horvath, M.,Petrvalska, O.,Herman, P.,Obsilova, V.,Obsil, T.; 14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites.; Commun Biol, 4:986-986, 2021; PubMed: 34413451; DOI: 10.1038/s42003-021-02518-y

Experimental method

X-RAY DIFFRACTION (2.7 Å)